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The map label for this gene is htpG [H]

Identifier: 37679184

GI number: 37679184

Start: 995544

End: 997454

Strand: Direct

Name: htpG [H]

Synonym: VV1000

Alternate gene names: 37679184

Gene position: 995544-997454 (Clockwise)

Preceding gene: 37679179

Following gene: 37679186

Centisome position: 29.68

GC content: 46.73

Gene sequence:

>1911_bases
GTGAAAATGAACGAGACCGTAGCAAATAATAAAGAAACTCGTGGCTTTCAGTCAGAGGTAAAACAACTTCTCCATCTGAT
GATCCACTCACTGTATTCCAATAAAGAAATCTTCCTACGCGAGTTGATCTCCAACGCGTCTGACGCAGCCGATAAACTGC
GTTTCCAAGCGTTGTCCAATCCTGCACTTTATGAAAATGATGCAGAATTGGGCGTGAAGCTTTCTTTTAACGAAGAACAT
AACACGCTGACGATTTCCGATAACGGGATTGGTATGAGCCGCGAAGAGGTGATTTCGCATCTGGGCACCATTGCCAAATC
TGGTACGGCGGAGTTTTTCTCTAAACTATCTCAAGAGCAATCAAAAGATTCTCAGTTGATTGGTCAGTTTGGTGTTGGTT
TCTATTCGGCCTTCATTGTGGCCGACGCAGTGACGGTACGTACGCGAGCGGCGGGCCTGAATGCAGACCAAGCGGTACTT
TGGCATTCTGCAGGTGAAGGTGAGTACACCGTTGAAGACATTACCAAAGAATCACGTGGTACCGATATTATTCTGCACAT
GCGTGAAGACGGCAAAGAGTTCCTCAACGAATGGCGTTTACGTGATGTGATTGGTAAGTATTCCGATCACATTGGCATTC
CTGTTTCTATTCAAACCCGTGTTCGTGATGAAGAAGGCAAAGAAACAGAAGAAGTGAAGTGGGAGCAAATCAATAAAGCC
CAAGCACTTTGGACGCGCAATAAATCCGATATCTCAGACGAAGAGTATCAAGAGTTTTACAAGCATGTCTCTCACGATTT
TGCTGACCCATTACTTTGGAGTCACAACCGAGTAGAAGGCAAAAACGACTATACCAGCCTCCTTTATATTCCATCGAAAG
CGCCTTGGGATATGATGAACCGTGACCATAAATCTGGTCTTAAACTCTATGTTCAGCGCGTTTTCATCATGGATGATGCT
GAGCAATTTATGCCATCTTACCTGCGTTTTGTCCGCGGTTTGATTGATTCCAACGATCTGCCGCTCAACGTCTCTCGCGA
GATCTTGCAAGACAACAAGGTGACTCAATCGCTACGCGGTGCGTGCACTAAACGTGTTTTAACCATGCTCGAGCGCTTGG
CGAAAAATGACACAGAAAAATACCAAACCTTCTGGAAAGAATTTGGTTTGGTGATGAAGGAAGGCCCCGCTGAAGATTAC
GCCAACCGCGAGAAAGTGGCGGCGTTGTTACGCTTTGCCTCAACAGAAGTGGACTCTGCAGAGCAGACCGTTTCTCTTGA
GTCTTATGTTGAGCGTATGAAAGAAGGCCAAGACAAGATCTACTACCTCACAGCAGACAGCTATGCGGCAGCGAAAAACA
GCCCTCACTTGGAGCAGTTTAAAGCCAAAGGTCTTGAAGTTATTTTAATGTTTGACCGTATTGACGAATGGTTGATGAAC
TACCTAACAGAGTTTGATGGTAAGCAGTTCCAGTCAATCACGAAAGCGGGCCTTGATCTTAGCCAATTTGAAGATGAGCA
AGAGAAAGAGAAGCAGAAAGAAACGGAGCAAGAGTTCCAGTCAGTGGTTGAGCGCACCAAGAGCTACTTGGGTGATCGCG
TGAAAGAGGTGCGTACCACCTTCAAGCTAGCGAATACTCCTGCGGTGGTGGTGACCGACGATTTCGAAATGGGCACGCAG
ATGGCTAAACTACTGGCGGCAGCAGGGCAGGCTGTTCCTGAAGTGAAGTACATTTTTGAGATCAACCCAAATCATACGCT
GGTTAAGCAAATGGCGGATGAGGCGGATGAAGAAGCGTTTGGCCGCTGGGTTGAGGTATTACTCGGCCAAGCGATGTTGG
CGGAACGTGGCTCAATGGAAGATCCTAGCCAGTTCTTAACGGCCATTAACTCGCTTTTGACTAAGGGCTAA

Upstream 100 bases:

>100_bases
AAAAACAGCGTTTTTACCACAATTGACCTTGAATTTACATTTGTCAGCCATATGTTACGTAACAAGCGATTGATTTCCCA
CCCAATTAGAGAACTTTGGA

Downstream 100 bases:

>100_bases
TAAGGCTAAAATCACCAAAAAGCTCGCATTTGCGGGCTTTTTGTATGTATCGGCATTCAACATGCAAAAAAATGATGGTT
TCCAAAGCGATTTGTGAGAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MKMNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEH
NTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLNADQAVL
WHSAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKA
QALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDA
EQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTEKYQTFWKEFGLVMKEGPAEDY
ANREKVAALLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMN
YLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQ
MAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADEADEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG

Sequences:

>Translated_636_residues
MKMNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEH
NTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLNADQAVL
WHSAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKA
QALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDA
EQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTEKYQTFWKEFGLVMKEGPAEDY
ANREKVAALLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMN
YLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQ
MAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADEADEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
>Mature_636_residues
MKMNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEH
NTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLNADQAVL
WHSAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKA
QALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDA
EQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTEKYQTFWKEFGLVMKEGPAEDY
ANREKVAALLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMN
YLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQ
MAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADEADEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI153792590, Length=690, Percent_Identity=37.536231884058, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI20149594, Length=686, Percent_Identity=37.0262390670554, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507677, Length=633, Percent_Identity=36.9668246445498, Blast_Score=406, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=647, Percent_Identity=35.2395672333849, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI154146191, Length=416, Percent_Identity=37.0192307692308, Blast_Score=262, Evalue=7e-70,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=70.8333333333333, Blast_Score=927, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=678, Percent_Identity=37.0206489675516, Blast_Score=449, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=36.2555720653789, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=32.6625386996904, Blast_Score=314, Evalue=8e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=436, Percent_Identity=35.3211009174312, Blast_Score=255, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=681, Percent_Identity=38.1791483113069, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6325016, Length=687, Percent_Identity=37.5545851528384, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=37.956204379562, Blast_Score=464, Evalue=1e-131,
Organism=Drosophila melanogaster, GI21357739, Length=696, Percent_Identity=37.0689655172414, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=651, Percent_Identity=33.4869431643625, Blast_Score=367, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72599; Mature: 72599

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
PALYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQ
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
SKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLNADQAVLWHSAGEGEYTVEDITKESRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHCCC
TDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMN
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEEECCCCCHHHHC
RDHKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ACTKRVLTMLERLAKNDTEKYQTFWKEFGLVMKEGPAEDYANREKVAALLRFASTEVDSA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHCCCCCH
EQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMN
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHH
YLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTT
HHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADEADEEAF
HHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHH
GRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
PALYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQ
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
SKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLNADQAVLWHSAGEGEYTVEDITKESRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHCCC
TDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMN
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEEECCCCCHHHHC
RDHKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ACTKRVLTMLERLAKNDTEKYQTFWKEFGLVMKEGPAEDYANREKVAALLRFASTEVDSA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHCCCCCH
EQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMN
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHH
YLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTT
HHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADEADEEAF
HHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHH
GRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA