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The map label for this gene is frdD [H]

Identifier: 37681284

GI number: 37681284

Start: 3181568

End: 3181945

Strand: Direct

Name: frdD [H]

Synonym: VV3100

Alternate gene names: 37681284

Gene position: 3181568-3181945 (Clockwise)

Preceding gene: 37681283

Following gene: 37681287

Centisome position: 94.84

GC content: 49.47

Gene sequence:

>378_bases
ATGAAACCGAATTACAACGTAGATAGAGCGCCAAAACGTTCTGATGAGCCAGTTTGGTGGAGCTTGTTTGGTGCAGGTGG
TACTTGGTTTGCCATGATCACACCAGTTACTGTTTTGGTGCTGGGTATTCTCGTGCCAATGGGCGTGATCAATGCAGAAG
CACTGAGTTACGACCGAGTGGTGAGCTTTGCCACCAGCATCATCGGCGCATTGTTTATCATCGCGACACTGGCCTTACCA
ATGTGGCATGCGATGCACCGTGTTCACCACGGCATGCATGATCTCAAATTCCACACTGGCGTGGTCGGCAAAATTGCCTG
TTACGCGATTGCTGGATTGATTTCAGCATTGGCGGTGGTGTTCATTTTCATGCTGTAA

Upstream 100 bases:

>100_bases
GGGCAAACCTGTTGATAAGAAAATCATCGTGCTCGCTCAGTGGGCCGCGGTGGCATTTATCTCACTGATTGTACTTATCG
TGGTGTAAGGAGCTTTAACG

Downstream 100 bases:

>100_bases
GCATGGCGCACTGAAAAAGAAAAAGCTGGCTTGTCGCCAGCTTTTTTATTGTCATTGCTTCAAGTGGTTTATTTATTGAC
CACTTTCTTGGTTTGGTCCA

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAIAGLISALAVVFIFML

Sequences:

>Translated_125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAIAGLISALAVVFIFML
>Mature_125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAIAGLISALAVVFIFML

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=114, Percent_Identity=48.2456140350877, Blast_Score=122, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.99.1

Molecular weight: Translated: 13665; Mature: 13665

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFATSIIGALFIIATLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAIAGLISALAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIFML
HHHHC
>Mature Secondary Structure
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFATSIIGALFIIATLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAIAGLISALAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIFML
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA