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The map label for this gene is yaaJ [H]

Identifier: 37678842

GI number: 37678842

Start: 654097

End: 655572

Strand: Direct

Name: yaaJ [H]

Synonym: VV0658

Alternate gene names: 37678842

Gene position: 654097-655572 (Clockwise)

Preceding gene: 37678840

Following gene: 37678843

Centisome position: 19.5

GC content: 49.53

Gene sequence:

>1476_bases
ATGGCTCGGAAGCACAGACTGGCGCAAACTCAATTTGAGGTAACTATGACAGACTTGATCAATCTAATGAATGACCTGCT
TTGGGGCTCCATTCTTGTTTATTTGCTTGTCGGTGTGGGAATTTATTTCACGGTTCGACTCGGCTTCATTCAGTTCCGCC
ATTTCGGCCACATGTTTTCTGTTCTAAAAAACAGCCGTAAATCGGACAACGCTGGTATCTCCTCCTTTCAAGCGCTTTGT
ACCAGCCTTGCTGCACGTGTAGGTACTGGTAACATGGCCGGTGTGGCTGTTGCGCTGACCGCCGGTGGCCCTGGTGCGAT
TTTCTGGATGTGGCTCATCGCCATGTTGGGTATGGCGACATCATTTGCTGAAAGTACGCTAGCTCAGCTCTACAAAACCA
AAGATGACGATGGCAACTATCGTGGTGGTCCTGCTTACTACATGGAAAAAGGCCTTGGTATGCGTTGGATGGGGGTGCTG
TTCTCCATCTTCCTTATCATTGCTTTTGGTCTGGTGTTTAACGCGGTGCAAGCCAACTCGATTGCCAACGCAATGCAAAA
TGCCTTTGGTTGGGAAAATGCCTACGTAGGCGTTGTGATTGTGGTGCTGTCTGGTGTGATTATCTTTGGTGGTATCAAGC
GTATCGCGCGCACTGCTGAGCTTATCGTTCCAGTGATGGCATTGGCTTACCTTGCTTTAGCGCTGTTTGTGATGTTCTCT
AACTTGGAGAAACTGCCTGACGTACTCATGCTGATCTTCAAGAGCGCTTTTGGCTTGCAAGAAGCGGCTGCGGGTGGTTT
GGGCTACGCGATTGCACAAGCGATGATTAATGGTATCAAACGTGGCCTGTTCTCGAACGAAGCCGGTATGGGTTCCGCGC
CAAACGCTGCGGCGTCAGCAACGCCATATCCTCCACACCCAGCTTCTCAGGGGTACGTGCAAATGCTGGGCGTTTTCATG
GATACTATTGTGATCTGTTCAGCGACCGTTGCAATTATTTTGATGTCGGGCGAGTACGTGCCGCATGGTGAGATTACGGG
CATTGAATTGACTCAGTTAGCGTTAAGCTCGCAAGTGGGGAGCTGGGGGAGCATTTTTGTCGCGGTCGCGATCTTCTTCT
TCGCGTTCACCTCCATCATTGCTAACTACTCTTATGCAGAAACCAACTTGGTCTTCTTGGAGCACAACCACAAAGCTGGC
TTAAATGTTTTCCGTTTGGTCGTGCTTGGTCTTGTGGGCTTTGGTGCGATTGCTCCACTTCCAGTGGTATGGGCTCTGGC
TGACGTATCGATGGGTCTGATGGCCATTGTGAACTTAGTCGCGATCCTGCTGCTATCTGGCATCGTGATCAAACTGGCAA
AAGACTACAACCGTCAGTTACAAGCGGGTAAGTTGCCAACCTTTAATGCCGATGATTTTCCTGAGCTGAAATCTCAACTG
GAAGAAGGCATTTGGGACAACAACAAGAAAGACTAA

Upstream 100 bases:

>100_bases
CGTAAAACGGATGCATGAAGCGACATTTACGATTCTAGATTGCAGAAAGAAAATAATAGTTCACCAAGCTAATTTGACAC
TTGGTTAAGCAATCTGGTGG

Downstream 100 bases:

>100_bases
GGTAGAAATCGAGATTTTCTATCACTGTGATTCGAAAAGCCGTGCAGACAATGCACGGCTTTTTTTGTACCCTAGACAAA
AAGAAAATAAGGGAAAGAAT

Product: sodium/alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MARKHRLAQTQFEVTMTDLINLMNDLLWGSILVYLLVGVGIYFTVRLGFIQFRHFGHMFSVLKNSRKSDNAGISSFQALC
TSLAARVGTGNMAGVAVALTAGGPGAIFWMWLIAMLGMATSFAESTLAQLYKTKDDDGNYRGGPAYYMEKGLGMRWMGVL
FSIFLIIAFGLVFNAVQANSIANAMQNAFGWENAYVGVVIVVLSGVIIFGGIKRIARTAELIVPVMALAYLALALFVMFS
NLEKLPDVLMLIFKSAFGLQEAAAGGLGYAIAQAMINGIKRGLFSNEAGMGSAPNAAASATPYPPHPASQGYVQMLGVFM
DTIVICSATVAIILMSGEYVPHGEITGIELTQLALSSQVGSWGSIFVAVAIFFFAFTSIIANYSYAETNLVFLEHNHKAG
LNVFRLVVLGLVGFGAIAPLPVVWALADVSMGLMAIVNLVAILLLSGIVIKLAKDYNRQLQAGKLPTFNADDFPELKSQL
EEGIWDNNKKD

Sequences:

>Translated_491_residues
MARKHRLAQTQFEVTMTDLINLMNDLLWGSILVYLLVGVGIYFTVRLGFIQFRHFGHMFSVLKNSRKSDNAGISSFQALC
TSLAARVGTGNMAGVAVALTAGGPGAIFWMWLIAMLGMATSFAESTLAQLYKTKDDDGNYRGGPAYYMEKGLGMRWMGVL
FSIFLIIAFGLVFNAVQANSIANAMQNAFGWENAYVGVVIVVLSGVIIFGGIKRIARTAELIVPVMALAYLALALFVMFS
NLEKLPDVLMLIFKSAFGLQEAAAGGLGYAIAQAMINGIKRGLFSNEAGMGSAPNAAASATPYPPHPASQGYVQMLGVFM
DTIVICSATVAIILMSGEYVPHGEITGIELTQLALSSQVGSWGSIFVAVAIFFFAFTSIIANYSYAETNLVFLEHNHKAG
LNVFRLVVLGLVGFGAIAPLPVVWALADVSMGLMAIVNLVAILLLSGIVIKLAKDYNRQLQAGKLPTFNADDFPELKSQL
EEGIWDNNKKD
>Mature_490_residues
ARKHRLAQTQFEVTMTDLINLMNDLLWGSILVYLLVGVGIYFTVRLGFIQFRHFGHMFSVLKNSRKSDNAGISSFQALCT
SLAARVGTGNMAGVAVALTAGGPGAIFWMWLIAMLGMATSFAESTLAQLYKTKDDDGNYRGGPAYYMEKGLGMRWMGVLF
SIFLIIAFGLVFNAVQANSIANAMQNAFGWENAYVGVVIVVLSGVIIFGGIKRIARTAELIVPVMALAYLALALFVMFSN
LEKLPDVLMLIFKSAFGLQEAAAGGLGYAIAQAMINGIKRGLFSNEAGMGSAPNAAASATPYPPHPASQGYVQMLGVFMD
TIVICSATVAIILMSGEYVPHGEITGIELTQLALSSQVGSWGSIFVAVAIFFFAFTSIIANYSYAETNLVFLEHNHKAGL
NVFRLVVLGLVGFGAIAPLPVVWALADVSMGLMAIVNLVAILLLSGIVIKLAKDYNRQLQAGKLPTFNADDFPELKSQLE
EGIWDNNKKD

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=476, Percent_Identity=49.3697478991597, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52828; Mature: 52697

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCC
>Mature Secondary Structure 
ARKHRLAQTQFEVTMTDLINLMNDLLWGSILVYLLVGVGIYFTVRLGFIQFRHFGHMFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKNSRKSDNAGISSFQALCTSLAARVGTGNMAGVAVALTAGGPGAIFWMWLIAMLGMAT
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
SFAESTLAQLYKTKDDDGNYRGGPAYYMEKGLGMRWMGVLFSIFLIIAFGLVFNAVQANS
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANAMQNAFGWENAYVGVVIVVLSGVIIFGGIKRIARTAELIVPVMALAYLALALFVMFS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLEKLPDVLMLIFKSAFGLQEAAAGGLGYAIAQAMINGIKRGLFSNEAGMGSAPNAAASA
HHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TPYPPHPASQGYVQMLGVFMDTIVICSATVAIILMSGEYVPHGEITGIELTQLALSSQVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
SWGSIFVAVAIFFFAFTSIIANYSYAETNLVFLEHNHKAGLNVFRLVVLGLVGFGAIAPL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
PVVWALADVSMGLMAIVNLVAILLLSGIVIKLAKDYNRQLQAGKLPTFNADDFPELKSQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
EEGIWDNNKKD
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]