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The map label for this gene is ftsY [H]

Identifier: 37678296

GI number: 37678296

Start: 120110

End: 121423

Strand: Direct

Name: ftsY [H]

Synonym: VV0112

Alternate gene names: 37678296

Gene position: 120110-121423 (Clockwise)

Preceding gene: 37678293

Following gene: 37678297

Centisome position: 3.58

GC content: 49.92

Gene sequence:

>1314_bases
GTGACAAAGTGTACCATTATTCCGCCGAGAAAAACGGATCACATGCGTATACCAGTCGCGATTGTCTCTTTGCCTGCGCA
TCAGCAAAGATTCAACCCAGTATATAAGAAACCAGGATATCTCCCGATGACGGAAAAGAAAAAGCGCGGATTACTATCGT
GGCTTGGCTTTGGTGACGATGACCAAGTAAAACAACCAGAGCCGGCACAATCAGAAGAGGTGATCAGCGAGTCTGACGAA
AAAACCGTAGAGAGCGTTGAACCGATTGCCAGTCAAGAAGTGGTTGAAGAGGCGGCGGCAGAGCCAATCAGCGAACCAGC
AGCTGAAGAACCCGTTGAAGCGACACCTGTGGTGGTTGAAGCACCGCGCGTGCAAGAACAAGAAAAACCAACAGAAAGCT
TTTTTGCGCGTCTAAAACGCAGCTTGAGCCGCACGAAAGCCAATATCGGCGCGGGTTTCTTTGGCCTATTTAAAGGCAAG
AAAATCGATGATGATCTGTTTGAAGAGCTGGAAGAACAGCTACTCGTTGCGGATGTGGGTATGGATACCACGTTGAAAAT
CATCGAAAACTTAACAGAAAAAGCGTCTCGCCGTGACTTAAAAGATGGTGAGGCTCTGTATGGTTTGCTCAAAGAAGAGA
TGGCGGAGATCCTCTCTAAGGTTGAGCAACCATTGCAAGTGGACAGCAGCAAAACCCCTTACGTTATCCTGATGGTTGGG
GTAAATGGCGTGGGTAAGACCACCACCATTGGTAAGTTGGCGAAACAGTTCCAGAATCAAGGTAAGAAAGTGATGTTGGC
GGCGGGCGATACTTTCCGTGCGGCGGCCGTTGAGCAGTTGCAAGTGTGGGGTGAGCGCAACAATGTCCCAGTGATTGCAC
AGCACACTGGCGCAGACAGCGCATCGGTGATTTATGATGCGATTGAAGCCGCCAAAGCGCGTGGCGTTGATGTGGTGATC
GCCGATACTGCGGGTCGCTTGCAGAATAAGAGCAACTTGATGGAAGAGCTGCGCAAAATTGTCCGAGTGATGAAGAAAAT
CGACGACTCTGCACCGCATGAAATCATGTTGACCTTGGATGCGGGCACTGGTCAGAACGCCATCAGCCAAGCGAAACTGT
TTAGCGATGTCGCGCCGATCACCGGGATCACCTTGACCAAACTGGATGGCACTGCGAAAGGCGGCGTGATCTTTGCTATT
GCCGATCAGTTTAACATTCCTATTCGTTACATCGGTGTGGGTGAAGGGATTGAGGATCTCCGCCCGTTTGAAACCCAAGA
ATTTATCGACGCGCTATTTAGTCGAGAAGAGTAA

Upstream 100 bases:

>100_bases
TTGCTGGCGACGTCTTACCATAGATTTTTTGACCGCTAATAAAGTGTTACTATAGCCAATCGCCCAGGCCTAAAGCCTGG
ATATTGCCCAGAATTTGATA

Downstream 100 bases:

>100_bases
GCATTAGAGAGGAATAACCGGTGATCCGATTTCAGCAGGTAAGTAAAGCCTATCGTGGCGGCCGTCAGGCCCTGCAAAAA
GTCGACTTTCATTTACGTCG

Product: signal recognition particle GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTKCTIIPPRKTDHMRIPVAIVSLPAHQQRFNPVYKKPGYLPMTEKKKRGLLSWLGFGDDDQVKQPEPAQSEEVISESDE
KTVESVEPIASQEVVEEAAAEPISEPAAEEPVEATPVVVEAPRVQEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGK
KIDDDLFEELEEQLLVADVGMDTTLKIIENLTEKASRRDLKDGEALYGLLKEEMAEILSKVEQPLQVDSSKTPYVILMVG
VNGVGKTTTIGKLAKQFQNQGKKVMLAAGDTFRAAAVEQLQVWGERNNVPVIAQHTGADSASVIYDAIEAAKARGVDVVI
ADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAI
ADQFNIPIRYIGVGEGIEDLRPFETQEFIDALFSREE

Sequences:

>Translated_437_residues
MTKCTIIPPRKTDHMRIPVAIVSLPAHQQRFNPVYKKPGYLPMTEKKKRGLLSWLGFGDDDQVKQPEPAQSEEVISESDE
KTVESVEPIASQEVVEEAAAEPISEPAAEEPVEATPVVVEAPRVQEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGK
KIDDDLFEELEEQLLVADVGMDTTLKIIENLTEKASRRDLKDGEALYGLLKEEMAEILSKVEQPLQVDSSKTPYVILMVG
VNGVGKTTTIGKLAKQFQNQGKKVMLAAGDTFRAAAVEQLQVWGERNNVPVIAQHTGADSASVIYDAIEAAKARGVDVVI
ADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAI
ADQFNIPIRYIGVGEGIEDLRPFETQEFIDALFSREE
>Mature_436_residues
TKCTIIPPRKTDHMRIPVAIVSLPAHQQRFNPVYKKPGYLPMTEKKKRGLLSWLGFGDDDQVKQPEPAQSEEVISESDEK
TVESVEPIASQEVVEEAAAEPISEPAAEEPVEATPVVVEAPRVQEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKK
IDDDLFEELEEQLLVADVGMDTTLKIIENLTEKASRRDLKDGEALYGLLKEEMAEILSKVEQPLQVDSSKTPYVILMVGV
NGVGKTTTIGKLAKQFQNQGKKVMLAAGDTFRAAAVEQLQVWGERNNVPVIAQHTGADSASVIYDAIEAAKARGVDVVIA
DTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIA
DQFNIPIRYIGVGEGIEDLRPFETQEFIDALFSREE

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=281, Percent_Identity=32.7402135231317, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226371618, Length=199, Percent_Identity=36.6834170854271, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI295424842, Length=333, Percent_Identity=27.9279279279279, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI23308697, Length=333, Percent_Identity=27.9279279279279, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=32.8671328671329, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789874, Length=314, Percent_Identity=78.6624203821656, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1788963, Length=299, Percent_Identity=32.7759197324415, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=215, Percent_Identity=30.6976744186047, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193206261, Length=320, Percent_Identity=29.375, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=37.6884422110553, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=31.1688311688312, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17647949, Length=294, Percent_Identity=30.6122448979592, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=27.5747508305648, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 47930; Mature: 47799

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKCTIIPPRKTDHMRIPVAIVSLPAHQQRFNPVYKKPGYLPMTEKKKRGLLSWLGFGDD
CCCEEECCCCCCCCEECCEEEEECCCHHHHCCCHHCCCCCCCCCCHHHCCHHHHCCCCCC
DQVKQPEPAQSEEVISESDEKTVESVEPIASQEVVEEAAAEPISEPAAEEPVEATPVVVE
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
APRVQEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLVADVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCC
MDTTLKIIENLTEKASRRDLKDGEALYGLLKEEMAEILSKVEQPLQVDSSKTPYVILMVG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VNGVGKTTTIGKLAKQFQNQGKKVMLAAGDTFRAAAVEQLQVWGERNNVPVIAQHTGADS
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCH
ASVIYDAIEAAKARGVDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLD
HHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
AGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFNIPIRYIGVGEGIEDL
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHC
RPFETQEFIDALFSREE
CCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TKCTIIPPRKTDHMRIPVAIVSLPAHQQRFNPVYKKPGYLPMTEKKKRGLLSWLGFGDD
CCEEECCCCCCCCEECCEEEEECCCHHHHCCCHHCCCCCCCCCCHHHCCHHHHCCCCCC
DQVKQPEPAQSEEVISESDEKTVESVEPIASQEVVEEAAAEPISEPAAEEPVEATPVVVE
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
APRVQEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDLFEELEEQLLVADVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCC
MDTTLKIIENLTEKASRRDLKDGEALYGLLKEEMAEILSKVEQPLQVDSSKTPYVILMVG
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VNGVGKTTTIGKLAKQFQNQGKKVMLAAGDTFRAAAVEQLQVWGERNNVPVIAQHTGADS
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCH
ASVIYDAIEAAKARGVDVVIADTAGRLQNKSNLMEELRKIVRVMKKIDDSAPHEIMLTLD
HHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
AGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFNIPIRYIGVGEGIEDL
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHC
RPFETQEFIDALFSREE
CCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]