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The map label for this gene is hpcG [H]

Identifier: 37679765

GI number: 37679765

Start: 1623952

End: 1624755

Strand: Direct

Name: hpcG [H]

Synonym: VV1581

Alternate gene names: 37679765

Gene position: 1623952-1624755 (Clockwise)

Preceding gene: 37679764

Following gene: 37679766

Centisome position: 48.41

GC content: 50.5

Gene sequence:

>804_bases
ATGTTAACAAAGGAGCAGTTGCAAGAAGCGGCTGAACGACTGTACCACGCGGAAAAACAGCGTGAACAAATCTCTGCGCT
AACGCTGCAGTACCCAGAAATGACGATGGATGATGCTTACCAAATTCAGAGCGAGTGGGTAGGACGCAAGGTGAGCGAAG
GGGCTCAGGTCAAAGGATATAAAATCGGCTTAACGTCTCGCGCTATGCAAATGGCGGTCAATATTGACCAGCCTGACTAC
GGCGTACTGCTTGACGATATGTTCTTCCCTGATGGCGCGCAGATTAAAGCGGATGACTTCCTTGATCCCCGTATTGAAGT
GGAGTTGGCATTTGTCCTCAAAGAAAAGTTGGAAGGTGACGGCGTCACCATTTTCGATGTGCTTAACGCCACGGACTATG
TTGTACCTGCATTAGAGCTTATTGCTGCGCGTTGCCATCGTACCGATCCGAACACGGGTTACACCCGCAAAGTCTACGAC
ACCATCGCTGATAACGCAGCCAATGCTGGGATCATCTTAGGCGGTAGACCAATCAAACCAACGGAGTTCGATTTACGTTG
GGCGGGCGCGATGCTCTATCTCAACGGTCAAATTGAAGAGACTGGCTTAGCGGCAGGAGTATTGGGCCATCCGGCTAACG
GCATTTGCTGGGTATGTAAACGTTTTGCGCCACATGGTGTTTCTCTTGAACCAGGACAAGTGATTCTAGCGGGTTCATTT
ACTAGACCCGTCGCGGTTAAAGCAGGCGACACGATCCACGCTGATTTTGGTCCGCTTGGCGGCATTTCAGTGAAGTTTGT
GTAG

Upstream 100 bases:

>100_bases
CATGTTAATTAAGTTCGTCGGCTAGTAGCACGATACACATGCGCCAGAATGAGCGAGTAGCGATAACAAATGTCGGTCGA
TATAGAAAAAGGAAAACAGA

Downstream 100 bases:

>100_bases
AGGTGGCTATGTTACCGATTAACCAATTTAAGCAGCAATTGCATGAGCCTCAGACTCTTTGGGGATTATGGCTTGGTCTG
CCAGATACCAGCTGCGCGGA

Product: 2-keto-4-pentenoate hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLTKEQLQEAAERLYHAEKQREQISALTLQYPEMTMDDAYQIQSEWVGRKVSEGAQVKGYKIGLTSRAMQMAVNIDQPDY
GVLLDDMFFPDGAQIKADDFLDPRIEVELAFVLKEKLEGDGVTIFDVLNATDYVVPALELIAARCHRTDPNTGYTRKVYD
TIADNAANAGIILGGRPIKPTEFDLRWAGAMLYLNGQIEETGLAAGVLGHPANGICWVCKRFAPHGVSLEPGQVILAGSF
TRPVAVKAGDTIHADFGPLGGISVKFV

Sequences:

>Translated_267_residues
MLTKEQLQEAAERLYHAEKQREQISALTLQYPEMTMDDAYQIQSEWVGRKVSEGAQVKGYKIGLTSRAMQMAVNIDQPDY
GVLLDDMFFPDGAQIKADDFLDPRIEVELAFVLKEKLEGDGVTIFDVLNATDYVVPALELIAARCHRTDPNTGYTRKVYD
TIADNAANAGIILGGRPIKPTEFDLRWAGAMLYLNGQIEETGLAAGVLGHPANGICWVCKRFAPHGVSLEPGQVILAGSF
TRPVAVKAGDTIHADFGPLGGISVKFV
>Mature_267_residues
MLTKEQLQEAAERLYHAEKQREQISALTLQYPEMTMDDAYQIQSEWVGRKVSEGAQVKGYKIGLTSRAMQMAVNIDQPDY
GVLLDDMFFPDGAQIKADDFLDPRIEVELAFVLKEKLEGDGVTIFDVLNATDYVVPALELIAARCHRTDPNTGYTRKVYD
TIADNAANAGIILGGRPIKPTEFDLRWAGAMLYLNGQIEETGLAAGVLGHPANGICWVCKRFAPHGVSLEPGQVILAGSF
TRPVAVKAGDTIHADFGPLGGISVKFV

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=265, Percent_Identity=33.2075471698113, Blast_Score=148, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 29215; Mature: 29215

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKEQLQEAAERLYHAEKQREQISALTLQYPEMTMDDAYQIQSEWVGRKVSEGAQVKGY
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCHHCCCCEECEE
KIGLTSRAMQMAVNIDQPDYGVLLDDMFFPDGAQIKADDFLDPRIEVELAFVLKEKLEGD
EEECHHHEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEEEEEEHHHCCCC
GVTIFDVLNATDYVVPALELIAARCHRTDPNTGYTRKVYDTIADNAANAGIILGGRPIKP
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
TEFDLRWAGAMLYLNGQIEETGLAAGVLGHPANGICWVCKRFAPHGVSLEPGQVILAGSF
CCCCEEEEEEEEEECCCCCCCCCEEHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECC
TRPVAVKAGDTIHADFGPLGGISVKFV
CCCEEEECCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MLTKEQLQEAAERLYHAEKQREQISALTLQYPEMTMDDAYQIQSEWVGRKVSEGAQVKGY
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCHHCCCCEECEE
KIGLTSRAMQMAVNIDQPDYGVLLDDMFFPDGAQIKADDFLDPRIEVELAFVLKEKLEGD
EEECHHHEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEEEEEEHHHCCCC
GVTIFDVLNATDYVVPALELIAARCHRTDPNTGYTRKVYDTIADNAANAGIILGGRPIKP
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCC
TEFDLRWAGAMLYLNGQIEETGLAAGVLGHPANGICWVCKRFAPHGVSLEPGQVILAGSF
CCCCEEEEEEEEEECCCCCCCCCEEHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECC
TRPVAVKAGDTIHADFGPLGGISVKFV
CCCEEEECCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]