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The map label for this gene is hlyB [H]

Identifier: 37679188

GI number: 37679188

Start: 999878

End: 1001716

Strand: Direct

Name: hlyB [H]

Synonym: VV1004

Alternate gene names: 37679188

Gene position: 999878-1001716 (Clockwise)

Preceding gene: 37679187

Following gene: 37679190

Centisome position: 29.81

GC content: 49.21

Gene sequence:

>1839_bases
ATGAACAGGATCGCCTTCGATCTTGCGCCAGACACCGAGTTGGCAGCAGAAATGACCGATAGCGTTTATGGACTAAGATT
AACGGTCAAAAACTTTATCGAGACAGGGGATAAACAATTTGTATCTCGTTTCCAAGAGAATGCGTCTCGCTGGACGCAGT
TTATGGATCGCGCCTATAACGAAATACAAAATCCACAACGCGTACAGATCCTTAAAGAGATTGATGGCTTAAAGGCACAG
TATCTCACTACGTTTACTCAAGTGGTGGTGAACAATATGAATATGCGAAATGAGCAGGTTAATGGTGTGCTCAATGTCGA
CGGTCCGCAAATAGAGAAAAGACTCACCAGCGTCATGGAAAGCGCGAAAACCGATGGTGATGTGGTTGCCGCCTATCATG
CCGGACGAGCACTCAGATCGCTCTTGCTCGCGCGGCTTTATGTCGCCAAGTTCTTGGTTGAAAACCAGCAGGCACAAGTA
GAACGATTCAATCAGGAATTTAAAGCGGTACACAGTGAGATTGGCAGCTTACTTGCAACGTTGGAAAATGCGCAACGTCG
CCAATTGACCAACGAAGCAGAATCGCTGTTTACGCAGTATGAAAAAGCGGCCAATGCAGTAACCAGTATGATTTTTGCTC
GCAACGAAGGGATAAAAACGCTGGATACGATCGGGCCGAAAGTCGCGCAACGAATCGCATCGCTTCGTGAGTCGATAGCT
AGCTCAATGGAGCAGGCGGCAGAACAAGCTAATGAGAATGCAGAACAGTCGATCACCTTTCTTTATGGTATCGCGGCGAT
TGCTATTGTCATTGGTTTGTTGTTCTCCTTTGTCATCACGCGCTCGTTAATTGTTAAAGTACAAAGAACGACCAATGTGC
TACAAGATATTGCTCAGGGAGAAGGAGACCTCACCATACGCGTGCCCACCAGTGGCAATGATGAACTCGATGTGTTAGCC
GGGCATTACAACACCTTCGCTGGCAAACTTCAGCACACCATTCGTCAAATGAGCGAAGCGGCCGCACAGATGTTGCAAGC
GGCCGAGATTCTGGCATTAAAAGCGCGAGACACACAAAGTGAGGTGCGAGAGCAGCAATCTCAGGCACAGGTTGCTGCGT
CAGCGATGACGGAAATGTCAGCCAGTGCACAAGAGGTGAGTGCCAGTGCTCAACAGGCGGCGGATCTTTCTCAATCGACG
GCCGATTCTGCGACGCAAGGTTCAAAAGTGGTGATGGAAGCTACACAGTCGATGCAGAAACTTAATGAGCAAATTGCCAG
TGCTGGCGATACAGTCGAACAACTTCGAGCAGACAGTGAGCAAATTGGCACGGTGCTGGATGTTATTCGCAGTATTGCTG
AACAAACCAACTTGCTCGCGCTGAATGCGGCGATTGAAGCGGCAAGGGCAGGGGAGCAGGGAAGAGGATTTGCTGTTGTT
GCTGATGAAGTCCGTTCTCTAGCATCGCGCACTCAAGAGTCGACCGAAGAAATCCAAACCATCATCGGTAGTTTGCAACA
GCGAGCGGAGTTGGCTAACAAGGCGATGCACCAGAGCCGTCAAAGTGCTGAGCAAACCGCAGAGCAGGTGCACTCGGCAG
AATCAGCGTTGACCTCTATCACAGGCTTTATCACCCAGATCAACGATTCCATCGGGCAAATATCCACAGCGGCGAATCAG
CAGGCAATTGCGTCGGATGAGGTCAGTGTCAATGTGAACAATATGTCTGATATCTCGGAGAAGACACTCGTGCAATCGTC
TGAAACCACAGAATCCGCTCAGGCGATGAAGCGATTGGGTGAACAAGTAAACCAGCTACTGAAACAGTTCAAAGTGTAA

Upstream 100 bases:

>100_bases
AATTAGCAAGAAGCTCTATTTTTCACCACTGATTCTGATTCTTATTTTATTGGTGATAGTGCTGGTCAGTGCCAACTTAC
TGAATTAACTGACGAAAGAT

Downstream 100 bases:

>100_bases
ACGACCCCAGTTCATTCAACATAAAAAAGCGCGCCAATTGTCGGCGCGCTTTTATGCTTTTGCACTTTAGACACAAATTA
AGAAACTAAGGCTTGTTGTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQRVQILKEIDGLKAQ
YLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQV
ERFNQEFKAVHSEIGSLLATLENAQRRQLTNEAESLFTQYEKAANAVTSMIFARNEGIKTLDTIGPKVAQRIASLRESIA
SSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTIRVPTSGNDELDVLA
GHYNTFAGKLQHTIRQMSEAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQST
ADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQINDSIGQISTAANQ
QAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV

Sequences:

>Translated_612_residues
MNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQRVQILKEIDGLKAQ
YLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQV
ERFNQEFKAVHSEIGSLLATLENAQRRQLTNEAESLFTQYEKAANAVTSMIFARNEGIKTLDTIGPKVAQRIASLRESIA
SSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTIRVPTSGNDELDVLA
GHYNTFAGKLQHTIRQMSEAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQST
ADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQINDSIGQISTAANQ
QAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV
>Mature_612_residues
MNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQRVQILKEIDGLKAQ
YLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQV
ERFNQEFKAVHSEIGSLLATLENAQRRQLTNEAESLFTQYEKAANAVTSMIFARNEGIKTLDTIGPKVAQRIASLRESIA
SSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTIRVPTSGNDELDVLA
GHYNTFAGKLQHTIRQMSEAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQST
ADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQINDSIGQISTAANQ
QAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=29.3051359516616, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=29.8360655737705, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=26.7326732673267, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788194, Length=366, Percent_Identity=29.7814207650273, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789453, Length=207, Percent_Identity=34.7826086956522, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66782; Mature: 66782

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYN
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EIQNPQRVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVME
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCHHHHHHHHHHHH
SAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQVERFNQEFKAVHSEIGSLLAT
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LENAQRRQLTNEAESLFTQYEKAANAVTSMIFARNEGIKTLDTIGPKVAQRIASLRESIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
SSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGDLTIRVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSEAAAQMLQAAEILALKARDTQS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQSTADSATQGSKVVMEATQSMQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHH
LNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGFITQINDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLG
HHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHH
EQVNQLLKQFKV
HHHHHHHHHHCC
>Mature Secondary Structure
MNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYN
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EIQNPQRVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVME
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCHHHHHHHHHHHH
SAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQVERFNQEFKAVHSEIGSLLAT
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LENAQRRQLTNEAESLFTQYEKAANAVTSMIFARNEGIKTLDTIGPKVAQRIASLRESIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
SSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGDLTIRVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSEAAAQMLQAAEILALKARDTQS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQSTADSATQGSKVVMEATQSMQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHH
LNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVV
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGFITQINDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLG
HHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHH
EQVNQLLKQFKV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]