| Definition | Vibrio vulnificus YJ016 chromosome I, complete sequence. |
|---|---|
| Accession | NC_005139 |
| Length | 3,354,505 |
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The map label for this gene is kduD [H]
Identifier: 37678736
GI number: 37678736
Start: 536292
End: 537053
Strand: Direct
Name: kduD [H]
Synonym: VV0552
Alternate gene names: 37678736
Gene position: 536292-537053 (Clockwise)
Preceding gene: 37678735
Following gene: 37678737
Centisome position: 15.99
GC content: 45.01
Gene sequence:
>762_bases ATGATTCTCAATTCGTTCAATCTTCAAGGTAAAGTGGCTATCGTAACTGGTTGTGATACTGGTTTAGGGCAAGGTATGGC ATTGGGTTTGGCTAACGCAGGCTGTGATATCGTTGGCGTAAATATTGTGGAGCCAACTGAGACCATTGCACTTATTGAGC AAACAGGGCGTAAGTTTGTTGATGTGCGTGCTAACCTCATGAAGCTTGATGACATTCCTGCCATTGTTGACCGCGCAGTG ACAGAGTTTGGTCGCATCGATATTCTTGTAAACAACGCTGGTATCATTCGTCGCAATGACGCGATTGATTTCTCTGAGCA AGATTGGGATGACGTAATGAATATTAACGTTAAGTCAGTGTTCTTCTTGTCTCAAGCGGTAGCAAAACAGTTTATTGCCC AGGGAGAAGGTGGCAAAATCATTAATATTGCTTCAATGTTGTCTTTCCAAGGTGGTATTCGCGTTCCTTCATACACGACA TCTAAAAGCGGCGTAATGGGTGTAACTCGTCTAATGGCAAATGAATGGGCGAAACACAATATCAACGTTAATGCGATTGC TCCTGGCTACATGGCAACCAATAACACTACTGCGCTTCGTGCTGATGAAACCCGCAATAAAGAAATCCTAGACCGTATTC CTGCGGGTCGTTGGGGTGAGCCATCAGATTTAGCTGGCCCTTGTGTCTTCTTGGCATCGAGCGCATCTAACTACATTAAT GGCTACACGATAGCGGTTGATGGCGGCTGGCTATCTCGTTAA
Upstream 100 bases:
>100_bases ATAACTATACACCTTTTCATCTTATTGCTATTTTGGCGGCACAAAGTGAAATGTATGCTGAAGATCTTTCAGCATCTGAT GTAGTTATGAAGGAATAAGC
Downstream 100 bases:
>100_bases TCAAGGTTGAATACCAACAAGACTAGGAGTGATTGGTGGACGTATTCTCTCAGCCATTGTCCATTGCCCAGATCGTAGGG CTACTGAGCTTCGCGTTAGG
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 253; Mature: 253
Protein sequence:
>253_residues MILNSFNLQGKVAIVTGCDTGLGQGMALGLANAGCDIVGVNIVEPTETIALIEQTGRKFVDVRANLMKLDDIPAIVDRAV TEFGRIDILVNNAGIIRRNDAIDFSEQDWDDVMNINVKSVFFLSQAVAKQFIAQGEGGKIINIASMLSFQGGIRVPSYTT SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTTALRADETRNKEILDRIPAGRWGEPSDLAGPCVFLASSASNYIN GYTIAVDGGWLSR
Sequences:
>Translated_253_residues MILNSFNLQGKVAIVTGCDTGLGQGMALGLANAGCDIVGVNIVEPTETIALIEQTGRKFVDVRANLMKLDDIPAIVDRAV TEFGRIDILVNNAGIIRRNDAIDFSEQDWDDVMNINVKSVFFLSQAVAKQFIAQGEGGKIINIASMLSFQGGIRVPSYTT SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTTALRADETRNKEILDRIPAGRWGEPSDLAGPCVFLASSASNYIN GYTIAVDGGWLSR >Mature_253_residues MILNSFNLQGKVAIVTGCDTGLGQGMALGLANAGCDIVGVNIVEPTETIALIEQTGRKFVDVRANLMKLDDIPAIVDRAV TEFGRIDILVNNAGIIRRNDAIDFSEQDWDDVMNINVKSVFFLSQAVAKQFIAQGEGGKIINIASMLSFQGGIRVPSYTT SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTTALRADETRNKEILDRIPAGRWGEPSDLAGPCVFLASSASNYIN GYTIAVDGGWLSR
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=32.6771653543307, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.5301204819277, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=31.7460317460317, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=30.0411522633745, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=28.3464566929134, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=30.8, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=29.3388429752066, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=32.0158102766798, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI4504505, Length=261, Percent_Identity=27.9693486590038, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=27.9527559055118, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=28.2926829268293, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=28.4263959390863, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=214, Percent_Identity=28.9719626168224, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=29.1208791208791, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=29.1457286432161, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI20149619, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.635838150289, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI209862901, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI19923983, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=25.9842519685039, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=80.6324110671937, Blast_Score=432, Evalue=1e-122, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=45.0592885375494, Blast_Score=209, Evalue=1e-55, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=41.5322580645161, Blast_Score=185, Evalue=2e-48, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=35.1020408163265, Blast_Score=149, Evalue=2e-37, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=35.0806451612903, Blast_Score=138, Evalue=3e-34, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.2834645669291, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=34.1269841269841, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=27.5590551181102, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=27.8884462151394, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=27.3469387755102, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=26.1044176706827, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=25.2918287937743, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1788891, Length=218, Percent_Identity=28.4403669724771, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787526, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=35.361216730038, Blast_Score=127, Evalue=7e-30, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=31.8548387096774, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=34.8178137651822, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=34.6613545816733, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=28.5140562248996, Blast_Score=115, Evalue=1e-26, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.1746031746032, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=30.7392996108949, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=30.7392996108949, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=30.8270676691729, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=31.4176245210728, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.4339622641509, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=31.7708333333333, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.5019157088123, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.4182509505703, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=30.0380228136882, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=28.6821705426357, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=31.5384615384615, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=30.4182509505703, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=31.4176245210728, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=29.1338582677165, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=27.6264591439689, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=26.5151515151515, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=29.4573643410853, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=168, Percent_Identity=30.3571428571429, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=28, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508651, Length=158, Percent_Identity=32.9113924050633, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=26.7015706806283, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI32563809, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17507613, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=26.3779527559055, Blast_Score=73, Evalue=5e-14, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.9397590361446, Blast_Score=134, Evalue=6e-32, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.4741035856574, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=29.7619047619048, Blast_Score=118, Evalue=5e-27, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32.4, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=31.1023622047244, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=28.6852589641434, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=27.7551020408163, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=31.496062992126, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=29.6875, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24649181, Length=198, Percent_Identity=29.2929292929293, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=30.3664921465969, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=30.3664921465969, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=29.7979797979798, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24640492, Length=215, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=25.3807106598985, Blast_Score=68, Evalue=7e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 27184; Mature: 27184
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MILNSFNLQGKVAIVTGCDTGLGQGMALGLANAGCDIVGVNIVEPTETIALIEQTGRKFV CEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHCCCEE DVRANLMKLDDIPAIVDRAVTEFGRIDILVNNAGIIRRNDAIDFSEQDWDDVMNINVKSV EHHHHEEECCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCHHHHCCCHHHH FFLSQAVAKQFIAQGEGGKIINIASMLSFQGGIRVPSYTTSKSGVMGVTRLMANEWAKHN HHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC INVNAIAPGYMATNNTTALRADETRNKEILDRIPAGRWGEPSDLAGPCVFLASSASNYIN CCEEEECCCEEECCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC GYTIAVDGGWLSR CEEEEECCCCCCC >Mature Secondary Structure MILNSFNLQGKVAIVTGCDTGLGQGMALGLANAGCDIVGVNIVEPTETIALIEQTGRKFV CEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHCCCEE DVRANLMKLDDIPAIVDRAVTEFGRIDILVNNAGIIRRNDAIDFSEQDWDDVMNINVKSV EHHHHEEECCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCHHHHCCCHHHH FFLSQAVAKQFIAQGEGGKIINIASMLSFQGGIRVPSYTTSKSGVMGVTRLMANEWAKHN HHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC INVNAIAPGYMATNNTTALRADETRNKEILDRIPAGRWGEPSDLAGPCVFLASSASNYIN CCEEEECCCEEECCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC GYTIAVDGGWLSR CEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]