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The map label for this gene is hlyB [H]

Identifier: 37679891

GI number: 37679891

Start: 1759101

End: 1760858

Strand: Direct

Name: hlyB [H]

Synonym: VV1707

Alternate gene names: 37679891

Gene position: 1759101-1760858 (Clockwise)

Preceding gene: 37679890

Following gene: 37679893

Centisome position: 52.44

GC content: 48.52

Gene sequence:

>1758_bases
ATGTCCGGATCACCTGTTCAAAAACGTTTTTTCTTTTCATTCTCTATCCGAGCCAAACTGCTGCTCATCAATGTGACTTT
GCTGTTAGGCGTTGCCGCCTACGCGATTTATGAGAACAACAGCGCAAAGCATTTGTCCTCTTTGGAGCACGCCTCAACAG
AAAACTTAAGCAGTTCCATTGATCTGTTGATGCTTCGCCGACACGAGAAAGATTATTTGGCTCGTCGCAGCGAAAAATAC
TTGACGAGTTTCGATGCTACCTATTCTCAACTGCAACAGCGCATTGACCACTTATCAGACGTTCTTGCCAGTGAGTCGAT
TGCCATTGACGATCAACGTCAGCAAATTGTAACCACTCTATCTCAGTATCAAACTCAGTTTCATCAATTGGCCGCTCAGC
TAGCAAACATTGACGCGCTGCAAAGTGAGCTATTTGCTGCACGCAGCATGCTTAAAACCAATGTACTCAGTGCTAATGAT
GGAGAGCTTACTGCGCAGTTTTTGCAGTTGCTTGACCACGATTTAACTTTTGTCACCGAACCAACGCAAGAGCACAAGGT
GGCGCTGCTCGAAGGGCTTAGCCAGTTTGCCAAGTTTGAAGCCGATTTGTCTCCCGCTTTTACCGATTATTCCAACACCT
TATCTCGATACGTCAGCGCGATCGAAACGCTTGGCTTAACTGCAAACGAAGGTCTAAGAGGCGCGCTCCGTAGCAATGTG
CACAAAACCGAACAGGCGATTACCGATTTACAAACCACCATCAAGCAGGGCGTTGAGCAAACTGCAGCGGATATTCGCAG
CCACTTACAGTGGATGGGCGTGGTGATCGTCGTGCTTTTATCGTCACTGCTCTACGTCATTGGCCGTAGTATTCTTTCGA
GAATCAAAGCCATTAACCTTTTGATGGATGACATTGCCAATGGCAGCGGAGATTTAACGGTACGAATGAATGCCAAAGGC
AGTGACGAGCTAGCGCAGTTATCCCGCTCATTTGACCTCTTTATCAGCCACCTACATGACAACATCAAACAACTGGCGTC
TGTGATGGATGTATTAGGTGAAAGCTCCTGCAGCTCAGAGCAAGCAGCGCAGAGAAGTATGCAAAATGCACAACGAGTGA
ATAGCGAAGCCGATAAAGCACTGCAACTCACCCACGCGACAGGTAAGCGAATTGATACGTTAGCCATCAGTATCGAAGAG
TCGCAAGCTCAGATCCAAGCACTTGAAGCACAAAGCCGCGAAATCAATGCCGTTGTCTCTGCCATTCAAGGCATTGCAGA
GCAAACCAACCTGCTGGCACTAAATGCGGCCATTGAAGCAGCGCGCGCCGGAGAAAGTGGCCGAGGGTTTGCCGTGGTCG
CCGATGAAGTTCGCCAGCTCTCTCGGCTAACCAATGATTCCACCTTGCAAATTGAATCCACCGTCCAAGCACTGACAAAA
GGGATCGCTCAAACGGTCAACAAAATGGCAGACAGTGTCGATCAAGCTCGGACAACGAATGTGGATACGCGCCATGTGAT
CGAAGCGATTGAAGGCATCAGCACGCAAATCACCGAGATGTTTGATATGAACACGCAGATTGCGACCGCGTCAGAAGAGC
AATCCATGGTATCAGCAGAAATTGACCGCAATATTACGCAAATCGCGCAGCTGGCGGGGGATACTTATGAGATCGTTTCT
GGCTCTGTCCGATGCAGCGAACAAGTGTCGGATGTTAGCCACAAGCTGGAAAAGATCGTCGCCCAATTTAAGTATTGA

Upstream 100 bases:

>100_bases
ATGCGCTATTAGTTGAATATTCTCTGCAATAAATTTGAAACATAAATGAAACAAAAGCGGAGATAGGTTAACTACGTCAC
TGGCTAAATGGGAGGTATCC

Downstream 100 bases:

>100_bases
ACGCCCTAACCTCCTTGCCCTCATCGACTTAGTGACGACAGATAGCAGAAAAAGCAAAAGAGCCTCAGTGAGGCTCTTTG
TTTGATCTTTTTAAGCACGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKY
LTSFDATYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLANIDALQSELFAARSMLKTNVLSAND
GELTAQFLQLLDHDLTFVTEPTQEHKVALLEGLSQFAKFEADLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
HKTEQAITDLQTTIKQGVEQTAADIRSHLQWMGVVIVVLLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKG
SDELAQLSRSFDLFISHLHDNIKQLASVMDVLGESSCSSEQAAQRSMQNAQRVNSEADKALQLTHATGKRIDTLAISIEE
SQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTK
GIAQTVNKMADSVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVS
GSVRCSEQVSDVSHKLEKIVAQFKY

Sequences:

>Translated_585_residues
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKY
LTSFDATYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLANIDALQSELFAARSMLKTNVLSAND
GELTAQFLQLLDHDLTFVTEPTQEHKVALLEGLSQFAKFEADLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
HKTEQAITDLQTTIKQGVEQTAADIRSHLQWMGVVIVVLLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKG
SDELAQLSRSFDLFISHLHDNIKQLASVMDVLGESSCSSEQAAQRSMQNAQRVNSEADKALQLTHATGKRIDTLAISIEE
SQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTK
GIAQTVNKMADSVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVS
GSVRCSEQVSDVSHKLEKIVAQFKY
>Mature_584_residues
SGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKYL
TSFDATYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLANIDALQSELFAARSMLKTNVLSANDG
ELTAQFLQLLDHDLTFVTEPTQEHKVALLEGLSQFAKFEADLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNVH
KTEQAITDLQTTIKQGVEQTAADIRSHLQWMGVVIVVLLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKGS
DELAQLSRSFDLFISHLHDNIKQLASVMDVLGESSCSSEQAAQRSMQNAQRVNSEADKALQLTHATGKRIDTLAISIEES
QAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKG
IAQTVNKMADSVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSG
SVRCSEQVSDVSHKLEKIVAQFKY

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=29.7546012269939, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=243, Percent_Identity=32.0987654320988, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788194, Length=238, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787690, Length=335, Percent_Identity=28.0597014925373, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789453, Length=291, Percent_Identity=29.2096219931272, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64217; Mature: 64086

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSI
CCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLLMLRRHEKDYLARRSEKYLTSFDATYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SQYQTQFHQLAAQLANIDALQSELFAARSMLKTNVLSANDGELTAQFLQLLDHDLTFVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEC
PTQEHKVALLEGLSQFAKFEADLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HKTEQAITDLQTTIKQGVEQTAADIRSHLQWMGVVIVVLLSSLLYVIGRSILSRIKAINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDDIANGSGDLTVRMNAKGSDELAQLSRSFDLFISHLHDNIKQLASVMDVLGESSCSSE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QAAQRSMQNAQRVNSEADKALQLTHATGKRIDTLAISIEESQAQIQALEAQSREINAVVS
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHEEEEEHHHHHHHHHHHHHHHHHHHHHH
AIQGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
GIAQTVNKMADSVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQIATASEEQSMVSAE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
IDRNITQIAQLAGDTYEIVSGSVRCSEQVSDVSHKLEKIVAQFKY
HHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSI
CCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLLMLRRHEKDYLARRSEKYLTSFDATYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SQYQTQFHQLAAQLANIDALQSELFAARSMLKTNVLSANDGELTAQFLQLLDHDLTFVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEC
PTQEHKVALLEGLSQFAKFEADLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HKTEQAITDLQTTIKQGVEQTAADIRSHLQWMGVVIVVLLSSLLYVIGRSILSRIKAINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDDIANGSGDLTVRMNAKGSDELAQLSRSFDLFISHLHDNIKQLASVMDVLGESSCSSE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QAAQRSMQNAQRVNSEADKALQLTHATGKRIDTLAISIEESQAQIQALEAQSREINAVVS
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHEEEEEHHHHHHHHHHHHHHHHHHHHHH
AIQGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
GIAQTVNKMADSVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQIATASEEQSMVSAE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
IDRNITQIAQLAGDTYEIVSGSVRCSEQVSDVSHKLEKIVAQFKY
HHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]