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The map label for this gene is mraY

Identifier: 37678795

GI number: 37678795

Start: 595800

End: 596882

Strand: Direct

Name: mraY

Synonym: VV0611

Alternate gene names: 37678795

Gene position: 595800-596882 (Clockwise)

Preceding gene: 37678794

Following gene: 37678796

Centisome position: 17.76

GC content: 49.95

Gene sequence:

>1083_bases
ATGATTATTTGGCTTGCCGAGCTGCTACAGCCATACTTTTCCTTTTTCCGACTGTTTGAATACCTGTCGTTTCGCGCGAT
CTTAAGTGTGCTAACCGCGTTGGGGCTATCGCTTTGGATGGGGCCACGCCTCATTAAGCGCTTACAGTTGCTGCAAATTG
GTCAAGTGGTGCGTAACGAAGGCCCGGAGTCTCATTTTAGTAAACGTGGCACGCCAACCATGGGTGGCGTCATGATCCTC
GCGGCTATTTCCATTACCATTTTGCTGTGGGCCAACTTATCCAACCCTTACGTTTGGGCAGTACTGGCCGTCTTGATGGG
CTATGGTGCGGTCGGGTTTGTTGATGATTATCGCAAAGTGGTGCGCAAGAATACCGATGGTTTGATCGCACGTTGGAAGT
ACTTTTGGCAGTCAGCCATTGCACTGGTAGTGGCTTTCGCTCTATACGCATACGGAAAAGACACTGCAGCGACGCAGTTG
GTTGTGCCTTTCTTTAAAGACGTTATGCCACAACTTGGTCTGATGTACATCGTACTGACCTATTTTGTGATTGTCGGCAC
CAGTAATGCGGTGAACCTAACCGATGGTCTAGATGGTTTGGCGATCATGCCTACGGTTTTGGTGGCTGCAGGGTTTGCCG
TGATTGCTTGGGCAACCGGCAACGTCAATTTTTCTCAGTATCTTCACATCCCGTATCTACCTCACGCCTCTGAACTGGTG
GTGGTATGTACTGCCATCGTCGGTGCTGGTTTGGGCTTCTTATGGTTTAACACTTACCCAGCACAAGTCTTTATGGGCGA
TGTCGGTTCTCTCGCGCTGGGTGGCGCATTGGGGACGATTGCCGTACTTGTACGCCAAGAGTTGGTTTTGGTCATCATGG
GTGGCGTCTTTGTCATGGAAACCTTGTCAGTGATTTTGCAGGTCGGTTCATACAAGTTGCGCGGCCAACGTATTTTCCGC
ATGGCACCCATTCACCACCACTACGAGTTGAAAGGTTGGCCTGAGCCACGTGTTATTGTGCGTTTCTGGATTATTTCTAT
GGTGTTGGTTCTGATCGGTCTAGCGACACTGAAAGTGCGTTAA

Upstream 100 bases:

>100_bases
ATTTGGCCAACGAAAATGAAGCCTGTCATACCGTGTTGGTCAAAGGCGCAAACTCAGCTGGCATGAGTAAAGTGGCTGCT
GCTTTGAAGGAGAACTATCG

Downstream 100 bases:

>100_bases
TCGACGGACACTCTTTTTACGGTGTAATGAAATATGGATCGTTGGCAAGACATCAAACAGGTTGTGGTGGTAGGGCTCGG
TATTACTGGGCTCTCCGTCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR

Sequences:

>Translated_360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR
>Mature_360_residues
MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNEGPESHFSKRGTPTMGGVMIL
AAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=82.2222222222222, Blast_Score=587, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39837; Mature: 39837

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNE
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQLVVPFFKDVMPQLGLMYIVLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHCCHHHEEEECCCCCHHHEEECCCCCCHHHHH
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIWLAELLQPYFSFFRLFEYLSFRAILSVLTALGLSLWMGPRLIKRLQLLQIGQVVRNE
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAISITILLWANLSNPYVWAVLAVLMGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQLVVPFFKDVMPQLGLMYIVLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAVIAWATGNVNFSQYLHIPYLPHASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHCCHHHEEEECCCCCHHHEEECCCCCCHHHHH
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQELVLVIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLIGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA