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The map label for this gene is tag [H]

Identifier: 37679582

GI number: 37679582

Start: 1423051

End: 1423620

Strand: Direct

Name: tag [H]

Synonym: VV1398

Alternate gene names: 37679582

Gene position: 1423051-1423620 (Clockwise)

Preceding gene: 37679581

Following gene: 37679585

Centisome position: 42.42

GC content: 46.84

Gene sequence:

>570_bases
ATGATGGCAGAACAAAAAACATGTGCGTGGGCGATGAATCACCCTTTAGAGCGTGAATATCATGACGCGGAATGGGGTAA
GCCTGTTTACGACGACAGCATACTTTTTGAGTTCATTACGCTAGAAGGTGCACAGGCAGGATTGAGTTGGATTACGATTC
TGAAAAAACGTCAGGGTTATCGAGAGGCATTTGAAGGCTATGACCTCAAACGACTCGCGCAACAGGGAGAGCAAAGGGTT
GAGGCGATCATCGCTCAGTACGATGTGGTGAAACATCGTGGGAAAATTGCGTCGGTGTTTAGTAATGCACGCGCTGCATT
GGCGCTTCAAGAAGAGTTTGGTTCACTGTCTAACGCTTTGTGGTTGTTTGTCGACCATCAGCCGATTGTTAACCAATGGC
AATCGATGGATGAAGTGCCCGCGGTCACGGAGCAATCCAAAGCGCTCAGCAAGTTTCTTAAAAAGCGTGGCTTTAAGTTT
GTTGGAGAAACCATTTGCTATGCCTTCATGCAAGCGGTCGGGATGGTTGATGATCATTTAATTGATTGCCCCTGTAAAGC
ACATCGATAA

Upstream 100 bases:

>100_bases
GTTGTATCGTCTCTTCCACAAAGTGGCGGTGCCGAAATAATTAATCGGTCTAGGAATCTAAACGCCTTCACCTTGTGAGG
GCGTTTTTATAAGGATTTAG

Downstream 100 bases:

>100_bases
AAAACAGCCCCGCAGAGATGAGGGGCTGTTTTATATGCATAGCGGGGAGCGCCTAACGAGGTAAATCGCCGCTAGCTAAG
AGAGGTTTCTCTTTCAAGAA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosidase; TAG [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMAEQKTCAWAMNHPLEREYHDAEWGKPVYDDSILFEFITLEGAQAGLSWITILKKRQGYREAFEGYDLKRLAQQGEQRV
EAIIAQYDVVKHRGKIASVFSNARAALALQEEFGSLSNALWLFVDHQPIVNQWQSMDEVPAVTEQSKALSKFLKKRGFKF
VGETICYAFMQAVGMVDDHLIDCPCKAHR

Sequences:

>Translated_189_residues
MMAEQKTCAWAMNHPLEREYHDAEWGKPVYDDSILFEFITLEGAQAGLSWITILKKRQGYREAFEGYDLKRLAQQGEQRV
EAIIAQYDVVKHRGKIASVFSNARAALALQEEFGSLSNALWLFVDHQPIVNQWQSMDEVPAVTEQSKALSKFLKKRGFKF
VGETICYAFMQAVGMVDDHLIDCPCKAHR
>Mature_189_residues
MMAEQKTCAWAMNHPLEREYHDAEWGKPVYDDSILFEFITLEGAQAGLSWITILKKRQGYREAFEGYDLKRLAQQGEQRV
EAIIAQYDVVKHRGKIASVFSNARAALALQEEFGSLSNALWLFVDHQPIVNQWQSMDEVPAVTEQSKALSKFLKKRGFKF
VGETICYAFMQAVGMVDDHLIDCPCKAHR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=178, Percent_Identity=50, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21618; Mature: 21618

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAEQKTCAWAMNHPLEREYHDAEWGKPVYDDSILFEFITLEGAQAGLSWITILKKRQGY
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
REAFEGYDLKRLAQQGEQRVEAIIAQYDVVKHRGKIASVFSNARAALALQEEFGSLSNAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEE
WLFVDHQPIVNQWQSMDEVPAVTEQSKALSKFLKKRGFKFVGETICYAFMQAVGMVDDHL
EEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IDCPCKAHR
CCCCCCCCC
>Mature Secondary Structure
MMAEQKTCAWAMNHPLEREYHDAEWGKPVYDDSILFEFITLEGAQAGLSWITILKKRQGY
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
REAFEGYDLKRLAQQGEQRVEAIIAQYDVVKHRGKIASVFSNARAALALQEEFGSLSNAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEE
WLFVDHQPIVNQWQSMDEVPAVTEQSKALSKFLKKRGFKFVGETICYAFMQAVGMVDDHL
EEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IDCPCKAHR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]