Click here to switch to the map view.

The map label for this gene is cysN

Identifier: 37678596

GI number: 37678596

Start: 406319

End: 407749

Strand: Direct

Name: cysN

Synonym: VV0412

Alternate gene names: 37678596

Gene position: 406319-407749 (Clockwise)

Preceding gene: 37678595

Following gene: 37678597

Centisome position: 12.11

GC content: 49.13

Gene sequence:

>1431_bases
ATGAATAGTGCAGTTCAAGCTCAGCTCGCTGAGTTAGGTATTGAAGGTTACCTAAATCAACACCAACACAAATCGCTACT
TAGATTCCTCACATGTGGCTCGGTAGACGATGGTAAAAGTACCCTGATTGGTCGTTTACTACACGACTCAAAACAGATTT
ATGAAGATCAACTTGCGGCAGTGCATTCAGACAGTCAGCGCGTTGGCACCACGGGCAGTCGTCCAGACTTGGCGTTGCTA
GTGGATGGCCTACAAGCGGAGCGTGAGCAAGGCATCACCATCGATGTGGCTTACCGTTACTTCTCAACTCAGAAGCGTAA
ATTCATTATCGCCGATACTCCGGGGCATGAGCAGTACACGCGCAACATGGCAACAGGCGCTTCTACCTGTGACCTAGCGG
TGATTCTGATCGACGCGCGTAAAGGTGTGTTGGATCAAACGCGTCGCCACTCGTTTATCTCCAATTTGCTCGGCCTGAAA
CACTTTGTGGTTGCCGTGAACAAAATGGACTTAGTGGAGTTTTCTCAGCAACGCTTTGAAGAAATCAAAGCAGAGTACCT
AGCGTTTTCGAAAAATCTGCGCGGTGAAACGGATATTCAAATTATCCCCATCTCTGCTCTGGAAGGCGACAACGTGGTTG
AGCTGAGCCAACAAATGGCTTGGTACCAAGGCCCGACACTACTCGAAATTTTGGAAGCGGTTGACGTTGAGAAAGAGAAA
GAAGCGGGTGAATTCCGTTTCCCAGTGCAATACGTTAATCGTCCAAACCTCGATTTTCGTGGTTTCGCTGGCACCATTTC
GTCTGGTGTGGTGAAGGTGGGCGATCGCATTACGGCGTTGCCATCGGGTAAGAGCTCAACCGTTGCGCGCATCGTCACCT
TCGATGGCGATCTTGAACAGGCGCAAGCGGGTTTAGCGGTGACGCTGACTCTGGCCGATGAGATCGATATCAGCCGCGGG
GATTTGATTGTTCACCATGGTGCGAATGTGGAGCTCACTAACCATTTGGCTGCGGATGTGGTGTGGATGACAGAACAGCC
ACTTCAGCCTGGTCGTGATTATGACATCAAGATTGCTGGTAAAAAGACCATTGGTCGCGTTGAGCACATTCATCATCAAT
ATGACATCAACAACCTGTCTAAACACAGTGCGGCAGAGTTGCCATTGAATGGTATTGGTTTGTGTGAGTGGACCTTTAAT
GAGTCTATCGCTCTGGATAACTACCAAGACTGTGCTGATACCGGTGGTTTCATCATCATCGATCGCCTGACAAACGTCAC
TGTTGGCGCGGGCATGGTGAGTGAGAGCCTGACGGAAGTAACCAAAGCAAGCAGTGATTTCTCCGCATTTGAGTTGGAAT
TGAATGCACTCATTCGCAAGCATTTCCCACATTGGGATGCGAAAGATTTGAGCGAGCTGCTTAAGAAGTAA

Upstream 100 bases:

>100_bases
CTTCCAGTGAGCGTCAAGGACGAGCCATCGACCACGATCAATCGGGTTCGATGGAACTGAAAAAACGTCAGGGTTACTTC
TAAGGATCTAAGGAAAGAAA

Downstream 100 bases:

>100_bases
CACTAGAAGTAACACTGAGTCATACCGAAGTTTGTAGAGTCAGTCAGACGTTGTTGTAACTGGGGGAGTGAGACTCCCCC
ATCATGGGGATGTAGTATGT

Product: sulfate adenylyltransferase subunit 1

Products: NA

Alternate protein names: ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNSAVQAQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAAVHSDSQRVGTTGSRPDLALL
VDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLK
HFVVAVNKMDLVEFSQQRFEEIKAEYLAFSKNLRGETDIQIIPISALEGDNVVELSQQMAWYQGPTLLEILEAVDVEKEK
EAGEFRFPVQYVNRPNLDFRGFAGTISSGVVKVGDRITALPSGKSSTVARIVTFDGDLEQAQAGLAVTLTLADEIDISRG
DLIVHHGANVELTNHLAADVVWMTEQPLQPGRDYDIKIAGKKTIGRVEHIHHQYDINNLSKHSAAELPLNGIGLCEWTFN
ESIALDNYQDCADTGGFIIIDRLTNVTVGAGMVSESLTEVTKASSDFSAFELELNALIRKHFPHWDAKDLSELLKK

Sequences:

>Translated_476_residues
MNSAVQAQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAAVHSDSQRVGTTGSRPDLALL
VDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLK
HFVVAVNKMDLVEFSQQRFEEIKAEYLAFSKNLRGETDIQIIPISALEGDNVVELSQQMAWYQGPTLLEILEAVDVEKEK
EAGEFRFPVQYVNRPNLDFRGFAGTISSGVVKVGDRITALPSGKSSTVARIVTFDGDLEQAQAGLAVTLTLADEIDISRG
DLIVHHGANVELTNHLAADVVWMTEQPLQPGRDYDIKIAGKKTIGRVEHIHHQYDINNLSKHSAAELPLNGIGLCEWTFN
ESIALDNYQDCADTGGFIIIDRLTNVTVGAGMVSESLTEVTKASSDFSAFELELNALIRKHFPHWDAKDLSELLKK
>Mature_476_residues
MNSAVQAQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAAVHSDSQRVGTTGSRPDLALL
VDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLK
HFVVAVNKMDLVEFSQQRFEEIKAEYLAFSKNLRGETDIQIIPISALEGDNVVELSQQMAWYQGPTLLEILEAVDVEKEK
EAGEFRFPVQYVNRPNLDFRGFAGTISSGVVKVGDRITALPSGKSSTVARIVTFDGDLEQAQAGLAVTLTLADEIDISRG
DLIVHHGANVELTNHLAADVVWMTEQPLQPGRDYDIKIAGKKTIGRVEHIHHQYDINNLSKHSAAELPLNGIGLCEWTFN
ESIALDNYQDCADTGGFIIIDRLTNVTVGAGMVSESLTEVTKASSDFSAFELELNALIRKHFPHWDAKDLSELLKK

Specific function: May be the GTPase, regulating ATP sulfurylase activity [H]

