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The map label for this gene is murG

Identifier: 37678798

GI number: 37678798

Start: 599415

End: 600536

Strand: Direct

Name: murG

Synonym: VV0614

Alternate gene names: 37678798

Gene position: 599415-600536 (Clockwise)

Preceding gene: 37678797

Following gene: 37678799

Centisome position: 17.87

GC content: 50.8

Gene sequence:

>1122_bases
TTGATCATGAATGCCGACTTATCTCGATGGGCAATAAAACAGACTTACAGACAGATGAAAAAGAATAAAAGATTAATGGT
CATGGCAGGAGGCACAGGTGGACACGTTTTTCCTGGCTTGGCGGTGGCGAAAAAATTACAGCAACAAGGCTGGGAAATCC
GCTGGCTCGGGACCGCGGATCGTATGGAAGCCGAGTTGGTGCCAAAGCACGGTATCGATATCGATTTCATTAAAGTCAAA
GGTTTGCGTGGCCAAGGCATCAAACGCCTTGTTTTGGCGCCTTTTCAAATCCTCAATGCTATTTTTCAAGCGAAGGCACA
CATTAAGCGTTGGCAGCCGGATGCCGTGTTAGGGATGGGCGGCTACGTAAGTGGTCCTGGTGGTATTGCCGCTTGGCTAT
CTGGCATTCCTGTGGTCCTGCATGAGCAAAATGCGGTGGCAGGGTTAACCAATCACTGGCTAGCGAAAATCGCCAAAAAG
GTATTTCAAGCCTTCCCGGGGGCATTTAAAGATGCACCAGTCGTAGGTAATCCAGTACGTGAAGATGTCGTTGCCCTTCC
TGATCCCATGCAGAGAATGCAGGACAGAGAAGGTGCAGTACGCATTTTGGTTATGGGTGGCAGCCAAGGTGCCAGAATCC
TCAATCAAACCATGCCACAAGTGATGGCGCAACTCGGGTCTGGTTTTGAGATTCGCCATCAAGCGGGTAAAGGCAGTGCG
GATGAAGTGCGTCTGGCCTACCAACAAGTGGGCGTTGAGCACGTTGAGGTGAGCGAGTTCATTGATGACGTTGCTGCGCA
ATACGCTTGGGCCGACCTATTGGTGTGTCGCTCTGGAGCTCTGACCGTATCGGAAGTCTCTGCCGCTGGCGTAGGGGCCA
TTTTTATCCCATTTATGCACAAAGATCGTCAACAAGCGTTGAATGCTGATCATCTCGTGGCGTGCGGAGCCGCACTGATG
ATTGAGCAGCCGCAACTGACGGTGGATAAGCTCGCGGGAGAAATTCAAAAATTAGGTCGAGATACATTGCTCTCAATGGC
GCTTCACGCCCGAGCAGCAGCACAAAATAATGCCGACCAAGTTGTGGCGGATGCAATTGTCGCCCTAACTGAACAGAAAT
AA

Upstream 100 bases:

>100_bases
GCGGGGATGGTCCCTACCAAAGGTCTTACGTTACCGCTGATCAGCTATGGTGGTTCGAGTTTAATTATTATGTCCATCGC
TGTATCGATTCTTCTGAGAA

Downstream 100 bases:

>100_bases
AGAGAACAGGTTAATGACTATTCAACACAAGCAAGATCTTGCACAGATTCGCGCTATGGTCCCAGAGATGCGCCGAGTGA
AATCCATCCACTTCATTGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MIMNADLSRWAIKQTYRQMKKNKRLMVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEAELVPKHGIDIDFIKVK
GLRGQGIKRLVLAPFQILNAIFQAKAHIKRWQPDAVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNHWLAKIAKK
VFQAFPGAFKDAPVVGNPVREDVVALPDPMQRMQDREGAVRILVMGGSQGARILNQTMPQVMAQLGSGFEIRHQAGKGSA
DEVRLAYQQVGVEHVEVSEFIDDVAAQYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAALM
IEQPQLTVDKLAGEIQKLGRDTLLSMALHARAAAQNNADQVVADAIVALTEQK

Sequences:

>Translated_373_residues
MIMNADLSRWAIKQTYRQMKKNKRLMVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEAELVPKHGIDIDFIKVK
GLRGQGIKRLVLAPFQILNAIFQAKAHIKRWQPDAVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNHWLAKIAKK
VFQAFPGAFKDAPVVGNPVREDVVALPDPMQRMQDREGAVRILVMGGSQGARILNQTMPQVMAQLGSGFEIRHQAGKGSA
DEVRLAYQQVGVEHVEVSEFIDDVAAQYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAALM
IEQPQLTVDKLAGEIQKLGRDTLLSMALHARAAAQNNADQVVADAIVALTEQK
>Mature_373_residues
MIMNADLSRWAIKQTYRQMKKNKRLMVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTADRMEAELVPKHGIDIDFIKVK
GLRGQGIKRLVLAPFQILNAIFQAKAHIKRWQPDAVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNHWLAKIAKK
VFQAFPGAFKDAPVVGNPVREDVVALPDPMQRMQDREGAVRILVMGGSQGARILNQTMPQVMAQLGSGFEIRHQAGKGSA
DEVRLAYQQVGVEHVEVSEFIDDVAAQYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVACGAALM
IEQPQLTVDKLAGEIQKLGRDTLLSMALHARAAAQNNADQVVADAIVALTEQK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=346, Percent_Identity=66.4739884393064, Blast_Score=463, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 40379; Mature: 40379

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMNADLSRWAIKQTYRQMKKNKRLMVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTAD
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHH
RMEAELVPKHGIDIDFIKVKGLRGQGIKRLVLAPFQILNAIFQAKAHIKRWQPDAVLGMG
HHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNHWLAKIAKKVFQAFPGAFKDAPVVGNPVR
CCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EDVVALPDPMQRMQDREGAVRILVMGGSQGARILNQTMPQVMAQLGSGFEIRHQAGKGSA
HHHCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
DEVRLAYQQVGVEHVEVSEFIDDVAAQYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHC
KDRQQALNADHLVACGAALMIEQPQLTVDKLAGEIQKLGRDTLLSMALHARAAAQNNADQ
CCHHHHCCCCHHHHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVADAIVALTEQK
HHHHHHHHHHCCC
>Mature Secondary Structure
MIMNADLSRWAIKQTYRQMKKNKRLMVMAGGTGGHVFPGLAVAKKLQQQGWEIRWLGTAD
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHH
RMEAELVPKHGIDIDFIKVKGLRGQGIKRLVLAPFQILNAIFQAKAHIKRWQPDAVLGMG
HHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNHWLAKIAKKVFQAFPGAFKDAPVVGNPVR
CCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EDVVALPDPMQRMQDREGAVRILVMGGSQGARILNQTMPQVMAQLGSGFEIRHQAGKGSA
HHHCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
DEVRLAYQQVGVEHVEVSEFIDDVAAQYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHC
KDRQQALNADHLVACGAALMIEQPQLTVDKLAGEIQKLGRDTLLSMALHARAAAQNNADQ
CCHHHHCCCCHHHHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVADAIVALTEQK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA