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The map label for this gene is hlyB [H]

Identifier: 37679272

GI number: 37679272

Start: 1089515

End: 1091149

Strand: Direct

Name: hlyB [H]

Synonym: VV1088

Alternate gene names: 37679272

Gene position: 1089515-1091149 (Clockwise)

Preceding gene: 37679270

Following gene: 37679273

Centisome position: 32.48

GC content: 50.09

Gene sequence:

>1635_bases
ATGTTCAATCGACTCTCAATTAAACAGAAGCTGATGCTGCCGATTGGCTTACTGACATTGGTGATCGTTGCGACGACACT
GAGCAATGTGCTGCAAGCCAATAAACAAGCTGAGCTTAATTCAATGCTCAATACTCAAGTGCAGCCGGTGATGGATAGCT
TAGAAGATGGTTATCGAGACATTTACCAAGTGATCACAGCGGCTCAAGGAATATTACTGGCGCAGTCACAAAGCGAGGTG
GATTATCACATTGGTGAGTTTAAAGATAATGCCTACAACGTCGAACCGAGAGTTGGCAAAGTCCGAGAGCTGTTTAATGC
CGGTTTGTTGCCAGAATCGGAGCGTCAGCAACTGACGAATCTAACGAGTGCCGCAAAAGCGTGGTTAGCGCTTTATGAGC
CGATGTTTGCCCAGCCAAAAAATGCGGCGGGTTACTACCAAGATAACCGTCGCCAGTTTGAGCAGCAATTTGCCGTATTG
CGCCAGCAACTGGTTTCCATTCGTAGCTTAATCGAGCAAGTGCAAGGGCAGTTAAGAGAAGAGGTTGAACGTTCGATTGA
TTACAGTGTGTATGTGATTGAAGCTGGGGCGGTTATCTCCATCGCATTGGTGCTGCTCTCTTTCGTCATGGCCAAGCAAT
TAATTCTTAAACCCATAGAAGGCATTAGTCACGCCATGGCGGAAATCGCGTCAGGGGATGGCGATCTCTCAAAACGCATG
GTGGCGACCAGTGACGACGAACTCGGACAACTGGCTGGCGCGTTTAATCAATTTGTTTCTCGGATCCACTCCACAGTCGA
GCAGGTGATTATTTCCTCCAACGCGGTGCGCGCTGAAATGGAGAACATCAAAACGCTGACGCAAACGGTGGCCGAGTTCT
CAGGCCAGCAGCAGCAAGAAAGTGAGATGGTGGCCACTGCGGTTAACGAAATGCAGATGACCAGCCAGTCGGTTGCCGAG
AATGCCAATGAAGCGGCGTCGGCCAGTCATAAAGCCAACAGCGAAGCGGACAACACCAACGCCATTTTGAAGACCACCGT
TAGTTCTATTCAAAGTCTCGCCGGGGAAGTCGATAACGCCAGCCAAGTCATTCACAACCTGGATCTCGATGTAGCAAACA
TTGCCTCTATTCTTGATGTGATTCGAGGCATTGCCGATCAAACCAATCTGCTGGCGCTCAATGCAGCGATCGAAGCGGCT
CGCGCGGGGGAACAAGGCCGTGGCTTTGCCGTGGTGGCCGATGAAGTGCGTTCGCTCGCTAGCCGTACTCAAGAAAGCAC
GGGTGAAATTCAATCGATGATCGAAAAACTGCAACAAGGGGCGCGAGAAGCGGTTGCGGTGATGCAAGCGAGTAAAGAGC
GTGGCCACGATACGATTGATAATGCAGGTAAAGCCAGTGATTCGCTGGCAGAAATCATCGGATCGATTTCGTTGATGAGC
CAAATGAACTCACAAATTGCGACCGCCGCCAGCGAGCAAACCAGTGTCAGCGATGAGGTCAACAACAATGTGATGCACAT
TTTGGAAAACAGTCATCACATGGTGGAAATGGTCAGCAGTGCAGATAATGCTTGTCTATCGTTGGCAGGGCAGTGCGAAA
CATTGGACGACTTGGTCGCGCAGTTCAAAGTTTAG

Upstream 100 bases:

>100_bases
TAATTCATACCCCAAGTAAGCCTTGTTCTCAAAACCTCCAGCCAAGGCGCTAGAGTGTCATTGAGAATGGGCGAACAATC
AGCGATGAATAAGGCCATTT

Downstream 100 bases:

>100_bases
AGCCCCTGATTTCTCTCGGTGTTTGTTGAGAGAAGTCTGTGGTAGCGTAGCGAAAAACTCATCAGGAAGAATGCGCTATG
TCTCTTTGGTCGTCGGTGAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MFNRLSIKQKLMLPIGLLTLVIVATTLSNVLQANKQAELNSMLNTQVQPVMDSLEDGYRDIYQVITAAQGILLAQSQSEV
DYHIGEFKDNAYNVEPRVGKVRELFNAGLLPESERQQLTNLTSAAKAWLALYEPMFAQPKNAAGYYQDNRRQFEQQFAVL
RQQLVSIRSLIEQVQGQLREEVERSIDYSVYVIEAGAVISIALVLLSFVMAKQLILKPIEGISHAMAEIASGDGDLSKRM
VATSDDELGQLAGAFNQFVSRIHSTVEQVIISSNAVRAEMENIKTLTQTVAEFSGQQQQESEMVATAVNEMQMTSQSVAE
NANEAASASHKANSEADNTNAILKTTVSSIQSLAGEVDNASQVIHNLDLDVANIASILDVIRGIADQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRSLASRTQESTGEIQSMIEKLQQGAREAVAVMQASKERGHDTIDNAGKASDSLAEIIGSISLMS
QMNSQIATAASEQTSVSDEVNNNVMHILENSHHMVEMVSSADNACLSLAGQCETLDDLVAQFKV

Sequences:

>Translated_544_residues
MFNRLSIKQKLMLPIGLLTLVIVATTLSNVLQANKQAELNSMLNTQVQPVMDSLEDGYRDIYQVITAAQGILLAQSQSEV
DYHIGEFKDNAYNVEPRVGKVRELFNAGLLPESERQQLTNLTSAAKAWLALYEPMFAQPKNAAGYYQDNRRQFEQQFAVL
RQQLVSIRSLIEQVQGQLREEVERSIDYSVYVIEAGAVISIALVLLSFVMAKQLILKPIEGISHAMAEIASGDGDLSKRM
VATSDDELGQLAGAFNQFVSRIHSTVEQVIISSNAVRAEMENIKTLTQTVAEFSGQQQQESEMVATAVNEMQMTSQSVAE
NANEAASASHKANSEADNTNAILKTTVSSIQSLAGEVDNASQVIHNLDLDVANIASILDVIRGIADQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRSLASRTQESTGEIQSMIEKLQQGAREAVAVMQASKERGHDTIDNAGKASDSLAEIIGSISLMS
QMNSQIATAASEQTSVSDEVNNNVMHILENSHHMVEMVSSADNACLSLAGQCETLDDLVAQFKV
>Mature_544_residues
MFNRLSIKQKLMLPIGLLTLVIVATTLSNVLQANKQAELNSMLNTQVQPVMDSLEDGYRDIYQVITAAQGILLAQSQSEV
DYHIGEFKDNAYNVEPRVGKVRELFNAGLLPESERQQLTNLTSAAKAWLALYEPMFAQPKNAAGYYQDNRRQFEQQFAVL
RQQLVSIRSLIEQVQGQLREEVERSIDYSVYVIEAGAVISIALVLLSFVMAKQLILKPIEGISHAMAEIASGDGDLSKRM
VATSDDELGQLAGAFNQFVSRIHSTVEQVIISSNAVRAEMENIKTLTQTVAEFSGQQQQESEMVATAVNEMQMTSQSVAE
NANEAASASHKANSEADNTNAILKTTVSSIQSLAGEVDNASQVIHNLDLDVANIASILDVIRGIADQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRSLASRTQESTGEIQSMIEKLQQGAREAVAVMQASKERGHDTIDNAGKASDSLAEIIGSISLMS
QMNSQIATAASEQTSVSDEVNNNVMHILENSHHMVEMVSSADNACLSLAGQCETLDDLVAQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=366, Percent_Identity=30.327868852459, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=437, Percent_Identity=27.2311212814645, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=32.9861111111111, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=29.7222222222222, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=311, Percent_Identity=30.8681672025724, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58992; Mature: 58992

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNRLSIKQKLMLPIGLLTLVIVATTLSNVLQANKQAELNSMLNTQVQPVMDSLEDGYRD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
IYQVITAAQGILLAQSQSEVDYHIGEFKDNAYNVEPRVGKVRELFNAGLLPESERQQLTN
HHHHHHHHCCHHEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
LTSAAKAWLALYEPMFAQPKNAAGYYQDNRRQFEQQFAVLRQQLVSIRSLIEQVQGQLRE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVERSIDYSVYVIEAGAVISIALVLLSFVMAKQLILKPIEGISHAMAEIASGDGDLSKRM
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VATSDDELGQLAGAFNQFVSRIHSTVEQVIISSNAVRAEMENIKTLTQTVAEFSGQQQQE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
SEMVATAVNEMQMTSQSVAENANEAASASHKANSEADNTNAILKTTVSSIQSLAGEVDNA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
SQVIHNLDLDVANIASILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLA
HHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
SRTQESTGEIQSMIEKLQQGAREAVAVMQASKERGHDTIDNAGKASDSLAEIIGSISLMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
QMNSQIATAASEQTSVSDEVNNNVMHILENSHHMVEMVSSADNACLSLAGQCETLDDLVA
HHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHH
QFKV
HHCC
>Mature Secondary Structure
MFNRLSIKQKLMLPIGLLTLVIVATTLSNVLQANKQAELNSMLNTQVQPVMDSLEDGYRD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
IYQVITAAQGILLAQSQSEVDYHIGEFKDNAYNVEPRVGKVRELFNAGLLPESERQQLTN
HHHHHHHHCCHHEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
LTSAAKAWLALYEPMFAQPKNAAGYYQDNRRQFEQQFAVLRQQLVSIRSLIEQVQGQLRE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVERSIDYSVYVIEAGAVISIALVLLSFVMAKQLILKPIEGISHAMAEIASGDGDLSKRM
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VATSDDELGQLAGAFNQFVSRIHSTVEQVIISSNAVRAEMENIKTLTQTVAEFSGQQQQE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
SEMVATAVNEMQMTSQSVAENANEAASASHKANSEADNTNAILKTTVSSIQSLAGEVDNA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
SQVIHNLDLDVANIASILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLA
HHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
SRTQESTGEIQSMIEKLQQGAREAVAVMQASKERGHDTIDNAGKASDSLAEIIGSISLMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
QMNSQIATAASEQTSVSDEVNNNVMHILENSHHMVEMVSSADNACLSLAGQCETLDDLVA
HHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHH
QFKV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]