| Definition | Vibrio vulnificus YJ016 chromosome I, complete sequence. |
|---|---|
| Accession | NC_005139 |
| Length | 3,354,505 |
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The map label for this gene is ftsI [H]
Identifier: 37678792
GI number: 37678792
Start: 591202
End: 592932
Strand: Direct
Name: ftsI [H]
Synonym: VV0608
Alternate gene names: 37678792
Gene position: 591202-592932 (Clockwise)
Preceding gene: 37678791
Following gene: 37678793
Centisome position: 17.62
GC content: 51.59
Gene sequence:
>1731_bases ATGATGGGTAAAAAGAGCAAAACCACCGTCAAACCCAAAGAGAGTGAGCAAGGGACATCTTTGCTTATCCGCTGGCGTTT CCATTTAGTCCTAGGATTTGTATTCCTCGCGTTTGCCGCGCTTGTTGTTCGTCTTGCATTTATTCAAGTCATTGAGCCTG ACAACCTTATTCGTGAAGGGGATCTGCGTTCTATCCGTGTGAAAGCCCTTCCGTCCGCGCGAGGTATCATCTCCGATCGC AATGGTGAACCTTTAGCGGTGAGTGTTCCCGTTGAAGCTGTCTGGGCCGATCCGGTGACGATTTTCAAAGAAAAGGCGCT GGATAACAAACAGCGTTGGTATGCGTTAGCCGATGTGTTAGGGCTGCAGCGTGAAGAATTGATTGAACGTATCGAGCGCA ATGAAAACCGCCGCTTCATCTACTTGCAGCGCCAAGTGAGCCCCGCGATGGCGAACTACATACGCGAGCTTAAAATTCCA GGCGTGGGGCTGAAATCAGAATCGCGCCGCTATTATCCCGCTGGTGAAGTGAGTGCTCATTTAGTGGGCGTAACGGGTAT CGATGGTCACGGCCTTGAAGGGGTGGAACGCAGTTACGATAACTGGTTGACTGGTGAAGCGGGTAAACAGACGATTCGTA AAGACCGTTATGGCCGCGTGGTGGAAAACATTGCCTATGAAGACAGGCAAGAAGGCAAGTCACTTGAACTCACCATTGAT CAGCGTCTCCAAGCCATTGCTTATCGCGCCATCAAACAGGCGGTGGCCGATCACCGTGCGACTTCTGGTTCGGCAGTGAT GTTGGATGTAAAAACCGGCGCCGTGTTGGCGATGGTCAACGCGCCTTCTTACAACCCAAACAATCGCAGTGATTGGCAAA GCTACAAGATGCGTAACCGCATCATCACCGATTCGTTGGAGCCAGGCTCTACGGTGAAGCCTTTTGTGATTCTTGCCGCG CTGGAAAACGGCGTTGCCACCAAAGACACGGTGATCGACACGGGCAACGGCATTCTCCAAGTCGGTGGCAGTCGAGTTCG AGATACGAGTAAGGTCGGTAAAGCGGATCTGACCGAAATCCTCAAAAAATCCAGTAATATCGGCGTGACAAAACTGTCGA TGGAAATGCCCGTGGAAGCGATTCTCGGCATGTATAACTCGGTTGGGCTTGGAGAGCCTTCTGGGTTAAATCTTGTTGGC GAAGTGACCGGTATTTTCCCTACTCGTTCGCGTTGGTCTCCGATTGAGAGAGCGACGCTGTCGTTTGGGTACGGTCTGTC GATCACTCCGATTCAATTGGCTCATGCCTACGCAACCTTGGGCAATGAAGGTATGTACGAGCCGATCCACATCATCAAAA GCAACGATCGTGATATGGCGAAGCAAGTGGTGTCCAAACAACACGCTCGTGAAGTGCTCAATATGCTTGAAACCGTGACG CAAAAAGGCGGCTCAGCCAGACGAGCGGCCGTTCCGGGTTACCGGGTTGGGGCGAAAACGGGGACATCACGTAAAGCAAC GGCTGGTGGGTATAGCGATGAATACATCACCTACACGGCGGGCGTGGCGCCAGTTAGCGATCCGAGAATTGCTTTGGTCG TGGTGGTCAATGAACCACAAGGGGATGATTACTATGGCGGTTCCGTCGCTTCCCCTGTTTTTTCAGAAATTATGAAAGGT GCGCTGCAAATTTTGAATGTGGCACCCGATGAAAATGCATTCCAGAACTAG
Upstream 100 bases:
>100_bases AGACCGCACTGGCTGAGCACAGTCGCGTGCAAGAGATGGCGAAAAAAGAGCTCGAAATGAAACGGCCTGATGGCGACAAA GAAGTGGTGATTAATCTGAA
Downstream 100 bases:
>100_bases TTTTATGGCTGAGCGTGGCTCGGAGAACAAAATGCGAAATACCATGAATCTGACAAATTTATTAGCGCCGTGGCTAGATT GTCCTGAGCTTGCGGACATT
Product: cell division protein FtsI
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 576; Mature: 576
Protein sequence:
>576_residues MMGKKSKTTVKPKESEQGTSLLIRWRFHLVLGFVFLAFAALVVRLAFIQVIEPDNLIREGDLRSIRVKALPSARGIISDR NGEPLAVSVPVEAVWADPVTIFKEKALDNKQRWYALADVLGLQREELIERIERNENRRFIYLQRQVSPAMANYIRELKIP GVGLKSESRRYYPAGEVSAHLVGVTGIDGHGLEGVERSYDNWLTGEAGKQTIRKDRYGRVVENIAYEDRQEGKSLELTID QRLQAIAYRAIKQAVADHRATSGSAVMLDVKTGAVLAMVNAPSYNPNNRSDWQSYKMRNRIITDSLEPGSTVKPFVILAA LENGVATKDTVIDTGNGILQVGGSRVRDTSKVGKADLTEILKKSSNIGVTKLSMEMPVEAILGMYNSVGLGEPSGLNLVG EVTGIFPTRSRWSPIERATLSFGYGLSITPIQLAHAYATLGNEGMYEPIHIIKSNDRDMAKQVVSKQHAREVLNMLETVT QKGGSARRAAVPGYRVGAKTGTSRKATAGGYSDEYITYTAGVAPVSDPRIALVVVVNEPQGDDYYGGSVASPVFSEIMKG ALQILNVAPDENAFQN
Sequences:
>Translated_576_residues MMGKKSKTTVKPKESEQGTSLLIRWRFHLVLGFVFLAFAALVVRLAFIQVIEPDNLIREGDLRSIRVKALPSARGIISDR NGEPLAVSVPVEAVWADPVTIFKEKALDNKQRWYALADVLGLQREELIERIERNENRRFIYLQRQVSPAMANYIRELKIP GVGLKSESRRYYPAGEVSAHLVGVTGIDGHGLEGVERSYDNWLTGEAGKQTIRKDRYGRVVENIAYEDRQEGKSLELTID QRLQAIAYRAIKQAVADHRATSGSAVMLDVKTGAVLAMVNAPSYNPNNRSDWQSYKMRNRIITDSLEPGSTVKPFVILAA LENGVATKDTVIDTGNGILQVGGSRVRDTSKVGKADLTEILKKSSNIGVTKLSMEMPVEAILGMYNSVGLGEPSGLNLVG EVTGIFPTRSRWSPIERATLSFGYGLSITPIQLAHAYATLGNEGMYEPIHIIKSNDRDMAKQVVSKQHAREVLNMLETVT QKGGSARRAAVPGYRVGAKTGTSRKATAGGYSDEYITYTAGVAPVSDPRIALVVVVNEPQGDDYYGGSVASPVFSEIMKG ALQILNVAPDENAFQN >Mature_576_residues MMGKKSKTTVKPKESEQGTSLLIRWRFHLVLGFVFLAFAALVVRLAFIQVIEPDNLIREGDLRSIRVKALPSARGIISDR NGEPLAVSVPVEAVWADPVTIFKEKALDNKQRWYALADVLGLQREELIERIERNENRRFIYLQRQVSPAMANYIRELKIP GVGLKSESRRYYPAGEVSAHLVGVTGIDGHGLEGVERSYDNWLTGEAGKQTIRKDRYGRVVENIAYEDRQEGKSLELTID QRLQAIAYRAIKQAVADHRATSGSAVMLDVKTGAVLAMVNAPSYNPNNRSDWQSYKMRNRIITDSLEPGSTVKPFVILAA LENGVATKDTVIDTGNGILQVGGSRVRDTSKVGKADLTEILKKSSNIGVTKLSMEMPVEAILGMYNSVGLGEPSGLNLVG EVTGIFPTRSRWSPIERATLSFGYGLSITPIQLAHAYATLGNEGMYEPIHIIKSNDRDMAKQVVSKQHAREVLNMLETVT QKGGSARRAAVPGYRVGAKTGTSRKATAGGYSDEYITYTAGVAPVSDPRIALVVVVNEPQGDDYYGGSVASPVFSEIMKG ALQILNVAPDENAFQN
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=568, Percent_Identity=50.3521126760563, Blast_Score=597, Evalue=1e-172, Organism=Escherichia coli, GI1786854, Length=622, Percent_Identity=26.8488745980707, Blast_Score=158, Evalue=1e-39,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 63108; Mature: 63108
Theoretical pI: Translated: 9.61; Mature: 9.61
