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The map label for this gene is murI [H]

Identifier: 37678352

GI number: 37678352

Start: 176142

End: 176933

Strand: Direct

Name: murI [H]

Synonym: VV0168

Alternate gene names: 37678352

Gene position: 176142-176933 (Clockwise)

Preceding gene: 37678351

Following gene: 37678356

Centisome position: 5.25

GC content: 47.6

Gene sequence:

>792_bases
GTGGAAAGTTCAAATCAGCCGAATGTATTGATTTTTGATTCCGGTGTTGGCGGGTTGTCGGTTTTTCAGGAAATCAACAA
ACGACTGCCTGAAGTGAACTACTACTATTTGTTTGATAACCAAGCCTATCCCTATGGCGAACTATCGCAAGAAACCTTAC
TGGCAAGAGTGGAAGCGCTGGTGGTCAAAATGACACAGCAATTTGCGATAGACCTTGTCGTCATTGCCTGCAACACTGCC
AGCACCATTGTACTCCCCGCCTTAAGAGCGAAGTTGCCTATTCCAGTTGTTGGTGTCGTGCCAGCGATCAAACCGGCTTC
TCTTTTGGCGAATCGAGCCGTGGGTTTAATTGCAACGCCAGCAACGGTGACTCGTCAATACACACACGACCTCATCCGTG
ATTTCGCGCATGAGAAAGAAGTTGAGTTACTTGGTTCGACTCGATTGGTGGACATCGCCGAAGAGAAACTAAGAGGGCGT
CAAGTCGATCAGCAAGAGCTGGCAATGATACTCAAACCGATGAAACACAAAGTGGACGTGGCGGTATTAGGATGCACCCA
TTTCCCATTGCTAAAAGAAGAAATACAGCAAGTGCTGGGTGATGAGATCATTTTGGTTGATTCTGGAGAAGCGATTGCTC
GTCGAGTGCAGAGCCTCCTCCATCAATTATCACCACAAAGTACCAAGACACCGTGGCGCATCTTTAGCACAGCGCAGCCT
TGGGATGAAGCTGCGCTGAATGGGTCACTAAAAACGATGGGGTTTAACGCTATAGAACTTTATCCTCTATAG

Upstream 100 bases:

>100_bases
AACCGATGGACGATTCACCTATCAAAGGTATAACGCAACGTTGCTAAATCAGCATGAGAGAGTATGATTTGGTCGTTTTA
TTCTAAGTAGGTTTATCAGA

Downstream 100 bases:

>100_bases
GGTGTTTCATTTCATTTGCAATGCGAACTTTCAATGTACGTTGCGCATACTCCTTTTCATTAAGTGCATTGATAGCATTT
TCTGCATCTCCACTGGCCAT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEALVVKMTQQFAIDLVVIACNTA
STIVLPALRAKLPIPVVGVVPAIKPASLLANRAVGLIATPATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGR
QVDQQELAMILKPMKHKVDVAVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQP
WDEAALNGSLKTMGFNAIELYPL

Sequences:

>Translated_263_residues
MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEALVVKMTQQFAIDLVVIACNTA
STIVLPALRAKLPIPVVGVVPAIKPASLLANRAVGLIATPATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGR
QVDQQELAMILKPMKHKVDVAVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQP
WDEAALNGSLKTMGFNAIELYPL
>Mature_263_residues
MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEALVVKMTQQFAIDLVVIACNTA
STIVLPALRAKLPIPVVGVVPAIKPASLLANRAVGLIATPATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGR
QVDQQELAMILKPMKHKVDVAVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQP
WDEAALNGSLKTMGFNAIELYPL

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=262, Percent_Identity=50.763358778626, Blast_Score=225, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 29126; Mature: 29126

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00923 ASP_GLU_RACEMASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEAL
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
VVKMTQQFAIDLVVIACNTASTIVLPALRAKLPIPVVGVVPAIKPASLLANRAVGLIATP
HHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHCCCEEEECC
ATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGRQVDQQELAMILKPMKHKVDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCE
AVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQP
EEECCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
WDEAALNGSLKTMGFNAIELYPL
HHHHHHCCCEEECCCCEEEEEEC
>Mature Secondary Structure
MESSNQPNVLIFDSGVGGLSVFQEINKRLPEVNYYYLFDNQAYPYGELSQETLLARVEAL
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
VVKMTQQFAIDLVVIACNTASTIVLPALRAKLPIPVVGVVPAIKPASLLANRAVGLIATP
HHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHCCCEEEECC
ATVTRQYTHDLIRDFAHEKEVELLGSTRLVDIAEEKLRGRQVDQQELAMILKPMKHKVDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCE
AVLGCTHFPLLKEEIQQVLGDEIILVDSGEAIARRVQSLLHQLSPQSTKTPWRIFSTAQP
EEECCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
WDEAALNGSLKTMGFNAIELYPL
HHHHHHCCCEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA