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The map label for this gene is secY

Identifier: 37678579

GI number: 37678579

Start: 393234

End: 394568

Strand: Direct

Name: secY

Synonym: VV0395

Alternate gene names: 37678579

Gene position: 393234-394568 (Clockwise)

Preceding gene: 37678578

Following gene: 37678580

Centisome position: 11.72

GC content: 44.64

Gene sequence:

>1335_bases
ATGGCTAAGAAACCAGGACAAGATTTTCGTAGTGCTCAGAGCGGCTTAAGTGAACTGAAGTCGCGCTTATTATTCGTAAT
TGGTGCACTTTTAGTATTCCGAGCTGGCTCTTTTGTGCCGATTCCTGGTATTGACGCTGCTGTACTTGCCGATTTGTTCG
AACAGCAAAAAGGTACCATCGTTGAAATGTTTAACATGTTCTCCGGTGGTGCTCTTGAGCGTGCATCTATTTTAGCTCTG
GGCATCATGCCGTATATTTCGGCATCTATTGTTGTCCAGTTGCTAACTGTAGTTCATCCAGCGTTAGCTGAACTCAAGAA
AGAGGGTGAAGCAGGCCGTCGTAAGATCAGCCAATACACACGCTACGGCACGCTTGTACTTGCAACATTCCAGGCTATTG
GTATTGCAACTGGCTTACCAAACATGGTCGACAATCTGGTCGTTATCGATCAAACCATGTTTACGCTAATTGCAACCGTG
AGTTTAGTAACCGGTACCATGTTCTTAATGTGGTTAGGTGAACAAATTACTGAGCGTGGAATTGGTAATGGTATTTCATT
ACTGATCTTTGCAGGTATTGTTGCTGGATTGCCTTCGGCAATCGGTCAAACAATCGAGCAAGCGCGTCAAGGTGAATTGC
ATGTACTTCTTCTGCTGTTAATTGCAGTTTTGGCTTTTGCTGTAATTTACTTCGTTGTTTTCATGGAGCGTGGTCAACGT
CGTATCGTTGTTAACTACGCGAAGCGTCAACAAGGTCGTAAAGTATTTGCAGCACAAAGCTCGCACCTTCCATTGAAAAT
TAATATGGCTGGTGTAATTCCTGCGATTTTCGCATCAAGCATTATCCTGTTCCCTGGAACATTGGCCCAGTGGTTCGGTC
AGAATGGTGAAAGCAGCGCGTTCGGTTGGTTAACTGACGTGTCATTGGCTCTAAGTCCTGGTCAACCGCTATATGTAATG
CTTTATGCAGCAGCGATTATTTTCTTCTGTTTCTTCTACACGGCGTTGGTTTTCAACCCGCGTGAAACAGCAGATAACCT
GAAGAAGTCAGGTGCATTCGTACCCGGTATCCGCCCAGGCGAGCAGACAGCCAAGTACATTGATAAAGTAATGACGCGTT
TAACCTTAGCTGGTGCGCTTTATATTACCTTTATCTGTCTGATTCCGGAGTTCATGATGGTCGCGTGGAACGTACGTTTC
TACTTCGGCGGTACATCACTACTTATCGTAGTTGTTGTAATTATGGACTTTATGGCACAGGTACAGACACATATGATGTC
TCATCAATATGAGTCTGTGTTGAAGAAAGCGAATCTGAAAGGCTACGGCCGTTAA

Upstream 100 bases:

>100_bases
CAGTGACTGTTAAAGGTCTACGTGTGACTAAAGGCGCTAAAGCTGCAATCGAAGCTGCAGGCGGTAAAATCGAGGAATAA
TCTCGAGGAACGAGGTACAG

Downstream 100 bases:

>100_bases
TCCGGCGGTAGTTTCAGTTTCAATTACGGAGTTTAGCAATGAAAGTTCGTGCTTCCGTTAAAAAAATCTGCCGTAACTGT
AAAGTAATCAAGCGTAACGG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAKKPGQDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQKGTIVEMFNMFSGGALERASILAL
GIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVIDQTMFTLIATV
SLVTGTMFLMWLGEQITERGIGNGISLLIFAGIVAGLPSAIGQTIEQARQGELHVLLLLLIAVLAFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVM
LYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRF
YFGGTSLLIVVVVIMDFMAQVQTHMMSHQYESVLKKANLKGYGR

Sequences:

>Translated_444_residues
MAKKPGQDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQKGTIVEMFNMFSGGALERASILAL
GIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVIDQTMFTLIATV
SLVTGTMFLMWLGEQITERGIGNGISLLIFAGIVAGLPSAIGQTIEQARQGELHVLLLLLIAVLAFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVM
LYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRF
YFGGTSLLIVVVVIMDFMAQVQTHMMSHQYESVLKKANLKGYGR
>Mature_443_residues
AKKPGQDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQKGTIVEMFNMFSGGALERASILALG
IMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVIDQTMFTLIATVS
LVTGTMFLMWLGEQITERGIGNGISLLIFAGIVAGLPSAIGQTIEQARQGELHVLLLLLIAVLAFAVIYFVVFMERGQRR
IVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVML
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRFY
FGGTSLLIVVVVIMDFMAQVQTHMMSHQYESVLKKANLKGYGR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=446, Percent_Identity=81.6143497757848, Blast_Score=677, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48522; Mature: 48391

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKKPGQDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFEQQKGTI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHH
VEMFNMFSGGALERASILALGIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGTLVLATFQAIGIATGLPNMVDNLVVIDQTMFTLIATVSLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISLLIFAGIVAGLPSAIGQTIEQARQGELHVLLLLLIAVLAFAVIYFVVFMERGQR
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSA
EEEEEHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
FGWLTDVSLALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPG
CHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
EQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRFYFGGTSLLIVVVVIMDFMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VQTHMMSHQYESVLKKANLKGYGR
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]