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMGKKSKTTVKPKESEQGTSLLIRWRFHLVLGFVFLAFAALVVRLAFIQVIEPDNLIREG CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC DLRSIRVKALPSARGIISDRNGEPLAVSVPVEAVWADPVTIFKEKALDNKQRWYALADVL CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHCCCHHHHHHHHHHH GLQREELIERIERNENRRFIYLQRQVSPAMANYIRELKIPGVGLKSESRRYYPAGEVSAH CCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE LVGVTGIDGHGLEGVERSYDNWLTGEAGKQTIRKDRYGRVVENIAYEDRQEGKSLELTID EEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH QRLQAIAYRAIKQAVADHRATSGSAVMLDVKTGAVLAMVNAPSYNPNNRSDWQSYKMRNR HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHH IITDSLEPGSTVKPFVILAALENGVATKDTVIDTGNGILQVGGSRVRDTSKVGKADLTEI HCCCCCCCCCCCCCEEEEEEHHCCCCCCCCEEECCCCEEEECCCHHCCHHHCCHHHHHHH LKKSSNIGVTKLSMEMPVEAILGMYNSVGLGEPSGLNLVGEVTGIFPTRSRWSPIERATL HHCCCCCCEEEEEHHCCHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCCCCCCCHHHHHH SFGYGLSITPIQLAHAYATLGNEGMYEPIHIIKSNDRDMAKQVVSKQHAREVLNMLETVT EECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH QKGGSARRAAVPGYRVGAKTGTSRKATAGGYSDEYITYTAGVAPVSDPRIALVVVVNEPQ HCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC GDDYYGGSVASPVFSEIMKGALQILNVAPDENAFQN CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC >Mature Secondary Structure MMGKKSKTTVKPKESEQGTSLLIRWRFHLVLGFVFLAFAALVVRLAFIQVIEPDNLIREG CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC DLRSIRVKALPSARGIISDRNGEPLAVSVPVEAVWADPVTIFKEKALDNKQRWYALADVL CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHCCCHHHHHHHHHHH GLQREELIERIERNENRRFIYLQRQVSPAMANYIRELKIPGVGLKSESRRYYPAGEVSAH CCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE LVGVTGIDGHGLEGVERSYDNWLTGEAGKQTIRKDRYGRVVENIAYEDRQEGKSLELTID EEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH QRLQAIAYRAIKQAVADHRATSGSAVMLDVKTGAVLAMVNAPSYNPNNRSDWQSYKMRNR HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHH IITDSLEPGSTVKPFVILAALENGVATKDTVIDTGNGILQVGGSRVRDTSKVGKADLTEI HCCCCCCCCCCCCCEEEEEEHHCCCCCCCCEEECCCCEEEECCCHHCCHHHCCHHHHHHH LKKSSNIGVTKLSMEMPVEAILGMYNSVGLGEPSGLNLVGEVTGIFPTRSRWSPIERATL HHCCCCCCEEEEEHHCCHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCCCCCCCHHHHHH SFGYGLSITPIQLAHAYATLGNEGMYEPIHIIKSNDRDMAKQVVSKQHAREVLNMLETVT EECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH QKGGSARRAAVPGYRVGAKTGTSRKATAGGYSDEYITYTAGVAPVSDPRIALVVVVNEPQ HCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC GDDYYGGSVASPVFSEIMKGALQILNVAPDENAFQN CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]