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The map label for this gene is ftsW [H]

Identifier: 37678797

GI number: 37678797

Start: 598283

End: 599482

Strand: Direct

Name: ftsW [H]

Synonym: VV0613

Alternate gene names: 37678797

Gene position: 598283-599482 (Clockwise)

Preceding gene: 37678796

Following gene: 37678798

Centisome position: 17.84

GC content: 46.5

Gene sequence:

>1200_bases
TTGGTGATGGTAGGTAATATCAAAAACAATTTGTTCGGCTGGTTTCGCCACTCACCACCAGACGCCTTGTTTGATCGGCA
GTTGGTTTGGATTGCATTGTGTTTAATGCTGACGGGGCTGGTGATGGTGACATCGGCGTCCTTTCCTATCAGCTCTCGTC
TGACGGATCAGCCTTTTCACTTTATGTTCCGCCATGCCACTTTTTTGTGCTTGGCGTTGGGCACCTCCGCAGTAGTGTTG
CAAATCCCACTACAGAAATGGCAAAGCCATAGCCACTATTTGTTGGGCATCGCATTTGCGTTGCTGGTCGTGGTTTTAAT
TGCGGGTAAATCGGTGAATGGCGCGTCACGCTGGATCCCTCTAGGGCTTTTTAACCTACAGCCAGCGGAAGTGGCCAAGC
TTGCACTGTTTATCTTCATGTCCGGTTATTTGGTTCGTAAACAGGATGAAGTAAGAGCGACCTTTTTTGGTGGCTTCATG
AAACCCATTATGGTTTTTGGCGCGTTAGCGCTATTGCTACTTGGGCAACCCGACTTGGGGACGGTCGTTGTTATGCTGGT
CACCTTGTTTGGCATGCTTTTTATCGCTGGAGCCAAATTGAGCCAGTTTTTGGCGTTGATGGTCGCTGGGATTACCGCGG
TTGTAGGATTGATTCTCATCGAACCGTATCGTGTAAGACGTGTGACGTCTTTCTTAGATCCTTGGGAAGACCCATTTGGT
AGCGGCTATCAGTTGACTCAATCATTAATGGCGTTTGGTCGCGGTGAATGGTTTGGCCAAGGTTTGGGTAACTCGATTCA
AAAATTAGAGTATTTGCCGGAAGCTCACACCGACTTCGTGTTTGCCGTTATGGCAGAAGAGCTTGGTTTCATTGGTGTGG
TGCTGATCTTAGCACTCATTTTTAGCCTAGTGATCAAAGCGGTGTTTATCGGTAAAAAGGCGTTTGAACATCAATTGCAA
TTTGGTGGATATCTCGCTTTTGGTATTGGTATCTGGTTCGCTTTTCAAACCCTAGTTAATGTAGGGGCAGCAGCGGGGAT
GGTCCCTACCAAAGGTCTTACGTTACCGCTGATCAGCTATGGTGGTTCGAGTTTAATTATTATGTCCATCGCTGTATCGA
TTCTTCTGAGAATTGATCATGAATGCCGACTTATCTCGATGGGCAATAAAACAGACTTACAGACAGATGAAAAAGAATAA

Upstream 100 bases:

>100_bases
AATTCAGTAATTTTATGGCGCGAGGCGATCGATTCGCCGAATTGGCTCGCCAGTATGCATAGCGCAACCTCTAACGCGTA
TTTTTAACAAGGCACGATGT

Downstream 100 bases:

>100_bases
AAGATTAATGGTCATGGCAGGAGGCACAGGTGGACACGTTTTTCCTGGCTTGGCGGTGGCGAAAAAATTACAGCAACAAG
GCTGGGAAATCCGCTGGCTC

Product: cell division membrane protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MVMVGNIKNNLFGWFRHSPPDALFDRQLVWIALCLMLTGLVMVTSASFPISSRLTDQPFHFMFRHATFLCLALGTSAVVL
QIPLQKWQSHSHYLLGIAFALLVVVLIAGKSVNGASRWIPLGLFNLQPAEVAKLALFIFMSGYLVRKQDEVRATFFGGFM
KPIMVFGALALLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFLALMVAGITAVVGLILIEPYRVRRVTSFLDPWEDPFG
SGYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVMAEELGFIGVVLILALIFSLVIKAVFIGKKAFEHQLQ
FGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSIAVSILLRIDHECRLISMGNKTDLQTDEKE

Sequences:

>Translated_399_residues
MVMVGNIKNNLFGWFRHSPPDALFDRQLVWIALCLMLTGLVMVTSASFPISSRLTDQPFHFMFRHATFLCLALGTSAVVL
QIPLQKWQSHSHYLLGIAFALLVVVLIAGKSVNGASRWIPLGLFNLQPAEVAKLALFIFMSGYLVRKQDEVRATFFGGFM
KPIMVFGALALLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFLALMVAGITAVVGLILIEPYRVRRVTSFLDPWEDPFG
SGYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVMAEELGFIGVVLILALIFSLVIKAVFIGKKAFEHQLQ
FGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSIAVSILLRIDHECRLISMGNKTDLQTDEKE
>Mature_399_residues
MVMVGNIKNNLFGWFRHSPPDALFDRQLVWIALCLMLTGLVMVTSASFPISSRLTDQPFHFMFRHATFLCLALGTSAVVL
QIPLQKWQSHSHYLLGIAFALLVVVLIAGKSVNGASRWIPLGLFNLQPAEVAKLALFIFMSGYLVRKQDEVRATFFGGFM
KPIMVFGALALLLLGQPDLGTVVVMLVTLFGMLFIAGAKLSQFLALMVAGITAVVGLILIEPYRVRRVTSFLDPWEDPFG
SGYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVMAEELGFIGVVLILALIFSLVIKAVFIGKKAFEHQLQ
FGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSIAVSILLRIDHECRLISMGNKTDLQTDEKE

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=383, Percent_Identity=60.0522193211488, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1786853, Length=335, Percent_Identity=33.7313432835821, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43779; Mature: 43779

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMVGNIKNNLFGWFRHSPPDALFDRQLVWIALCLMLTGLVMVTSASFPISSRLTDQPFH
CEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
FMFRHATFLCLALGTSAVVLQIPLQKWQSHSHYLLGIAFALLVVVLIAGKSVNGASRWIP
HHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LGLFNLQPAEVAKLALFIFMSGYLVRKQDEVRATFFGGFMKPIMVFGALALLLLGQPDLG
EEECCCCHHHHHHHHHHHHHHCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TVVVMLVTLFGMLFIAGAKLSQFLALMVAGITAVVGLILIEPYRVRRVTSFLDPWEDPFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
SGYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVMAEELGFIGVVLILALI
CCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSLVIKAVFIGKKAFEHQLQFGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISY
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHC
GGSSLIIMSIAVSILLRIDHECRLISMGNKTDLQTDEKE
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVMVGNIKNNLFGWFRHSPPDALFDRQLVWIALCLMLTGLVMVTSASFPISSRLTDQPFH
CEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
FMFRHATFLCLALGTSAVVLQIPLQKWQSHSHYLLGIAFALLVVVLIAGKSVNGASRWIP
HHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LGLFNLQPAEVAKLALFIFMSGYLVRKQDEVRATFFGGFMKPIMVFGALALLLLGQPDLG
EEECCCCHHHHHHHHHHHHHHCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TVVVMLVTLFGMLFIAGAKLSQFLALMVAGITAVVGLILIEPYRVRRVTSFLDPWEDPFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
SGYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVMAEELGFIGVVLILALI
CCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSLVIKAVFIGKKAFEHQLQFGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISY
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHC
GGSSLIIMSIAVSILLRIDHECRLISMGNKTDLQTDEKE
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]