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The map label for this gene is pspA [H]

Identifier: 37679576

GI number: 37679576

Start: 1416306

End: 1416977

Strand: Direct

Name: pspA [H]

Synonym: VV1392

Alternate gene names: 37679576

Gene position: 1416306-1416977 (Clockwise)

Preceding gene: 37679568

Following gene: 37679577

Centisome position: 42.22

GC content: 44.35

Gene sequence:

>672_bases
ATGGGTATTTTTTCTCGTTTTGCAGACATCATCAATTCCAATATCAGTGCGCTGCTGGATAAAGCAGAAGATCCGGAAAA
AATGATTCGTCTCATCATTCAAGAAATGGAAGACACGCTGGTCGAAGTGCGTACCAACTCGGCGAAAGCCATTGCGGATA
AAAAAGAGCTCGCTCGTAAAGTGGAAGCAATGGAAAGCCAAATTTCGGATTGGCAACAAAAAGCGACATTGGCGCTGACG
AAGCAACGTGAAGATTTGGCGCGTGCAGCATTAATTGAAAAGCAAAAGCTACAAGACTTGATCAAAGGTTTGCATACAGA
GCAAACTCTTGTGGAAGAAACCATTGAGAAACTGACTGGCGAAATTGGCAAATTGGAAACCAAAATTGCCGAAACGCGCG
CGAAGCAGCAAGCTTTGATGATCCGCAATCAAACGGCTTCCAATCGTCGTGATGTTCAGCGTCATTTGAGCTCCGGCCGC
ACGCATGAAGCGATGGCAAAGTTTGAGCAATACGCTCGTAAAGTGGATGAGCTGGAAGCCGAAGCGGATCTCTACGCCAA
CTCAGGTTCATCAAAATCATTGGAACAGGAATTTGCTGAGCTTCAAGCTCAGGATGAAATTGAAAAAGAGTTGGCAAAGT
TAAAAGAACAAGTGAACTCACAACAAAAATAA

Upstream 100 bases:

>100_bases
ACTTTGGCATGCTTCTTGTTATAACGTAAATAACTAGAACACTGACTGAGTGCATTTTTAGATAAAAGCACGATATCGAG
ACTAATAGAGGAGTTCCATC

Downstream 100 bases:

>100_bases
GCAAAGGAGCCATCTATGACGACATTTATGATTGCAGGGCCATTAATCGTATTTCTGATTTTTGTCGCACCACTGTGGCT
ATTTCTTCACTATCGCAGTC

Product: phage shock protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MGIFSRFADIINSNISALLDKAEDPEKMIRLIIQEMEDTLVEVRTNSAKAIADKKELARKVEAMESQISDWQQKATLALT
KQREDLARAALIEKQKLQDLIKGLHTEQTLVEETIEKLTGEIGKLETKIAETRAKQQALMIRNQTASNRRDVQRHLSSGR
THEAMAKFEQYARKVDELEAEADLYANSGSSKSLEQEFAELQAQDEIEKELAKLKEQVNSQQK

Sequences:

>Translated_223_residues
MGIFSRFADIINSNISALLDKAEDPEKMIRLIIQEMEDTLVEVRTNSAKAIADKKELARKVEAMESQISDWQQKATLALT
KQREDLARAALIEKQKLQDLIKGLHTEQTLVEETIEKLTGEIGKLETKIAETRAKQQALMIRNQTASNRRDVQRHLSSGR
THEAMAKFEQYARKVDELEAEADLYANSGSSKSLEQEFAELQAQDEIEKELAKLKEQVNSQQK
>Mature_222_residues
GIFSRFADIINSNISALLDKAEDPEKMIRLIIQEMEDTLVEVRTNSAKAIADKKELARKVEAMESQISDWQQKATLALTK
QREDLARAALIEKQKLQDLIKGLHTEQTLVEETIEKLTGEIGKLETKIAETRAKQQALMIRNQTASNRRDVQRHLSSGRT
HEAMAKFEQYARKVDELEAEADLYANSGSSKSLEQEFAELQAQDEIEKELAKLKEQVNSQQK

Specific function: The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation

COG id: COG1842

COG function: function code KT; Phage shock protein A (IM30), suppresses sigma54-dependent transcription

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PspA/IM30 family [H]

Homologues:

Organism=Escherichia coli, GI2367118, Length=215, Percent_Identity=60.4651162790698, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014319
- InterPro:   IPR007157 [H]

Pfam domain/function: PF04012 PspA_IM30 [H]

EC number: NA

Molecular weight: Translated: 25354; Mature: 25223

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIFSRFADIINSNISALLDKAEDPEKMIRLIIQEMEDTLVEVRTNSAKAIADKKELARK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VEAMESQISDWQQKATLALTKQREDLARAALIEKQKLQDLIKGLHTEQTLVEETIEKLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
EIGKLETKIAETRAKQQALMIRNQTASNRRDVQRHLSSGRTHEAMAKFEQYARKVDELEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EADLYANSGSSKSLEQEFAELQAQDEIEKELAKLKEQVNSQQK
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIFSRFADIINSNISALLDKAEDPEKMIRLIIQEMEDTLVEVRTNSAKAIADKKELARK
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VEAMESQISDWQQKATLALTKQREDLARAALIEKQKLQDLIKGLHTEQTLVEETIEKLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
EIGKLETKIAETRAKQQALMIRNQTASNRRDVQRHLSSGRTHEAMAKFEQYARKVDELEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EADLYANSGSSKSLEQEFAELQAQDEIEKELAKLKEQVNSQQK
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]