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The map label for this gene is dppC [H]

Identifier: 37678230

GI number: 37678230

Start: 55365

End: 56303

Strand: Direct

Name: dppC [H]

Synonym: VV0046

Alternate gene names: 37678230

Gene position: 55365-56303 (Clockwise)

Preceding gene: 37678229

Following gene: 37678231

Centisome position: 1.65

GC content: 51.01

Gene sequence:

>939_bases
ATGGAACACGTTAATAAAGCTCCTTCTGCATGGGAACGCTTTAAAGAATCGGATTTTCTTTACTATTTTAAACGCGACAA
AGTGGCGATGAGCAGCTTCGCGGTGTTCATGCTGTTTTTGCTGTTGGCGATTGCCGCGCCGTTAATCGCGCCGAGCAATC
CCTATGATCTCTCATCGATTGACATTATGGACGCGGAGCTGCCGCCATCTTGGATGGAAGGCGGTGATGAAAACTTCGTG
CTGGGCACCGATGAGCAAGGTCGCGATATTCTTTCCACCATCTTATATGGCTCGCGTCTGTCGCTCACCATTGGCTTCTT
GGCGGTGGCGCTGCAGCTGTTTTTGGGCATCGTGATTGGCCTGTCGGCGGGTTACTTTGGTGGTCGCATTGACAACTTTC
TGATGCGTTTTGCGGATGTTCAGCTCTCCTTCTCGACCATGATGGTAGCGATTATTGTCTCAGCCATCTTTAAAGCCAGT
TTCGGCAGCGATTTCTATAGTCAATATGCGGTGGTGATGCTGGTGGTGATCATCGGTGTGGCGGAATGGCCACAATACGC
ACGTACGATTCGCGCCTCGGTATTGGCAGAGAAGAAGAAAGAGTACGTTGAAGCGGCACGCGTGATGGGCTTTAGGGCAC
CGCGCATCATGTTCCGTCATATTCTGCCGAACTGTTTGTCACCGATTTTGGTTATCTCAACCGTGCAAGTCGCTAACGCG
ATCATGTCGGAAGCGGCGCTCTCGTTCTTAGGGCTGGGTTTGCCCGTTGACCAACCGTCATTGGGCGCATTGATCAGCAT
TGGTTTTAACTACATCTTCTCCGGCGCTTGGTGGATCACCGCCTTCCCTGGCATTGTGCTGGTGACGCTGGTGTTAGTGA
TCAACCTATTGGGTGACTGGTTACGTGACGTATTTAACCCAAAAATCTACAAAGGGTGA

Upstream 100 bases:

>100_bases
TTTTTGTCGGACTGATTTTCGTGGTGACCAACACCATCGTTGACCTGCTGTATGGTTTAATCAACCCGACCGTGAACTTA
ACAGGCAAAGGAGCATAATC

Downstream 100 bases:

>100_bases
TCTGAGCTGATTGATTTATAATCGGAAAACTACCTAAACTAAGAGTCGTAAGCCAATTACGGCTCTTTTTTTGCTTGTCA
TTTTTTATTCACCAGGACGC

Product: peptide ABC transporter, permease component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEHVNKAPSAWERFKESDFLYYFKRDKVAMSSFAVFMLFLLLAIAAPLIAPSNPYDLSSIDIMDAELPPSWMEGGDENFV
LGTDEQGRDILSTILYGSRLSLTIGFLAVALQLFLGIVIGLSAGYFGGRIDNFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYSQYAVVMLVVIIGVAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGIVLVTLVLVINLLGDWLRDVFNPKIYKG

Sequences:

>Translated_312_residues
MEHVNKAPSAWERFKESDFLYYFKRDKVAMSSFAVFMLFLLLAIAAPLIAPSNPYDLSSIDIMDAELPPSWMEGGDENFV
LGTDEQGRDILSTILYGSRLSLTIGFLAVALQLFLGIVIGLSAGYFGGRIDNFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYSQYAVVMLVVIIGVAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGIVLVTLVLVINLLGDWLRDVFNPKIYKG
>Mature_312_residues
MEHVNKAPSAWERFKESDFLYYFKRDKVAMSSFAVFMLFLLLAIAAPLIAPSNPYDLSSIDIMDAELPPSWMEGGDENFV
LGTDEQGRDILSTILYGSRLSLTIGFLAVALQLFLGIVIGLSAGYFGGRIDNFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYSQYAVVMLVVIIGVAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGIVLVTLVLVINLLGDWLRDVFNPKIYKG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=296, Percent_Identity=41.554054054054, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1787760, Length=303, Percent_Identity=31.6831683168317, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787054, Length=297, Percent_Identity=32.6599326599327, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=286, Percent_Identity=33.9160839160839, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789889, Length=257, Percent_Identity=31.5175097276265, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788505, Length=241, Percent_Identity=30.7053941908714, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787549, Length=236, Percent_Identity=31.7796610169492, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34488; Mature: 34488

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVNKAPSAWERFKESDFLYYFKRDKVAMSSFAVFMLFLLLAIAAPLIAPSNPYDLSSI
CCCCCCCHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DIMDAELPPSWMEGGDENFVLGTDEQGRDILSTILYGSRLSLTIGFLAVALQLFLGIVIG
EEECCCCCCHHHCCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSAGYFGGRIDNFLMRFADVQLSFSTMMVAIIVSAIFKASFGSDFYSQYAVVMLVVIIGV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGIVLVTLVLVINLLGDW
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRDVFNPKIYKG
HHHHCCCCCCCC
>Mature Secondary Structure
MEHVNKAPSAWERFKESDFLYYFKRDKVAMSSFAVFMLFLLLAIAAPLIAPSNPYDLSSI
CCCCCCCHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DIMDAELPPSWMEGGDENFVLGTDEQGRDILSTILYGSRLSLTIGFLAVALQLFLGIVIG
EEECCCCCCHHHCCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSAGYFGGRIDNFLMRFADVQLSFSTMMVAIIVSAIFKASFGSDFYSQYAVVMLVVIIGV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGIVLVTLVLVINLLGDW
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRDVFNPKIYKG
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]