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The map label for this gene is gmr [H]

Identifier: 37679324

GI number: 37679324

Start: 1148842

End: 1150815

Strand: Direct

Name: gmr [H]

Synonym: VV1140

Alternate gene names: 37679324

Gene position: 1148842-1150815 (Clockwise)

Preceding gene: 37679323

Following gene: 37679326

Centisome position: 34.25

GC content: 45.49

Gene sequence:

>1974_bases
ATGATAAAAAAATTTGGTTGGCTGCTTTCCTGCGTATTCGTTTGGGTATCGTTCAACTGTTGGGCAAAGAGTAAAGAGAT
CACAGTAGCAACGGAAGCGGATGATGTGGTGACGCGTGTTCTGTTTGATGCCATTGCCGAGCAGTTTACGCTGGACGTCA
CCTATGTGAATATGCCGAGTTTTGATGCTATTCTCGATTCAGTCGCGCGTGGTGAAACAGACTTCGCAGCGAACATTACG
TTTACGCATGAACGTGAAAAAAGATTCAGTTATTCACACCCAACCAACATTGAATATACCTATCTCTATTCTAATACGAC
CAATTCGTTGCGTGATGCGACACGTATTGGTGTGCCTCAAGACACCATTTATGGGGAGCTGATTGCGGTAAATCATCCAG
ACATTCAGCTTGTTTCGTACCAAGGCCATGAAGAAGCTTATGCGCTGATCAGTCTCGGTCAAGTCGATGGCATTGTGGAT
GCCATCAATCAACTTAAGCCTATGTTGCTTAAAGGAACTAATGCCCATCTTCTCAACGATGAAATTTCGATAAAACCCGT
CTCTATCGTCAGTCAAAAAGGGCAACACTTAGAAGAGTTGACTCAATTTGCTCAGTTCATTCACAGCGAGCAGATGCAAA
AAAGGCTTCGTGAAGAAATTACGCAATACCAATTTGCTATTCGAAAACAGGCGCTACAACAGGCTATTGCTCAGGCACCC
CTTGATCTAGATGAACCATTAACCATCAAACTTGAGCCGATTTACCCCTATGTGATTTACCATCCTGATGGCCACGTGAG
TGGGATTACTGCCGAAGTTCTGCAGCAAAGTTGCGATATTCTTGCCCTTAACTGTCAACTGGTGAGCCGTTCAGATGAAC
GTTGGGGAGAAATGTTACAAGGCTTCATACAGCAAGAGTTTGACCTACTGGCTCCGCTGGCGATGACCAAAGCGAGAGAG
CAGTTTACCTATTACACAAGCCCACACTATGCGCCTCAGTCGGTTATCGTCAAACGTTTGGGGTATAAGCCCAATGTCTA
TTCTCATGTCTCCCAGTTAATTGCAGAGAGAGTCGGAGTGGTTGAGGATGACTACTTTGATGCGTTGTTGACGCAAATGT
TGCCATTGAAAGAGCTGAGTCGTTTTTCCGATCACGATGCGATGGTCAGAGCCTTACTTGCCAACCGAGTGGATTACATC
ACGATGGACACGGCAACACTCAACTACTTACTACGAAATGAGTTGAAGCTGGCTATTGAGCAAGATGATGCGATTGGCGT
ATTTGATGCGTCGAAAATTTCTATCGGTTTGGCTAACACGGAAAAGGGCAGAGTGCTGGCTCCGTATTTTAGTCGGGCGA
TAGAAATGCTCGATCTCAATAGCATTATCGAACGTTACGATGTTCGTCCTGACTGGCGAAGCTCGTTAGACATGGAGCAA
AAGTTTGCTGCAAAAACACAAACGCTATTTGCGGCGATGTTATTGCTCGCGTTTGCACTCTCATATTATCTGCATCGTTT
ATCGAATACAGATAATTTAACTGGGTTAGGCAATCGCCGCCAACTACAGAGAAAATATGGTAATGGCATCGCGGGCGACC
TTGCGATTTTGTATATCGACGTTAACAATTTTAAACCGATTAACGACACATATGGTCATCACTGTGGCGACATGGTGCTC
AAAGCCATCGCCCAAGAAATCAAAAGCCATTGGCGTGGCAAAGGTTTCCGCGTGGGCGGCGATGAGTTTATTTTAATTGG
CAAAGCGTCTCAGCAAGAAGTTGAAGAAGCGTTTGATCGTTTTAGCCGAATTCGACTTGAACAGCATATTGCCGGAAAAC
CCTTGATCATCAGTTCTTCGATTGGCTTGTCCGCGAGGAGGGAGCGGGCCATGAGCTTGCAAAAAGCGCTGCATCTGGCT
GATGTCGACATGTATCAGAGCAAGAATGAACAGCGTGAGATGGGGTATTCTTAA

Upstream 100 bases:

>100_bases
TGCATATCAATAAAAATATTTATGCACGTGACAATGAGTTGATATAAGGTTTCTGCTTCATATTTTGACGCTTGTGTGAA
ACCTAGATTAAGTCAGTGAC

Downstream 100 bases:

>100_bases
CCTCCCTCACTTGAAAAGTGGTGTTTTGCACAAGAGTTAAGCAGTCGCTCGCCTCATCATGGATTATTGCCGAATTGGGG
TTGCAATCTTGAGGGGGATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MIKKFGWLLSCVFVWVSFNCWAKSKEITVATEADDVVTRVLFDAIAEQFTLDVTYVNMPSFDAILDSVARGETDFAANIT
FTHEREKRFSYSHPTNIEYTYLYSNTTNSLRDATRIGVPQDTIYGELIAVNHPDIQLVSYQGHEEAYALISLGQVDGIVD
AINQLKPMLLKGTNAHLLNDEISIKPVSIVSQKGQHLEELTQFAQFIHSEQMQKRLREEITQYQFAIRKQALQQAIAQAP
LDLDEPLTIKLEPIYPYVIYHPDGHVSGITAEVLQQSCDILALNCQLVSRSDERWGEMLQGFIQQEFDLLAPLAMTKARE
QFTYYTSPHYAPQSVIVKRLGYKPNVYSHVSQLIAERVGVVEDDYFDALLTQMLPLKELSRFSDHDAMVRALLANRVDYI
TMDTATLNYLLRNELKLAIEQDDAIGVFDASKISIGLANTEKGRVLAPYFSRAIEMLDLNSIIERYDVRPDWRSSLDMEQ
KFAAKTQTLFAAMLLLAFALSYYLHRLSNTDNLTGLGNRRQLQRKYGNGIAGDLAILYIDVNNFKPINDTYGHHCGDMVL
KAIAQEIKSHWRGKGFRVGGDEFILIGKASQQEVEEAFDRFSRIRLEQHIAGKPLIISSSIGLSARRERAMSLQKALHLA
DVDMYQSKNEQREMGYS

Sequences:

>Translated_657_residues
MIKKFGWLLSCVFVWVSFNCWAKSKEITVATEADDVVTRVLFDAIAEQFTLDVTYVNMPSFDAILDSVARGETDFAANIT
FTHEREKRFSYSHPTNIEYTYLYSNTTNSLRDATRIGVPQDTIYGELIAVNHPDIQLVSYQGHEEAYALISLGQVDGIVD
AINQLKPMLLKGTNAHLLNDEISIKPVSIVSQKGQHLEELTQFAQFIHSEQMQKRLREEITQYQFAIRKQALQQAIAQAP
LDLDEPLTIKLEPIYPYVIYHPDGHVSGITAEVLQQSCDILALNCQLVSRSDERWGEMLQGFIQQEFDLLAPLAMTKARE
QFTYYTSPHYAPQSVIVKRLGYKPNVYSHVSQLIAERVGVVEDDYFDALLTQMLPLKELSRFSDHDAMVRALLANRVDYI
TMDTATLNYLLRNELKLAIEQDDAIGVFDASKISIGLANTEKGRVLAPYFSRAIEMLDLNSIIERYDVRPDWRSSLDMEQ
KFAAKTQTLFAAMLLLAFALSYYLHRLSNTDNLTGLGNRRQLQRKYGNGIAGDLAILYIDVNNFKPINDTYGHHCGDMVL
KAIAQEIKSHWRGKGFRVGGDEFILIGKASQQEVEEAFDRFSRIRLEQHIAGKPLIISSSIGLSARRERAMSLQKALHLA
DVDMYQSKNEQREMGYS
>Mature_657_residues
MIKKFGWLLSCVFVWVSFNCWAKSKEITVATEADDVVTRVLFDAIAEQFTLDVTYVNMPSFDAILDSVARGETDFAANIT
FTHEREKRFSYSHPTNIEYTYLYSNTTNSLRDATRIGVPQDTIYGELIAVNHPDIQLVSYQGHEEAYALISLGQVDGIVD
AINQLKPMLLKGTNAHLLNDEISIKPVSIVSQKGQHLEELTQFAQFIHSEQMQKRLREEITQYQFAIRKQALQQAIAQAP
LDLDEPLTIKLEPIYPYVIYHPDGHVSGITAEVLQQSCDILALNCQLVSRSDERWGEMLQGFIQQEFDLLAPLAMTKARE
QFTYYTSPHYAPQSVIVKRLGYKPNVYSHVSQLIAERVGVVEDDYFDALLTQMLPLKELSRFSDHDAMVRALLANRVDYI
TMDTATLNYLLRNELKLAIEQDDAIGVFDASKISIGLANTEKGRVLAPYFSRAIEMLDLNSIIERYDVRPDWRSSLDMEQ
KFAAKTQTLFAAMLLLAFALSYYLHRLSNTDNLTGLGNRRQLQRKYGNGIAGDLAILYIDVNNFKPINDTYGHHCGDMVL
KAIAQEIKSHWRGKGFRVGGDEFILIGKASQQEVEEAFDRFSRIRLEQHIAGKPLIISSSIGLSARRERAMSLQKALHLA
DVDMYQSKNEQREMGYS

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=157, Percent_Identity=31.8471337579618, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788956, Length=205, Percent_Identity=32.1951219512195, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693134, Length=243, Percent_Identity=29.2181069958848, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081881, Length=159, Percent_Identity=35.2201257861635, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081977, Length=160, Percent_Identity=29.375, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=33.7423312883436, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081974, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1786584, Length=162, Percent_Identity=28.3950617283951, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 74630; Mature: 74630

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKFGWLLSCVFVWVSFNCWAKSKEITVATEADDVVTRVLFDAIAEQFTLDVTYVNMPS
CCCHHHHHHHHHHHHHHHCCEECCCEEEEEECHHHHHHHHHHHHHHHHHEEEEEEECCCC
FDAILDSVARGETDFAANITFTHEREKRFSYSHPTNIEYTYLYSNTTNSLRDATRIGVPQ
HHHHHHHHHCCCCCEEEEEEEEECHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCC
DTIYGELIAVNHPDIQLVSYQGHEEAYALISLGQVDGIVDAINQLKPMLLKGTNAHLLND
HHHCCEEEEECCCCEEEEEECCCCHHHHHEEHHHHHHHHHHHHHHCHHHCCCCCCEEECC
EISIKPVSIVSQKGQHLEELTQFAQFIHSEQMQKRLREEITQYQFAIRKQALQQAIAQAP
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDLDEPLTIKLEPIYPYVIYHPDGHVSGITAEVLQQSCDILALNCQLVSRSDERWGEMLQ
CCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHCCCCEEEEEEEEECCCHHHHHHHHH
GFIQQEFDLLAPLAMTKAREQFTYYTSPHYAPQSVIVKRLGYKPNVYSHVSQLIAERVGV
HHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VEDDYFDALLTQMLPLKELSRFSDHDAMVRALLANRVDYITMDTATLNYLLRNELKLAIE
CCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHEEEE
QDDAIGVFDASKISIGLANTEKGRVLAPYFSRAIEMLDLNSIIERYDVRPDWRSSLDMEQ
CCCCEEEEECCEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
KFAAKTQTLFAAMLLLAFALSYYLHRLSNTDNLTGLGNRRQLQRKYGNGIAGDLAILYID
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
VNNFKPINDTYGHHCGDMVLKAIAQEIKSHWRGKGFRVGGDEFILIGKASQQEVEEAFDR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHHHH
FSRIRLEQHIAGKPLIISSSIGLSARRERAMSLQKALHLADVDMYQSKNEQREMGYS
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MIKKFGWLLSCVFVWVSFNCWAKSKEITVATEADDVVTRVLFDAIAEQFTLDVTYVNMPS
CCCHHHHHHHHHHHHHHHCCEECCCEEEEEECHHHHHHHHHHHHHHHHHEEEEEEECCCC
FDAILDSVARGETDFAANITFTHEREKRFSYSHPTNIEYTYLYSNTTNSLRDATRIGVPQ
HHHHHHHHHCCCCCEEEEEEEEECHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCC
DTIYGELIAVNHPDIQLVSYQGHEEAYALISLGQVDGIVDAINQLKPMLLKGTNAHLLND
HHHCCEEEEECCCCEEEEEECCCCHHHHHEEHHHHHHHHHHHHHHCHHHCCCCCCEEECC
EISIKPVSIVSQKGQHLEELTQFAQFIHSEQMQKRLREEITQYQFAIRKQALQQAIAQAP
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDLDEPLTIKLEPIYPYVIYHPDGHVSGITAEVLQQSCDILALNCQLVSRSDERWGEMLQ
CCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHCCCCEEEEEEEEECCCHHHHHHHHH
GFIQQEFDLLAPLAMTKAREQFTYYTSPHYAPQSVIVKRLGYKPNVYSHVSQLIAERVGV
HHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VEDDYFDALLTQMLPLKELSRFSDHDAMVRALLANRVDYITMDTATLNYLLRNELKLAIE
CCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHEEEE
QDDAIGVFDASKISIGLANTEKGRVLAPYFSRAIEMLDLNSIIERYDVRPDWRSSLDMEQ
CCCCEEEEECCEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
KFAAKTQTLFAAMLLLAFALSYYLHRLSNTDNLTGLGNRRQLQRKYGNGIAGDLAILYID
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
VNNFKPINDTYGHHCGDMVLKAIAQEIKSHWRGKGFRVGGDEFILIGKASQQEVEEAFDR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCHHHHHHHHHH
FSRIRLEQHIAGKPLIISSSIGLSARRERAMSLQKALHLADVDMYQSKNEQREMGYS
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]