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The map label for this gene is srlR [H]

Identifier: 37678685

GI number: 37678685

Start: 488217

End: 488978

Strand: Direct

Name: srlR [H]

Synonym: VV0501

Alternate gene names: 37678685

Gene position: 488217-488978 (Clockwise)

Preceding gene: 37678682

Following gene: 37678686

Centisome position: 14.55

GC content: 49.08

Gene sequence:

>762_bases
ATGTCGAAACGAAACACTCAGCTGAGAAGACACAGTATTTCTAAACTGGTTAATGAGAAAGGAGAGGTCAGTGTTGACGA
GCTCGCTCATAAATTTGATACCTCAGAAGTCACGATTCGAAAGGATTTGGCGTCATTAGAAAAGAATGGCCAATTGTTGC
GCCGCTACGGTGGCGCGATTGCGATCCCCAAAGAAGTGATTCATGAAGAAATGAGTCAAAATATTTCGGATCGAAAGCTA
AAACTCGCAGAGAAAGCGGCGGAGCTGATTCGAGACCACAACCGTATCGTGATCGACAGCGGTAGCACAACCGGGGCGCT
TATTCAGCAACTCAACAGCAAACGCGGTTTGGTGGTGATGACCAACTCATTGCACGTAGCCAACGCGTTGAACGAGCTGG
AAAGTGAACCTACGCTTTTAATGACTGGCGGAACTTGGGACAACCATTCTGAATCCTTCCAAGGAAAAGTGGCCGAATCG
GTGTTGCGATCGTACGACTTTGATCAGCTCTTCATCGGCGCAGATGGTGTTGACCTGACCCGTGGGACCACCACATTTAA
TGAACTTGTCGGCCTGAGTAAAGTGATGGCGGAAGTCTCACGAGAAGTGATCGTCATGGTTGAGTCCGACAAGGTGGGGC
GCAAAATCCCGAATCTCGAACTGGCGTGGGAGATGATCGATATTCTGATCACCAACAATGACTTGCTGCCAGAACACAAA
GCCGAAATGGAAGCCAATGGCGTGCGCGTCATCTGTGCCTAA

Upstream 100 bases:

>100_bases
TCAGCGCTATTTATTAATTTTTTGGATCGAAATAAATGGACTAAAAAGTTTCACTTCAACTATAATTTCTTTCAATTCGA
AACTTAAAGTTAAAAATTAA

Downstream 100 bases:

>100_bases
TCTTTTTCCTCGTAACGACTTTTGCTTGCGAAGTACGAGGAAGCAAAAAATAAAAATGGAGATAAAACATGTGTGGAATC
GTTGGTGCCGTTGCACAGCG

Product: transcriptional regulator of sugar metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSKRNTQLRRHSISKLVNEKGEVSVDELAHKFDTSEVTIRKDLASLEKNGQLLRRYGGAIAIPKEVIHEEMSQNISDRKL
KLAEKAAELIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDNHSESFQGKVAES
VLRSYDFDQLFIGADGVDLTRGTTTFNELVGLSKVMAEVSREVIVMVESDKVGRKIPNLELAWEMIDILITNNDLLPEHK
AEMEANGVRVICA

Sequences:

>Translated_253_residues
MSKRNTQLRRHSISKLVNEKGEVSVDELAHKFDTSEVTIRKDLASLEKNGQLLRRYGGAIAIPKEVIHEEMSQNISDRKL
KLAEKAAELIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDNHSESFQGKVAES
VLRSYDFDQLFIGADGVDLTRGTTTFNELVGLSKVMAEVSREVIVMVESDKVGRKIPNLELAWEMIDILITNNDLLPEHK
AEMEANGVRVICA
>Mature_252_residues
SKRNTQLRRHSISKLVNEKGEVSVDELAHKFDTSEVTIRKDLASLEKNGQLLRRYGGAIAIPKEVIHEEMSQNISDRKLK
LAEKAAELIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDNHSESFQGKVAESV
LRSYDFDQLFIGADGVDLTRGTTTFNELVGLSKVMAEVSREVIVMVESDKVGRKIPNLELAWEMIDILITNNDLLPEHKA
EMEANGVRVICA

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=247, Percent_Identity=41.7004048582996, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=36.6141732283465, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=32.9059829059829, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788069, Length=249, Percent_Identity=30.1204819277108, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787540, Length=207, Percent_Identity=32.3671497584541, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789829, Length=213, Percent_Identity=29.5774647887324, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=26.8774703557312, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28118; Mature: 27987

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRNTQLRRHSISKLVNEKGEVSVDELAHKFDTSEVTIRKDLASLEKNGQLLRRYGGAI
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCE
AIPKEVIHEEMSQNISDRKLKLAEKAAELIRDHNRIVIDSGSTTGALIQQLNSKRGLVVM
ECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEE
TNSLHVANALNELESEPTLLMTGGTWDNHSESFQGKVAESVLRSYDFDQLFIGADGVDLT
ECCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSKVMAEVSREVIVMVESDKVGRKIPNLELAWEMIDILITNNDLLPEHK
CCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHEECCCCCCCHH
AEMEANGVRVICA
HHHCCCCEEEEEC
>Mature Secondary Structure 
SKRNTQLRRHSISKLVNEKGEVSVDELAHKFDTSEVTIRKDLASLEKNGQLLRRYGGAI
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCE
AIPKEVIHEEMSQNISDRKLKLAEKAAELIRDHNRIVIDSGSTTGALIQQLNSKRGLVVM
ECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEE
TNSLHVANALNELESEPTLLMTGGTWDNHSESFQGKVAESVLRSYDFDQLFIGADGVDLT
ECCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSKVMAEVSREVIVMVESDKVGRKIPNLELAWEMIDILITNNDLLPEHK
CCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHEECCCCCCCHH
AEMEANGVRVICA
HHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]