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The map label for this gene is hpaG [H]

Identifier: 37679767

GI number: 37679767

Start: 1625598

End: 1626245

Strand: Direct

Name: hpaG [H]

Synonym: VV1583

Alternate gene names: 37679767

Gene position: 1625598-1626245 (Clockwise)

Preceding gene: 37679766

Following gene: 37679768

Centisome position: 48.46

GC content: 48.3

Gene sequence:

>648_bases
ATGAATACACAACTACAAGGAAAAGTGGTGTGCGTGGCGCTAAATGACGCTGAGCAACTGCAATCAATGAAGGCCACCTT
TGAACAAGCGCCATACAAAGCGTTACCGACTCAACCGGTACTCTACTTTAAACCGCATAACACGTGGAATCACGCCCAAC
AGCCGATCGCGTATCCAAAAGGGGACGAATTAGTTGTCGGTGCAAGTGTCGCATTGATTGTTGGCGAGCGTTGCTGCCGC
GTGAATGCTCAGTCTGCATTGGATTATGTCGCAGGAGTGGCTCTGCTACATGATTTTTCTCTGCCAGAAACCAGCTACTA
CCGCCCAGATATTAAGGGTAAGTGCCTCGACAACTCAGCAACACTAAGCCAAGCGCTCATGCTGTCTGATATCGGTGATT
TGTCACAACAGACTGTGACCACTTATATCAATGACAAGCAAGTGCAATCACTGCCGTTATCGCGCCTTGAACGTTCAGCA
GAACAGTTAATTGAGTTGATTTCACACATCATGACGCTAGAAAAAGGCGATGTGATCGCAATTGGCTTTGCAGGAGAAAG
AACCAAGCTTTCACCGGGTTATGTGGTGCGCTCAGCGTTGGGCGAGTCAGTCGAGTTGGAGAATCAAGTAAAAGGAGAGG
CAGCATGA

Upstream 100 bases:

>100_bases
AGAATCACTCGCGCAGTCGCTGAAACAGCCGTTATCTGAATCGAACAAGCTCGTCGACAACGTTTATTAATTCGTAGAGT
CAGAAACTAGAGAACAAATA

Downstream 100 bases:

>100_bases
AACGCGCACGTATTGAATATTTGGGAGATGTGCTGTCCGTTACAATTGGCGATGGTGACAATGCGATAACTGCAGATGGT
CGCTCGCTTCCGGCAGGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; HHDD isomerase; 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; OPET decarboxylase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNTQLQGKVVCVALNDAEQLQSMKATFEQAPYKALPTQPVLYFKPHNTWNHAQQPIAYPKGDELVVGASVALIVGERCCR
VNAQSALDYVAGVALLHDFSLPETSYYRPDIKGKCLDNSATLSQALMLSDIGDLSQQTVTTYINDKQVQSLPLSRLERSA
EQLIELISHIMTLEKGDVIAIGFAGERTKLSPGYVVRSALGESVELENQVKGEAA

Sequences:

>Translated_215_residues
MNTQLQGKVVCVALNDAEQLQSMKATFEQAPYKALPTQPVLYFKPHNTWNHAQQPIAYPKGDELVVGASVALIVGERCCR
VNAQSALDYVAGVALLHDFSLPETSYYRPDIKGKCLDNSATLSQALMLSDIGDLSQQTVTTYINDKQVQSLPLSRLERSA
EQLIELISHIMTLEKGDVIAIGFAGERTKLSPGYVVRSALGESVELENQVKGEAA
>Mature_215_residues
MNTQLQGKVVCVALNDAEQLQSMKATFEQAPYKALPTQPVLYFKPHNTWNHAQQPIAYPKGDELVVGASVALIVGERCCR
VNAQSALDYVAGVALLHDFSLPETSYYRPDIKGKCLDNSATLSQALMLSDIGDLSQQTVTTYINDKQVQSLPLSRLERSA
EQLIELISHIMTLEKGDVIAIGFAGERTKLSPGYVVRSALGESVELENQVKGEAA

Specific function: Decarboxylates OPET (5-oxo-pent-3-ene-1,2,5- tricarboxylic acid) into HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) and isomerizes it to OHED (2-oxo-hept-3-ene-1,7-dioate) [H]

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012684
- InterPro:   IPR012686 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =5.3.3.10; =4.1.1.68 [H]

Molecular weight: Translated: 23465; Mature: 23465

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQLQGKVVCVALNDAEQLQSMKATFEQAPYKALPTQPVLYFKPHNTWNHAQQPIAYPK
CCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDELVVGASVALIVGERCCRVNAQSALDYVAGVALLHDFSLPETSYYRPDIKGKCLDNSA
CCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHH
TLSQALMLSDIGDLSQQTVTTYINDKQVQSLPLSRLERSAEQLIELISHIMTLEKGDVIA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IGFAGERTKLSPGYVVRSALGESVELENQVKGEAA
EEECCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MNTQLQGKVVCVALNDAEQLQSMKATFEQAPYKALPTQPVLYFKPHNTWNHAQQPIAYPK
CCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDELVVGASVALIVGERCCRVNAQSALDYVAGVALLHDFSLPETSYYRPDIKGKCLDNSA
CCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHH
TLSQALMLSDIGDLSQQTVTTYINDKQVQSLPLSRLERSAEQLIELISHIMTLEKGDVIA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IGFAGERTKLSPGYVVRSALGESVELENQVKGEAA
EEECCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA