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The map label for this gene is ycfH [C]

Identifier: 37679466

GI number: 37679466

Start: 1301826

End: 1302593

Strand: Direct

Name: ycfH [C]

Synonym: VV1282

Alternate gene names: 37679466

Gene position: 1301826-1302593 (Clockwise)

Preceding gene: 37679465

Following gene: 37679467

Centisome position: 38.81

GC content: 44.01

Gene sequence:

>768_bases
ATGTTTGTAGATTCTCATTGTCACCTAGACAAATTGAATTACGATGATCTGCACATAGATGTTGCTGACGTGATCAACAA
AGCCAAGCAGGTAAATGTGGAGCAATTGCTGTCTGTCGGTGTGACATTGGATTCTTTTCCAAAAATGCTTGAGCTCATTG
AGCCTTTTGACAACGTACACGCCTCTTGTGGAGTGCACCCATTAGACGTGGAAAGTCCCTTTTGCTTGGACAAAATGAAA
GCCTATGCCTCGCATTCTAAAGTTGTGGCTATTGGTGAAACGGGTCTTGATTATCACTATAAGCCAGAGACGCAAGCATT
GCAGCGTGAACGTTTTGAACAGCAAGTTGCACTCGCGGTTGAGCTGAATAAGCCACTGATTATCCATACGAGGCAAGCGA
GAGAAGATACCTTAGCCATTCTTCGCAATGGGGGGGCAGACAAATGCGGTGGCGTGATTCACTGTTTTACCGAAGATCTT
GCTTTTGCTGAAGCGGCAATGGCGCTCGGTTTTTACATCTCTATCTCTGGAATTGTCACGTTCAGACAAGCAACGGAGCT
TAAAGAGGTTGTAAAACACATTCCTTTGGAACGGTTGTTGATCGAAACCGATTCTCCGTACTTGGCACCTGTACCTCATA
GGGGCAAAGAGAATCAACCCGCCTATGTTATCGAAGTTGCTGCATATATCGCACAGCTTAAAAACATTTCCTTAGCAAGT
GTTGGTGAAAAAACCACCCAAAACTTTAAAAATCTTTTTTTGCGATAG

Upstream 100 bases:

>100_bases
TGGTAAAACTCAATCAATTAAATCAACAGTTACATCAGTTTTCGGGTTTAAACGAAGAACTGATGATCATCAACTGGTTA
ATCGAAACTAGAGAGGCATT

Downstream 100 bases:

>100_bases
AAAAAGAAATATTGATTAAAAAGAGAGCAAATGCTCTCTTTTTTTATTTTTAACCCCATAAAGTAAATTAATTTTTCTTG
TTAACTAAATCTGTTGATTG

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFVDSHCHLDKLNYDDLHIDVADVINKAKQVNVEQLLSVGVTLDSFPKMLELIEPFDNVHASCGVHPLDVESPFCLDKMK
AYASHSKVVAIGETGLDYHYKPETQALQRERFEQQVALAVELNKPLIIHTRQAREDTLAILRNGGADKCGGVIHCFTEDL
AFAEAAMALGFYISISGIVTFRQATELKEVVKHIPLERLLIETDSPYLAPVPHRGKENQPAYVIEVAAYIAQLKNISLAS
VGEKTTQNFKNLFLR

Sequences:

>Translated_255_residues
MFVDSHCHLDKLNYDDLHIDVADVINKAKQVNVEQLLSVGVTLDSFPKMLELIEPFDNVHASCGVHPLDVESPFCLDKMK
AYASHSKVVAIGETGLDYHYKPETQALQRERFEQQVALAVELNKPLIIHTRQAREDTLAILRNGGADKCGGVIHCFTEDL
AFAEAAMALGFYISISGIVTFRQATELKEVVKHIPLERLLIETDSPYLAPVPHRGKENQPAYVIEVAAYIAQLKNISLAS
VGEKTTQNFKNLFLR
>Mature_255_residues
MFVDSHCHLDKLNYDDLHIDVADVINKAKQVNVEQLLSVGVTLDSFPKMLELIEPFDNVHASCGVHPLDVESPFCLDKMK
AYASHSKVVAIGETGLDYHYKPETQALQRERFEQQVALAVELNKPLIIHTRQAREDTLAILRNGGADKCGGVIHCFTEDL
AFAEAAMALGFYISISGIVTFRQATELKEVVKHIPLERLLIETDSPYLAPVPHRGKENQPAYVIEVAAYIAQLKNISLAS
VGEKTTQNFKNLFLR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=32.7137546468402, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=33.2116788321168, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI110349734, Length=270, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=32.295719844358, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI225903424, Length=272, Percent_Identity=30.5147058823529, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=31.6017316017316, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI14042943, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI225903439, Length=133, Percent_Identity=36.0902255639098, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1787342, Length=253, Percent_Identity=53.7549407114625, Blast_Score=284, Evalue=4e-78,
Organism=Escherichia coli, GI48994985, Length=241, Percent_Identity=33.6099585062241, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=27.34375, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=29.1512915129151, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=26.2357414448669, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221330018, Length=212, Percent_Identity=34.4339622641509, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24586117, Length=212, Percent_Identity=34.4339622641509, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24648690, Length=199, Percent_Identity=31.6582914572864, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28454; Mature: 28454

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDSHCHLDKLNYDDLHIDVADVINKAKQVNVEQLLSVGVTLDSFPKMLELIEPFDNVH
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASCGVHPLDVESPFCLDKMKAYASHSKVVAIGETGLDYHYKPETQALQRERFEQQVALAV
HHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEE
ELNKPLIIHTRQAREDTLAILRNGGADKCGGVIHCFTEDLAFAEAAMALGFYISISGIVT
ECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEHHHH
FRQATELKEVVKHIPLERLLIETDSPYLAPVPHRGKENQPAYVIEVAAYIAQLKNISLAS
HHHHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VGEKTTQNFKNLFLR
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MFVDSHCHLDKLNYDDLHIDVADVINKAKQVNVEQLLSVGVTLDSFPKMLELIEPFDNVH
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ASCGVHPLDVESPFCLDKMKAYASHSKVVAIGETGLDYHYKPETQALQRERFEQQVALAV
HHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHEEEEE
ELNKPLIIHTRQAREDTLAILRNGGADKCGGVIHCFTEDLAFAEAAMALGFYISISGIVT
ECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEHHHH
FRQATELKEVVKHIPLERLLIETDSPYLAPVPHRGKENQPAYVIEVAAYIAQLKNISLAS
HHHHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
VGEKTTQNFKNLFLR
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]