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The map label for this gene is gap3 [H]

Identifier: 37678284

GI number: 37678284

Start: 111513

End: 112514

Strand: Direct

Name: gap3 [H]

Synonym: VV0100

Alternate gene names: 37678284

Gene position: 111513-112514 (Clockwise)

Preceding gene: 37678283

Following gene: 37678285

Centisome position: 3.32

GC content: 52.2

Gene sequence:

>1002_bases
ATGACTATCAAAGTGGGAATTAACGGATTTGGCCGTATTGGCCGCTTGGCAATGCGCGCGGCCTTTGATTGGCCAGAATT
GGAGTTTGTTTTAATTAATGATGTGGCGGGGGATGCCACCACATTGGGCCACCTACTGGAGTTCGATTCAGTGCAAGGGC
GCTGGCACCACGAGGTGACGGTGCAAGGTCAGCAATTGCACATCAATGGCCACGTGATTGAAACCACTCAACAGCGTGAC
ATCAGTGCGGTGGATTGGTCGGGCTGTGATGTGGTGATTGAAGCGACAGGCGTACATCGCAAAAGCCGCTTCCTTAATCA
ATACCTCGAGCAAGGCGTGAAACGTGTGGTGGTCAGCGCTCCAGTGAAAGAAGAGGGCATTGCCAATATTGTGGTGGGTG
TGAATGACGAGATCTTCAACCCAGAGCAGCACCGCATTGTGACTGCAGCCTCGTGCACCACCAACTGCATTGCGCCAGTG
GTGAAAGTGATTCACGAGAAACTCGGTATCGAACAAGCATCATTTACCACTATCCACGATCTCACCAACACGCAAACCAT
TCTTGATGCGCCGCACAAAGATTTGCGTCGTGCCCGTGCCTGCGGCATGAGCTTGATCCCGACGACCACAGGCAGTGCCA
CGGCGATTGTGGAAATTTTCCCAGAATTGAAAGATCGCATTAACGGTCACGCGGTGCGCGTGCCTCTAGCGAATGCCTCA
CTGACCGATATTATTTTTGATGTGAAGCGTGACACCACTGCCGAAGAGGTTAACGCCTTACTCAAAGAAGCCTCTCAAGG
GGAGTTAAACGGCATTCTCGGCTTTGAAGAGCGCCCATTGGTGTCGATTGATTATCGTGGCGACCAACGCTCAACCATCG
TCGATGCCCTCTCTACCATGGTGGTGGGTACACGCATGGTGAAGATTTACGCTTGGTATGATAACGAAATGGGCTATGCG
ACCCGTACCGCAGAGCTTGTGCGTAAAGTAGGAGCGGCATAA

Upstream 100 bases:

>100_bases
ACTGTTTAAAGCAAGTTTATCAACAAGATATTGCGCGCCTGCATCAACAAGATCGTGTGGCGTGCTGTTAAATTGAAATT
GAATCATTAGGGAATAGACC

Downstream 100 bases:

>100_bases
TGGAAACGTCAATCACCAACCACCCTGTTTGGCAATTGGACCTACCGTCTGGCGCATTGGTCTTAACACCTTGCCCTGGT
ACCAAAGGGGTCGATTTACG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTIKVGINGFGRIGRLAMRAAFDWPELEFVLINDVAGDATTLGHLLEFDSVQGRWHHEVTVQGQQLHINGHVIETTQQRD
ISAVDWSGCDVVIEATGVHRKSRFLNQYLEQGVKRVVVSAPVKEEGIANIVVGVNDEIFNPEQHRIVTAASCTTNCIAPV
VKVIHEKLGIEQASFTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAIVEIFPELKDRINGHAVRVPLANAS
LTDIIFDVKRDTTAEEVNALLKEASQGELNGILGFEERPLVSIDYRGDQRSTIVDALSTMVVGTRMVKIYAWYDNEMGYA
TRTAELVRKVGAA

Sequences:

>Translated_333_residues
MTIKVGINGFGRIGRLAMRAAFDWPELEFVLINDVAGDATTLGHLLEFDSVQGRWHHEVTVQGQQLHINGHVIETTQQRD
ISAVDWSGCDVVIEATGVHRKSRFLNQYLEQGVKRVVVSAPVKEEGIANIVVGVNDEIFNPEQHRIVTAASCTTNCIAPV
VKVIHEKLGIEQASFTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAIVEIFPELKDRINGHAVRVPLANAS
LTDIIFDVKRDTTAEEVNALLKEASQGELNGILGFEERPLVSIDYRGDQRSTIVDALSTMVVGTRMVKIYAWYDNEMGYA
TRTAELVRKVGAA
>Mature_332_residues
TIKVGINGFGRIGRLAMRAAFDWPELEFVLINDVAGDATTLGHLLEFDSVQGRWHHEVTVQGQQLHINGHVIETTQQRDI
SAVDWSGCDVVIEATGVHRKSRFLNQYLEQGVKRVVVSAPVKEEGIANIVVGVNDEIFNPEQHRIVTAASCTTNCIAPVV
KVIHEKLGIEQASFTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAIVEIFPELKDRINGHAVRVPLANASL
TDIIFDVKRDTTAEEVNALLKEASQGELNGILGFEERPLVSIDYRGDQRSTIVDALSTMVVGTRMVKIYAWYDNEMGYAT
RTAELVRKVGAA

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=328, Percent_Identity=39.0243902439024, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=37.0820668693009, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1789295, Length=327, Percent_Identity=41.5902140672783, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=39.3939393939394, Blast_Score=252, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=36.5269461077844, Blast_Score=237, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=36.5269461077844, Blast_Score=236, Evalue=9e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=35.9516616314199, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=35.3474320241692, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=39.2215568862275, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=38.622754491018, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=36.5269461077844, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=37.8048780487805, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=37.8048780487805, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=36.280487804878, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=36.890243902439, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=36.890243902439, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36619; Mature: 36488

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRLAMRAAFDWPELEFVLINDVAGDATTLGHLLEFDSVQGRWHHEVT
CEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEE
VQGQQLHINGHVIETTQQRDISAVDWSGCDVVIEATGVHRKSRFLNQYLEQGVKRVVVSA
EECCEEEECCEEEECCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEHCC
PVKEEGIANIVVGVNDEIFNPEQHRIVTAASCTTNCIAPVVKVIHEKLGIEQASFTTIHD
CCCCCCCEEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEHH
LTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAIVEIFPELKDRINGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
LTDIIFDVKRDTTAEEVNALLKEASQGELNGILGFEERPLVSIDYRGDQRSTIVDALSTM
HHHHEEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHH
VVGTRMVKIYAWYDNEMGYATRTAELVRKVGAA
HHCEEEEEEEEEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIKVGINGFGRIGRLAMRAAFDWPELEFVLINDVAGDATTLGHLLEFDSVQGRWHHEVT
EEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEE
VQGQQLHINGHVIETTQQRDISAVDWSGCDVVIEATGVHRKSRFLNQYLEQGVKRVVVSA
EECCEEEECCEEEECCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEHCC
PVKEEGIANIVVGVNDEIFNPEQHRIVTAASCTTNCIAPVVKVIHEKLGIEQASFTTIHD
CCCCCCCEEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEHH
LTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAIVEIFPELKDRINGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
LTDIIFDVKRDTTAEEVNALLKEASQGELNGILGFEERPLVSIDYRGDQRSTIVDALSTM
HHHHEEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHH
VVGTRMVKIYAWYDNEMGYATRTAELVRKVGAA
HHCEEEEEEEEEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]