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The map label for this gene is pgsA [H]

Identifier: 37679419

GI number: 37679419

Start: 1248973

End: 1249530

Strand: Direct

Name: pgsA [H]

Synonym: VV1235

Alternate gene names: 37679419

Gene position: 1248973-1249530 (Clockwise)

Preceding gene: 37679418

Following gene: 37679420

Centisome position: 37.23

GC content: 44.62

Gene sequence:

>558_bases
ATGCGTTTGAACATCCCCAACATATTGTCACTAATGAGATTATTTCTCATCCCAGTGTTTGTCGTTGCGTTTTATCTTCC
CTATTCATGGGCTCCTTTTGCTGCGGCAATGGTGTTTTGGGTTGCCGGTTTTACCGATTGGCTCGATGGGATGCTAGCAA
GAAAACTGGGTCAAACGTCTCGTTTTGGTGCGTTTATTGATCCAGTGGCGGATAAAGTACTAGTGGCAACCGCTTTGATT
TTGATTACAGAACATTACCATTCCATTTGGGTAACGATTCCAGCCGTGACCATGATCGCAAGGGAAATCATTATTTCAGC
ACTGCGTGAGTGGATGGCAGAGATCGGCAAACGAGCGAGCGTTGCTGTCTCTTGGGTCGGTAAAGTAAAAACCATGACTC
AAATGTTTGCGCTATGGGTATTAATTTGGCGTTATGACGATTGGATGGTTTGGTTAGGTTTCGGCGCATTGTACATTGCC
ACATTCCTTACTTACTGGTCGATGGTGCAGTACTTGATGGCTGCGAAAGATGACTTGTTGAATGAAGAACATCACTAA

Upstream 100 bases:

>100_bases
CCGGGCATCAGTCACTCTTTGGCAGAAATTATCTATCAAGCATTGAAACAATAGTGAAAATCCAGCACCATTAGCGCGCA
AAGTGTAAGAGAATAATAAT

Downstream 100 bases:

>100_bases
TGTTGAGAAAGCGGGCGCAAGCCCGTTTTTTTATGCGTGAAGTTCGCGAGCAAGGCGTAAGTATAAGTTGTGTAAGACAA
GGATTATTCTAGATAATCTT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRLNIPNILSLMRLFLIPVFVVAFYLPYSWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LITEHYHSIWVTIPAVTMIAREIIISALREWMAEIGKRASVAVSWVGKVKTMTQMFALWVLIWRYDDWMVWLGFGALYIA
TFLTYWSMVQYLMAAKDDLLNEEHH

Sequences:

>Translated_185_residues
MRLNIPNILSLMRLFLIPVFVVAFYLPYSWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LITEHYHSIWVTIPAVTMIAREIIISALREWMAEIGKRASVAVSWVGKVKTMTQMFALWVLIWRYDDWMVWLGFGALYIA
TFLTYWSMVQYLMAAKDDLLNEEHH
>Mature_185_residues
MRLNIPNILSLMRLFLIPVFVVAFYLPYSWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LITEHYHSIWVTIPAVTMIAREIIISALREWMAEIGKRASVAVSWVGKVKTMTQMFALWVLIWRYDDWMVWLGFGALYIA
TFLTYWSMVQYLMAAKDDLLNEEHH

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=182, Percent_Identity=64.2857142857143, Blast_Score=243, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21330; Mature: 21330

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNIPNILSLMRLFLIPVFVVAFYLPYSWAPFAAAMVFWVAGFTDWLDGMLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFIDPVADKVLVATALILITEHYHSIWVTIPAVTMIAREIIISALREWMAEIGKRAS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTMTQMFALWVLIWRYDDWMVWLGFGALYIATFLTYWSMVQYLMAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NEEHH
CCCCC
>Mature Secondary Structure
MRLNIPNILSLMRLFLIPVFVVAFYLPYSWAPFAAAMVFWVAGFTDWLDGMLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFIDPVADKVLVATALILITEHYHSIWVTIPAVTMIAREIIISALREWMAEIGKRAS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTMTQMFALWVLIWRYDDWMVWLGFGALYIATFLTYWSMVQYLMAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NEEHH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]