COG id: COG2895

COG function: function code P; GTPases - Sulfate adenylate transferase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI223555963, Length=429, Percent_Identity=30.0699300699301, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI5729864, Length=429, Percent_Identity=30.0699300699301, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4503471, Length=325, Percent_Identity=30.7692307692308, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4503475, Length=325, Percent_Identity=29.5384615384615, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI194097354, Length=307, Percent_Identity=29.9674267100977, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI194018520, Length=307, Percent_Identity=29.9674267100977, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI194018522, Length=307, Percent_Identity=29.9674267100977, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI46094014, Length=307, Percent_Identity=29.6416938110749, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI34147630, Length=313, Percent_Identity=29.7124600638978, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1789108, Length=471, Percent_Identity=67.0912951167728, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1790412, Length=311, Percent_Identity=25.4019292604502, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789737, Length=311, Percent_Identity=25.4019292604502, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367247, Length=292, Percent_Identity=27.0547945205479, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532067, Length=316, Percent_Identity=30.379746835443, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115532065, Length=316, Percent_Identity=30.379746835443, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552884, Length=325, Percent_Identity=31.0769230769231, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17569207, Length=325, Percent_Identity=31.0769230769231, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI32566629, Length=310, Percent_Identity=31.6129032258064, Blast_Score=148, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI32566303, Length=318, Percent_Identity=29.559748427673, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI25141371, Length=285, Percent_Identity=27.3684210526316, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566301, Length=138, Percent_Identity=36.231884057971, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=346, Percent_Identity=27.7456647398844, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322937, Length=380, Percent_Identity=31.0526315789474, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6325337, Length=323, Percent_Identity=30.6501547987616, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319594, Length=323, Percent_Identity=30.6501547987616, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320377, Length=437, Percent_Identity=26.7734553775744, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324761, Length=241, Percent_Identity=29.8755186721992, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323320, Length=218, Percent_Identity=30.2752293577982, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652838, Length=305, Percent_Identity=31.1475409836066, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI17137572, Length=305, Percent_Identity=31.1475409836066, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI45553807, Length=275, Percent_Identity=32.7272727272727, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI45553816, Length=275, Percent_Identity=32.7272727272727, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24651721, Length=275, Percent_Identity=32.7272727272727, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI17864154, Length=275, Percent_Identity=32.7272727272727, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI45550900, Length=443, Percent_Identity=25.9593679458239, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17137380, Length=330, Percent_Identity=29.0909090909091, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI281363316, Length=325, Percent_Identity=28.3076923076923, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17864358, Length=325, Percent_Identity=28.3076923076923, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921738, Length=325, Percent_Identity=25.5384615384615, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4 [H]

Molecular weight: Translated: 52659; Mature: 52659

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSAVQAQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAA
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VHSDSQRVGTTGSRPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYT
HCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCHHHH
RNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLKHFVVAVNKMDLVEFSQQRFE
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EIKAEYLAFSKNLRGETDIQIIPISALEGDNVVELSQQMAWYQGPTLLEILEAVDVEKEK
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
EAGEFRFPVQYVNRPNLDFRGFAGTISSGVVKVGDRITALPSGKSSTVARIVTFDGDLEQ
CCCCEECCHHHCCCCCCCCCCCCCHHHCCEEECCCEEEECCCCCCCCEEEEEEECCCHHH
AQAGLAVTLTLADEIDISRGDLIVHHGANVELTNHLAADVVWMTEQPLQPGRDYDIKIAG
HCCCEEEEEEEECCCCCCCCCEEEECCCCEEECCHHHHEEEEECCCCCCCCCCCEEEEEC
KKTIGRVEHIHHQYDINNLSKHSAAELPLNGIGLCEWTFNESIALDNYQDCADTGGFIII
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCHHHHCCCCEEEE
DRLTNVTVGAGMVSESLTEVTKASSDFSAFELELNALIRKHFPHWDAKDLSELLKK
EECCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNSAVQAQLAELGIEGYLNQHQHKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYEDQLAA
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VHSDSQRVGTTGSRPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYT
HCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCHHHH
RNMATGASTCDLAVILIDARKGVLDQTRRHSFISNLLGLKHFVVAVNKMDLVEFSQQRFE
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EIKAEYLAFSKNLRGETDIQIIPISALEGDNVVELSQQMAWYQGPTLLEILEAVDVEKEK
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
EAGEFRFPVQYVNRPNLDFRGFAGTISSGVVKVGDRITALPSGKSSTVARIVTFDGDLEQ
CCCCEECCHHHCCCCCCCCCCCCCHHHCCEEECCCEEEECCCCCCCCEEEEEEECCCHHH
AQAGLAVTLTLADEIDISRGDLIVHHGANVELTNHLAADVVWMTEQPLQPGRDYDIKIAG
HCCCEEEEEEEECCCCCCCCCEEEECCCCEEECCHHHHEEEEECCCCCCCCCCCEEEEEC
KKTIGRVEHIHHQYDINNLSKHSAAELPLNGIGLCEWTFNESIALDNYQDCADTGGFIII
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCHHHHCCCCEEEE
DRLTNVTVGAGMVSESLTEVTKASSDFSAFELELNALIRKHFPHWDAKDLSELLKK
EECCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA