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The map label for this gene is znuA [H]

Identifier: 37679222

GI number: 37679222

Start: 1038350

End: 1039225

Strand: Direct

Name: znuA [H]

Synonym: VV1038

Alternate gene names: 37679222

Gene position: 1038350-1039225 (Clockwise)

Preceding gene: 37679219

Following gene: 37679223

Centisome position: 30.95

GC content: 45.21

Gene sequence:

>876_bases
ATGATTCGCTTTTTATTGTGTACTTTTACACTATTTTTGCCGTTACAAGCGCTTGCCGTTGAGGTTTTAACCAGCATTAA
ACCAATACAGCTAATCGTCAATGAGCTTACACAAGAGGTAACGACTCCAACGTTACTCGTGGCTGCCAATGCTTCGCCTC
ACGACTACGCTTTGAAACCTTCTGACGTGAAAAAAGTAAGGCGAGCGGATCTGATAGTGTGGTTTGGCTCATCCTTAGAG
CCTTTTATGACAAAGTTGGTGTCAGAACATTCCAATGTGCTAACGATCAGCGCGATTCCTTCTCTTAAGTTACGTGAATA
CCAAGAGGCTCATCAGCATGATGGCCATGATCACGGTAGCCATGACCCCCATTTTTGGATGGGCATCGACACGGTCAAAC
AAGTTGCTCCAGCGATAACGGCGCGTCTGATCGAAATCGACGCGCAGAACGAAGCACAGTACAAAGCTAACTTAAAGCGT
TTCATGCAGGGATTGGATGAAACGGATACGCGTTTAAATAAGTTGCTACAAGGAGTGAAAGAGCGCGGCTACTATGTGTT
CCATGATGCTTATGGCTACTTTGAACAGCAGTATCAACTTCGCAACCTTGGGCACTTTACGGTTAGCCCGGAGAAAAAGC
CTGGAGCGAAAACGTTGATTGAAATTCGTAACCGTTTAGCAAAAGGCGATGTTGTGTGTGTGTTTGCTGAGCCACAATTT
ACACCAGCGGTTATCGAAAGTGTCATGAGAGGCAGCTCGGCGAAAAAAGGGGTTCTAGACCCTATTGGTACAGAAGTGAC
ACTTGAATCCGGCGGCTACTTTAATTATCTCCTCTCAATGGGGAATGATTTCTACCAATGTTTACATGATAAGTAG

Upstream 100 bases:

>100_bases
GGCTAATTAACGCTGACATGAATAGAACTCATTTGCAATTGGTGAGTGTTATAATGTAACATTTTATCCTAATGAACGCT
ACTTACCAACTTGGATTATT

Downstream 100 bases:

>100_bases
ATCCAACTTCTCCCTATTTACGTGATCCAATTAGTGATATTGGCAACCCTTGCTAAGTTGATATTTTTATCATGCCGCAA
TTTCGCTATGATATTTAGCG

Product: zinc ABC transporter, periplasmic zinc-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIRFLLCTFTLFLPLQALAVEVLTSIKPIQLIVNELTQEVTTPTLLVAANASPHDYALKPSDVKKVRRADLIVWFGSSLE
PFMTKLVSEHSNVLTISAIPSLKLREYQEAHQHDGHDHGSHDPHFWMGIDTVKQVAPAITARLIEIDAQNEAQYKANLKR
FMQGLDETDTRLNKLLQGVKERGYYVFHDAYGYFEQQYQLRNLGHFTVSPEKKPGAKTLIEIRNRLAKGDVVCVFAEPQF
TPAVIESVMRGSSAKKGVLDPIGTEVTLESGGYFNYLLSMGNDFYQCLHDK

Sequences:

>Translated_291_residues
MIRFLLCTFTLFLPLQALAVEVLTSIKPIQLIVNELTQEVTTPTLLVAANASPHDYALKPSDVKKVRRADLIVWFGSSLE
PFMTKLVSEHSNVLTISAIPSLKLREYQEAHQHDGHDHGSHDPHFWMGIDTVKQVAPAITARLIEIDAQNEAQYKANLKR
FMQGLDETDTRLNKLLQGVKERGYYVFHDAYGYFEQQYQLRNLGHFTVSPEKKPGAKTLIEIRNRLAKGDVVCVFAEPQF
TPAVIESVMRGSSAKKGVLDPIGTEVTLESGGYFNYLLSMGNDFYQCLHDK
>Mature_291_residues
MIRFLLCTFTLFLPLQALAVEVLTSIKPIQLIVNELTQEVTTPTLLVAANASPHDYALKPSDVKKVRRADLIVWFGSSLE
PFMTKLVSEHSNVLTISAIPSLKLREYQEAHQHDGHDHGSHDPHFWMGIDTVKQVAPAITARLIEIDAQNEAQYKANLKR
FMQGLDETDTRLNKLLQGVKERGYYVFHDAYGYFEQQYQLRNLGHFTVSPEKKPGAKTLIEIRNRLAKGDVVCVFAEPQF
TPAVIESVMRGSSAKKGVLDPIGTEVTLESGGYFNYLLSMGNDFYQCLHDK

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=286, Percent_Identity=41.2587412587413, Blast_Score=230, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32794; Mature: 32794

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFLLCTFTLFLPLQALAVEVLTSIKPIQLIVNELTQEVTTPTLLVAANASPHDYALKP
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
SDVKKVRRADLIVWFGSSLEPFMTKLVSEHSNVLTISAIPSLKLREYQEAHQHDGHDHGS
HHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
HDPHFWMGIDTVKQVAPAITARLIEIDAQNEAQYKANLKRFMQGLDETDTRLNKLLQGVK
CCCEEEECHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ERGYYVFHDAYGYFEQQYQLRNLGHFTVSPEKKPGAKTLIEIRNRLAKGDVVCVFAEPQF
HCCEEEEECHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCC
TPAVIESVMRGSSAKKGVLDPIGTEVTLESGGYFNYLLSMGNDFYQCLHDK
CHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MIRFLLCTFTLFLPLQALAVEVLTSIKPIQLIVNELTQEVTTPTLLVAANASPHDYALKP
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
SDVKKVRRADLIVWFGSSLEPFMTKLVSEHSNVLTISAIPSLKLREYQEAHQHDGHDHGS
HHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
HDPHFWMGIDTVKQVAPAITARLIEIDAQNEAQYKANLKRFMQGLDETDTRLNKLLQGVK
CCCEEEECHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ERGYYVFHDAYGYFEQQYQLRNLGHFTVSPEKKPGAKTLIEIRNRLAKGDVVCVFAEPQF
HCCEEEEECHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCC
TPAVIESVMRGSSAKKGVLDPIGTEVTLESGGYFNYLLSMGNDFYQCLHDK
CHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]