| Definition | Vibrio vulnificus YJ016 chromosome I, complete sequence. |
|---|---|
| Accession | NC_005139 |
| Length | 3,354,505 |
Click here to switch to the map view.
The map label for this gene is uvrA
Identifier: 37681140
GI number: 37681140
Start: 3021692
End: 3024550
Strand: Direct
Name: uvrA
Synonym: VV2956
Alternate gene names: 37681140
Gene position: 3021692-3024550 (Clockwise)
Preceding gene: 37681139
Following gene: 37681141
Centisome position: 90.08
GC content: 48.72
Gene sequence:
>2859_bases TTGCTCAACTTGTTGGTATTACACAGAGCATCAAAGATGGACAAGATAGAAGTTCGCGGAGCACGTACCCATAATCTCAA AAACATAAATCTCACCATTCCCCGAGATAAACTGATCGTTATTACGGGCTTATCCGGCTCAGGTAAGTCTTCTTTGGCAT TTGACACTTTGTACGCAGAGGGTCAGCGACGTTATGTGGAATCCCTCTCTGCTTATGCTCGTCAATTTCTTTCATTGATG GAAAAGCCCGACGTTGACCACATTGAAGGCCTCTCGCCAGCAATTTCTATCGAGCAAAAATCCACCTCACACAACCCGCG TTCAACCGTAGGGACCATCACGGAAGTGTATGACTACCTTCGCCTACTGTATGCCCGCGTTGGTGAGCCTCGCTGTCCTG ACCACAAAGTCCCTTTAGCGGCTCAAACCATTAGCCAAATGGTCGACAAAGTGCTTGAGCTGCCTGAAGGTGCCAAAATG ATGTTGCTCGCCCCCATCGTGAAAGAGCGCAAAGGCGAGCACGTTAAAACATTAGAGAATCTTGCTGCTCAAGGTTTTAT TCGTGCGCGTATTGACGGAGAGACCTGTGACCTCACCGATCCACCAACGCTAGAGTTACACAAAAAGCACACCATTGAAG TGGTGGTTGACCGCTTTAAAGTGCGTGGCGATTTACAACAAAGGCTCGCAGAATCCTTTGAAACGGCACTGGAACTCTCA GGTGGCATCGCTGTGATTGCCCCTATGGAGGGTGACGGTGAAGAGATCGTTTTTTCCGCCAATTTTGCGTGTCCCCACTG TGGTTATAGTATGCAAGAGCTTGAGCCACGTTTGTTCTCGTTCAATAACCCAGCAGGGGCTTGTGGCACCTGTGATGGCC TCGGGGTACAGCAATATTTTGACCCAGAACGTGTGATTCAAGATGCCAATTTAAGTCTTGCACAAGGGGCGATTCGTGGT TGGGATCAGAAGAACTATTACTATTTCCAAATGCTCACCTCGCTGGCTGAGCATTACGATTTCGATTTACATGCCCCTTT TAATTCGCTTTCAAAACGCATCCAAGAGGTCATATTAAAAGGCTCAGGGCGCACTGAAATCGAATTTAAGTACATCAACG ATCGAGGCGACATTCGTCTTAAACGCCATCCATTTGAAGGTATTCTCAATACACTCGAGCGCCGTTATCGCGACACCGAA TCTAACTCGGTACGAGAAGAGTTGGTGAAATATATCTCCACCAAACCTTGCACCAGTTGTGGCGGAACGCGTCTGCGCCT AGAAGCACGCAACGTGTTTATTAATGACACGACATTGCCACAAATCGTCGAGTTGAGTATCGCGGATGCATTGACCTTTT TCGCCACCTTAAAACTCGAAGGGCAGCGAGCTCAAATTGCGGAGAAGGTCATGAAAGAGATCAACGATCGACTGCAGTTT TTAGTCAACGTTGGCCTCAATTATTTGAACCTGTCTCGCAGCGCTGAAACCTTGTCTGGTGGCGAAGCACAGCGTATTCG TCTGGCTAGCCAGATCGGTGCCGGTTTGGTTGGCGTGATGTACGTGCTCGATGAACCGTCAATCGGCCTTCACCAGCGTG ACAACGAGCGCTTACTCAAAACACTGACGCACTTACGCGATCTCGGCAATACCGTATTAGTCGTAGAGCATGATGAAGAT GCGATTCGTTGTGCCGACCATGTGATTGATATTGGCCCTGGTGCAGGCGTACATGGTGGCCAAGTGGTTGCCGAAGGAAC AATGGCCGAGATTCTCGCCAATCCAGATTCCTTGACCGGACAATACTTGAGCGGTGCCAAGCAGATTATTGTGCCGACTC AACGCACACCAAGAGATAAGAACAAAACCGTTGAGCTCATTGGAGCCAGTGGCAACAACCTTAAAGAGGTCAATCTTTCG GTGCCTGTCGGGCTATTCAGTTGTATCACCGGGGTTTCTGGTTCGGGTAAATCAACACTGATTAACGACACCTTCTTCAA AATTGCTCATACCCAACTCAATGGGGCGACCACAGCTCAACCAGCGCCTTATAAGTCTATTAAAGGCTTAGAGCATTTTG ATAAGGTCATCGATATCGACCAGAGCCCCATCGGTCGCACACCGCGTTCAAATCCAGCAACCTATACGGGGATTTTCACT CCGATTCGAGAGTTGTTCTCCGGCACTCAAGAGTCTCGTTCACGTGGCTACAAGCCAGGGCGTTTCAGCTTTAACGTTCG TGGTGGCCGCTGTGAAGCTTGCCAAGGTGATGGTGTTATCAAGGTTGAAATGCACTTTTTACCTGATGTTTACGTCCCTT GTGATGTGTGTAAAGGCAAGCGCTACAACCGTGAAACGTTAGAAGTACACTACAAAGGGAAGAGCATCGATGAAGTGCTA GAGATGACCGTTGAAGACGCTCATGAGTTTTTCGCTCCTGTCCCTGTCATCGCGCGTAAACTGCAAACCTTAATGGATGT TGGTCTTTCTTATATCCGTTTAGGTCAAGCGGCCACCACCCTCTCTGGCGGTGAAGCACAACGGGTGAAACTGGCCCGTG AGTTGTCCAAACGCGATACGGGCAAAACCCTTTATATTTTGGATGAACCAACAACGGGCCTACACTTCCACGATATCCAG CAACTTTTGACCGTATTGCATCGCTTACGTGATCATGGCAACACCGTTGTCGTGATTGAGCATAATTTAGATGTGATCAA AACGGCCGATTGGATCATCGACTTAGGTCCAGAAGGCGGCCAAGGTGGAGGGGAAATCATTGCCCAAGGAACACCTGAAG ATGTGGCGCAGATCGAAGGTTCGCATACCGCACGCTTCCTTAAGCCTATGTTGAAATAG
Upstream 100 bases:
>100_bases TTCCTCTAAACCGAGACGTAAGGCGCTTTTATAAAGCGCCTTATTTTTAACTGTTTTTTTATCCAGTATTTTATTGCACA TTTCTCACACTATGTAATAC
Downstream 100 bases:
>100_bases AAAAAACAGGTAAAGTGATGAAACCAGCGTAAAGCTGGTTTCTTTTTTCAGATTAAGAATCACGTTATGGCAACGATACA CGTAAGCGGTACGCAATTAG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 952; Mature: 952
Protein sequence:
>952_residues MLNLLVLHRASKMDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLM EKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKM MLLAPIVKERKGEHVKTLENLAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELS GGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVIQDANLSLAQGAIRG WDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILKGSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTE SNSVREELVKYISTKPCTSCGGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQF LVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVLVVEHDED AIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTGQYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLS VPVGLFSCITGVSGSGKSTLINDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFT PIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVHYKGKSIDEVL EMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQ QLLTVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK
Sequences:
>Translated_952_residues MLNLLVLHRASKMDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLM EKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKM MLLAPIVKERKGEHVKTLENLAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELS GGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVIQDANLSLAQGAIRG WDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILKGSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTE SNSVREELVKYISTKPCTSCGGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQF LVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVLVVEHDED AIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTGQYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLS VPVGLFSCITGVSGSGKSTLINDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFT PIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVHYKGKSIDEVL EMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQ QLLTVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK >Mature_952_residues MLNLLVLHRASKMDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLM EKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKM MLLAPIVKERKGEHVKTLENLAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELS GGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVIQDANLSLAQGAIRG WDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILKGSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTE SNSVREELVKYISTKPCTSCGGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQF LVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVLVVEHDED AIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTGQYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLS VPVGLFSCITGVSGSGKSTLINDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFT PIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVHYKGKSIDEVL EMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQ QLLTVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=80.2127659574468, Blast_Score=1570, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 105373; Mature: 105373
Theoretical pI: Translated: 6.69; Mature: 6.69
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNLLVLHRASKMDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAE CCEEEEEECCCCCCEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHH GQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYL HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH RLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKMMLLAPIVKERKGEHVKTLEN HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCHHHHHHH LAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELS HHHCCEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC GGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYF CCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCCHHHC DPERVIQDANLSLAQGAIRGWDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILK CHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC GSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTESNSVREELVKYISTKPCTSC CCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC GGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQF CCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH LVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLK HHHHCCCCEECCCCCHHCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHH TLTHLRDLGNTVLVVEHDEDAIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTG HHHHHHHCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCEEEECCHHHHHHCCCCCCCH QYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLSVPVGLFSCITGVSGSGKSTL HHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHCCCCCCCCEE INDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFT ECCHHHEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHH PIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGK HHHHHHCCCHHHHHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCC RYNRETLEVHYKGKSIDEVLEMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATT CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHC LSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHRLRDHGNTVVVIE CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE HNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK CCCCEEEECCEEEEECCCCCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHCC >Mature Secondary Structure MLNLLVLHRASKMDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAE CCEEEEEECCCCCCEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHH GQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYL HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH RLLYARVGEPRCPDHKVPLAAQTISQMVDKVLELPEGAKMMLLAPIVKERKGEHVKTLEN HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCHHHHHHH LAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRFKVRGDLQQRLAESFETALELS HHHCCEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC GGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYF CCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHCCCHHEECCCCCCCCCCCCCCCCHHHC DPERVIQDANLSLAQGAIRGWDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILK CHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC GSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTESNSVREELVKYISTKPCTSC CCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC GGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQF CCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH LVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLK HHHHCCCCEECCCCCHHCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHH TLTHLRDLGNTVLVVEHDEDAIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTG HHHHHHHCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCEEEECCHHHHHHCCCCCCCH QYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLSVPVGLFSCITGVSGSGKSTL HHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHCCCCCCCCEE INDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFT ECCHHHEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHH PIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGK HHHHHHCCCHHHHHCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCC RYNRETLEVHYKGKSIDEVLEMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATT CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCHHHC LSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHRLRDHGNTVVVIE CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE HNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK CCCCEEEECCEEEEECCCCCCCCCCEEECCCCHHHHHCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]