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The map label for this gene is yafC [C]

Identifier: 37679026

GI number: 37679026

Start: 845909

End: 846796

Strand: Direct

Name: yafC [C]

Synonym: VV0842

Alternate gene names: 37679026

Gene position: 845909-846796 (Clockwise)

Preceding gene: 37679023

Following gene: 37679027

Centisome position: 25.22

GC content: 50.11

Gene sequence:

>888_bases
GTGATGGCCAATATTCATTGGGAAGGTGTGAACGAGTTTGTTGCGGTGGCCGAAAGCGGCAGCTTCACTCAGGCCGCCAC
GCGCTTAGAAACATCGGTCGCAAATGTGAGCCGCCGAGTCGGACAACTGGAAGAGCGGTTAGGTGTGAAGCTGTTACTGC
GCTCTACAAGAAAAGTGTCACTGACTGAGGCTGGGCAGATCTACGTTCAGCATTGTCGCAGCATACTGGAAGGGCTGCAT
CAAGCGGAGCTAGCCGTGACACAAATGCAGCAGACGCCACAAGGGAAATTAAGAATTACCGCCCCGGTCACTTACGGTGA
GCAAAAGATCGCGCCGTTGCTGAATGGCTTTCTGATTCGTTACCCTAAAATCGATTTAGAGTTAGTGCTCACCAACCAAA
AGCTCGACTTGATTGAGCAGGGTGTGGATATCGCGGTTCGGCTGGGTCAGCTTGAAGATTCTAGTTCCATGGCGCGTCGA
CTAAGTGATCGTCATCTGCATGTTTGTGCGACGCCGGAATATTTTGAACAGCATGGCATGCCTCACACGTTATCGGATTT
GTCGTCACACAACTGCCTGATCGGTACCCACGATCATTGGCGTTTCAAAGAGAATCATCAAGGTCGTTCCATTAAAGTGA
ATGGGCGTATTCGTTGCTCTAGTGGTGTTGTGCTATTGGATGCCGCTCTGAAAGGGATTGGTTTGGTTCAGTTACCGGAT
TACTACGTTGATGAGCACTTGCACGCAGGGCGACTTATCGAAGTGCTGACACATTTTCGTGATGATCGTGAAGGAGTTTG
GGCGCTGTATCCACACAATCGACATTTATCGCCGAAAGTTCGTTTGCTGGTGGATCATCTGGCACAACATTTATCTGCAG
CCGCATAA

Upstream 100 bases:

>100_bases
GAACCAAGAATTTCAGTATAGTCATTCCAAATTGTTTTATAATCCTGTCAAATTGAGAATGACTTTTACACATGAGTAAT
AATGAATGTGAAGGAGAAGT

Downstream 100 bases:

>100_bases
CCGCTATAATCCCCAACCCAGACGATAGAGGTAAACATGGCAGAGACACATCAACCCTTTTCACTTCAAGATGAAGTTTT
TATGCGCAGAGCGATTGAGC

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MMANIHWEGVNEFVAVAESGSFTQAATRLETSVANVSRRVGQLEERLGVKLLLRSTRKVSLTEAGQIYVQHCRSILEGLH
QAELAVTQMQQTPQGKLRITAPVTYGEQKIAPLLNGFLIRYPKIDLELVLTNQKLDLIEQGVDIAVRLGQLEDSSSMARR
LSDRHLHVCATPEYFEQHGMPHTLSDLSSHNCLIGTHDHWRFKENHQGRSIKVNGRIRCSSGVVLLDAALKGIGLVQLPD
YYVDEHLHAGRLIEVLTHFRDDREGVWALYPHNRHLSPKVRLLVDHLAQHLSAAA

Sequences:

>Translated_295_residues
MMANIHWEGVNEFVAVAESGSFTQAATRLETSVANVSRRVGQLEERLGVKLLLRSTRKVSLTEAGQIYVQHCRSILEGLH
QAELAVTQMQQTPQGKLRITAPVTYGEQKIAPLLNGFLIRYPKIDLELVLTNQKLDLIEQGVDIAVRLGQLEDSSSMARR
LSDRHLHVCATPEYFEQHGMPHTLSDLSSHNCLIGTHDHWRFKENHQGRSIKVNGRIRCSSGVVLLDAALKGIGLVQLPD
YYVDEHLHAGRLIEVLTHFRDDREGVWALYPHNRHLSPKVRLLVDHLAQHLSAAA
>Mature_295_residues
MMANIHWEGVNEFVAVAESGSFTQAATRLETSVANVSRRVGQLEERLGVKLLLRSTRKVSLTEAGQIYVQHCRSILEGLH
QAELAVTQMQQTPQGKLRITAPVTYGEQKIAPLLNGFLIRYPKIDLELVLTNQKLDLIEQGVDIAVRLGQLEDSSSMARR
LSDRHLHVCATPEYFEQHGMPHTLSDLSSHNCLIGTHDHWRFKENHQGRSIKVNGRIRCSSGVVLLDAALKGIGLVQLPD
YYVDEHLHAGRLIEVLTHFRDDREGVWALYPHNRHLSPKVRLLVDHLAQHLSAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=36.5853658536585, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1789639, Length=284, Percent_Identity=34.8591549295775, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=31.6725978647687, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081978, Length=285, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=33.7883959044369, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=31.9148936170213, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=32.0284697508897, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI157672245, Length=125, Percent_Identity=40, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788706, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786448, Length=266, Percent_Identity=24.4360902255639, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789173, Length=247, Percent_Identity=27.9352226720648, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790011, Length=255, Percent_Identity=24.3137254901961, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786713, Length=119, Percent_Identity=38.655462184874, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788297, Length=140, Percent_Identity=36.4285714285714, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=25.6055363321799, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787806, Length=116, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=32.6666666666667, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=294, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33150; Mature: 33150

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMANIHWEGVNEFVAVAESGSFTQAATRLETSVANVSRRVGQLEERLGVKLLLRSTRKVS
CCCEEEECCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTEAGQIYVQHCRSILEGLHQAELAVTQMQQTPQGKLRITAPVTYGEQKIAPLLNGFLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCEEE
YPKIDLELVLTNQKLDLIEQGVDIAVRLGQLEDSSSMARRLSDRHLHVCATPEYFEQHGM
CCCCEEEEEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECHHHHHHCCC
PHTLSDLSSHNCLIGTHDHWRFKENHQGRSIKVNGRIRCSSGVVLLDAALKGIGLVQLPD
CCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCEEEEEHHHHCCCEEECCC
YYVDEHLHAGRLIEVLTHFRDDREGVWALYPHNRHLSPKVRLLVDHLAQHLSAAA
HHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMANIHWEGVNEFVAVAESGSFTQAATRLETSVANVSRRVGQLEERLGVKLLLRSTRKVS
CCCEEEECCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTEAGQIYVQHCRSILEGLHQAELAVTQMQQTPQGKLRITAPVTYGEQKIAPLLNGFLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCEEE
YPKIDLELVLTNQKLDLIEQGVDIAVRLGQLEDSSSMARRLSDRHLHVCATPEYFEQHGM
CCCCEEEEEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECHHHHHHCCC
PHTLSDLSSHNCLIGTHDHWRFKENHQGRSIKVNGRIRCSSGVVLLDAALKGIGLVQLPD
CCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCEEEEEHHHHCCCEEECCC
YYVDEHLHAGRLIEVLTHFRDDREGVWALYPHNRHLSPKVRLLVDHLAQHLSAAA
HHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]