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The map label for this gene is ptsG [H]

Identifier: 37679467

GI number: 37679467

Start: 1302944

End: 1304467

Strand: Direct

Name: ptsG [H]

Synonym: VV1283

Alternate gene names: 37679467

Gene position: 1302944-1304467 (Clockwise)

Preceding gene: 37679466

Following gene: 37679468

Centisome position: 38.84

GC content: 46.72

Gene sequence:

>1524_bases
ATGTGGTTACATTTTCATAGGGTGCTAACATTTAGGCTACGGGGGTGTGCCGTTAGAACCCAAAATACTAATAAATTAAT
CAGGAGCATAAACATGTTTAAGAACCTTTTTGCTAACCTGCAAAAAGTTGGTAAAGCGCTGATGCTACCAGTATCAGTTT
TACCAGTTGCGGGTATTCTACTAGGTGTGGGTGCTGCCGACCTTAGCTTCATTCCAGATATCGTATCAAATCTGATGGAG
CAGGCGGGTGGTTCTGTATTTGGTCAAATGGCACTACTATTTGCTGTAGGTGTTGCACTTGGCTTTACAAATAATGACGG
CGTAGCAGGTCTAGCTGCGATCGTTGGTTACGGCATCATGACAGCAACACTTGCAGTTATGGCTGGCGTAATGGGCGTTG
AAAAAATCGACACAGGTGTCCTTGGTGGTATCCTAGTCGGTGGTGTTGCTGCTTGGGCATTCAACCGTTTCTTCAAGATT
CAACTACCAGAATACCTAGGCTTCTTTGCTGGTAAGCGTGCTGTGCCAATCATCACTGGTTTCACGGCTATCGCTCTTGG
TATCCTACTATCAATCGTATGGCCTCCAATCGGTGGTGCTATTGCTTCTTTCTCTGATTGGGCTGCTCATCAGAACCCAC
AAGTTGCATTCGGTATCTACGGTATTGTTGAACGTTCTCTTATCCCATTCGGTCTACACCACGTGTGGAACGTACCATTC
TTCTTCGAAGCGGGTAGCTGTGTGAACGCTGCAGGCGAAGCTCAAAATGGTGTTCTAACGTGTTACCTAGTTGCAGATGA
AGCTTCTCGTGCTGCGGGCAATGGCTTTGGTCAGCTAGCGGGTGGTTACATGTTCAAGATGTTTGGTCTACCAGCAGCAG
CGATCGCTATCGCACACTGTGCTAAGCCAGAGAACCGCGCGAAAGTAATGGGTATCATGGCGTCAGCAGCTCTGACTTCA
TTCCTAACCGGTATTACTGAGCCAATCGAATTCTCATTCCTATTCGTTGCTCCTGTACTTTACGGTATCCACGCTCTACT
AGCGGGTTCTGCATACGTTGTTGCTAACACTCTAGGTTTTGTACACGGTACTTCATTCTCTCACGGTCTGATTGACTTCC
TAGTTCTATCTGGTAACGCGCAGAAGATGGGTCTGATGATTGGTGTTGGTCTCGTTTACGCAGTTATCTACTACGTAGTA
TTCCGCTTCGTTATTCAAGCGATGGATCTTAAGACTCCAGGTCGTGAAGATGAAACGGAAGAAGCAACAGCGACTTCTGG
TTCAGACCTTGCTGGTGAATTGGTTGCTGCGTTCGGCGGTAAAGCAAACATCACAGGTCTAGATGCATGTATCACTCGTC
TACGTGTGGCTGTTGCTGACACAGCAGCGGTAGACCAAGATAAATTGAAGAAGCTAGGTGCAGCAGGTGTTGTTGTTGTT
GCTGGTGGTGTTCAAGCTATCTTCGGTACTAAATCTGACAACCTAAAAACTGAAATGGATGAGTGGATCCGTAACCACGG
TTAA

Upstream 100 bases:

>100_bases
TGTGTGTGATCCGTGACTTGTTTTGAAACTAATTTTCGTAACTCTGTAGAAAGTTTGAGGGGCATCAAGATATATTTAGA
GGCGGAAAATATAATGCAAC

Downstream 100 bases:

>100_bases
TCCCTAACACTCATTGATTGACAAAAGGAGGCTGAGGCCTCCTTTTTTATTGTTTCTTTCCTACTTGAAGCTGCAGCGAT
CAGGCTACGTTTGTTCACTG

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MWLHFHRVLTFRLRGCAVRTQNTNKLIRSINMFKNLFANLQKVGKALMLPVSVLPVAGILLGVGAADLSFIPDIVSNLME
QAGGSVFGQMALLFAVGVALGFTNNDGVAGLAAIVGYGIMTATLAVMAGVMGVEKIDTGVLGGILVGGVAAWAFNRFFKI
QLPEYLGFFAGKRAVPIITGFTAIALGILLSIVWPPIGGAIASFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPF
FFEAGSCVNAAGEAQNGVLTCYLVADEASRAAGNGFGQLAGGYMFKMFGLPAAAIAIAHCAKPENRAKVMGIMASAALTS
FLTGITEPIEFSFLFVAPVLYGIHALLAGSAYVVANTLGFVHGTSFSHGLIDFLVLSGNAQKMGLMIGVGLVYAVIYYVV
FRFVIQAMDLKTPGREDETEEATATSGSDLAGELVAAFGGKANITGLDACITRLRVAVADTAAVDQDKLKKLGAAGVVVV
AGGVQAIFGTKSDNLKTEMDEWIRNHG

Sequences:

>Translated_507_residues
MWLHFHRVLTFRLRGCAVRTQNTNKLIRSINMFKNLFANLQKVGKALMLPVSVLPVAGILLGVGAADLSFIPDIVSNLME
QAGGSVFGQMALLFAVGVALGFTNNDGVAGLAAIVGYGIMTATLAVMAGVMGVEKIDTGVLGGILVGGVAAWAFNRFFKI
QLPEYLGFFAGKRAVPIITGFTAIALGILLSIVWPPIGGAIASFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPF
FFEAGSCVNAAGEAQNGVLTCYLVADEASRAAGNGFGQLAGGYMFKMFGLPAAAIAIAHCAKPENRAKVMGIMASAALTS
FLTGITEPIEFSFLFVAPVLYGIHALLAGSAYVVANTLGFVHGTSFSHGLIDFLVLSGNAQKMGLMIGVGLVYAVIYYVV
FRFVIQAMDLKTPGREDETEEATATSGSDLAGELVAAFGGKANITGLDACITRLRVAVADTAAVDQDKLKKLGAAGVVVV
AGGVQAIFGTKSDNLKTEMDEWIRNHG
>Mature_507_residues
MWLHFHRVLTFRLRGCAVRTQNTNKLIRSINMFKNLFANLQKVGKALMLPVSVLPVAGILLGVGAADLSFIPDIVSNLME
QAGGSVFGQMALLFAVGVALGFTNNDGVAGLAAIVGYGIMTATLAVMAGVMGVEKIDTGVLGGILVGGVAAWAFNRFFKI
QLPEYLGFFAGKRAVPIITGFTAIALGILLSIVWPPIGGAIASFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPF
FFEAGSCVNAAGEAQNGVLTCYLVADEASRAAGNGFGQLAGGYMFKMFGLPAAAIAIAHCAKPENRAKVMGIMASAALTS
FLTGITEPIEFSFLFVAPVLYGIHALLAGSAYVVANTLGFVHGTSFSHGLIDFLVLSGNAQKMGLMIGVGLVYAVIYYVV
FRFVIQAMDLKTPGREDETEEATATSGSDLAGELVAAFGGKANITGLDACITRLRVAVADTAAVDQDKLKKLGAAGVVVV
AGGVQAIFGTKSDNLKTEMDEWIRNHG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=484, Percent_Identity=66.5289256198347, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1786894, Length=480, Percent_Identity=39.5833333333333, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=34.6820809248555, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 53192; Mature: 53192

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLHFHRVLTFRLRGCAVRTQNTNKLIRSINMFKNLFANLQKVGKALMLPVSVLPVAGIL
CCEEHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVGAADLSFIPDIVSNLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGLAAIVGYGIM
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TATLAVMAGVMGVEKIDTGVLGGILVGGVAAWAFNRFFKIQLPEYLGFFAGKRAVPIITG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCCHHHHH
FTAIALGILLSIVWPPIGGAIASFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPF
HHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCCCEEEHHHHHHHHHHCHHHHHHHHCCCE
FFEAGSCVNAAGEAQNGVLTCYLVADEASRAAGNGFGQLAGGYMFKMFGLPAAAIAIAHC
EEECCCHHCCCCCCCCCEEEEEEEECCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
AKPENRAKVMGIMASAALTSFLTGITEPIEFSFLFVAPVLYGIHALLAGSAYVVANTLGF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VHGTSFSHGLIDFLVLSGNAQKMGLMIGVGLVYAVIYYVVFRFVIQAMDLKTPGREDETE
HCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EATATSGSDLAGELVAAFGGKANITGLDACITRLRVAVADTAAVDQDKLKKLGAAGVVVV
HHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEE
AGGVQAIFGTKSDNLKTEMDEWIRNHG
ECCHHEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MWLHFHRVLTFRLRGCAVRTQNTNKLIRSINMFKNLFANLQKVGKALMLPVSVLPVAGIL
CCEEHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVGAADLSFIPDIVSNLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGLAAIVGYGIM
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TATLAVMAGVMGVEKIDTGVLGGILVGGVAAWAFNRFFKIQLPEYLGFFAGKRAVPIITG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCCHHHHH
FTAIALGILLSIVWPPIGGAIASFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPF
HHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCCCEEEHHHHHHHHHHCHHHHHHHHCCCE
FFEAGSCVNAAGEAQNGVLTCYLVADEASRAAGNGFGQLAGGYMFKMFGLPAAAIAIAHC
EEECCCHHCCCCCCCCCEEEEEEEECCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
AKPENRAKVMGIMASAALTSFLTGITEPIEFSFLFVAPVLYGIHALLAGSAYVVANTLGF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VHGTSFSHGLIDFLVLSGNAQKMGLMIGVGLVYAVIYYVVFRFVIQAMDLKTPGREDETE
HCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EATATSGSDLAGELVAAFGGKANITGLDACITRLRVAVADTAAVDQDKLKKLGAAGVVVV
HHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEE
AGGVQAIFGTKSDNLKTEMDEWIRNHG
ECCHHEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]