Click here to switch to the map view.

The map label for this gene is trkH [H]

Identifier: 37678215

GI number: 37678215

Start: 30291

End: 31748

Strand: Direct

Name: trkH [H]

Synonym: VV0031

Alternate gene names: 37678215

Gene position: 30291-31748 (Clockwise)

Preceding gene: 37678214

Following gene: 37678216

Centisome position: 0.9

GC content: 48.77

Gene sequence:

>1458_bases
ATGCAATTTCGTTCAATTATCCGTATTGTCGGGCTGTTGCTCGCACTCTTCAGTGTCACTATGCTTGCGCCCGCGTTGGT
GGCGCTTATTTATCGCGATGGTGCGGGTGTTCCTTTTGTTACGACCTTTTTTGTGCTGCTGTTTTGCGGCACCGTGTGTT
GGTTTCCAAACCGTAGGCATAAACACGAACTCAAAGCGCGCGATGGCTTTTTAATTGTGGTGCTATTTTGGACCGTACTC
GGCAGTGCTGGTGCGTTGCCCTTCCTGATCGCTGATAACCCCAGTATTTCGATCACCGATGCGTTTTTCGAATCCTTCTC
CGCGCTGACCACCACGGGTGCGACGGTTATCGTCGGTTTAGATGAACTGCCCAAAGCGATTTTGTTCTATCGCCAGATAC
TGCAATGGTTTGGCGGTATGGGGATCATCGTGCTGGCGGTCGCGATTTTGCCGGTTCTAGGCATCGGTGGCATGCAGTTG
TATCGTGCAGAAATTCCTGGTCCAGTCAAAGACAGTAAAATGACCCCGCGTATTGCTGAAACGGCTAAAGCACTTTGGTA
TATCTATTTGAGTCTCACTATCGCTTGTGCGGGGGCTTTCTGGCTGGCGGGAATGACGCCGTTTGATGCGATTAGCCATA
GTTTCTCGACCATCGCGATTGGTGGCTTTTCTACCCACGACGCCAGTATGGGGTATTTCGATAGCTATGCGATTAACTTA
ATTACGGTTATCTTCCTGCTGATCTCGGCATGTAACTACTCACTTCACTTTGCCGCCTTTGCCTCTGGCGGTGTTCATCC
CAAATACTATTGGAAAGACCCAGAGTTTAGAGCATTTATCTTTATTCAAGCACTGCTGTTTGTCATTTGCTTCTTATTAT
TGTTGGCACACCATTCTTACGACTCCATTTACGATGCCTTCGACCAAGCGTTGTTCCAAACAGTTTCTATCTCAACTACT
GCGGGTTTCACCACCACGGGATTTTCAGATTGGCCACTATTTCTACCCGTGCTACTGCTGTTCTCCTCTTTTATTGGCGG
ATGTGCAGGCTCAACCGGTGGTGGTATGAAAGTCATTCGGATTTTATTGCTCACGTTGCAAGGTGCGCGTGAACTTAAGC
GCTTAGTTCACCCTAGAGCGGTCTACACCATCAAAGTGGGTGGCAATGCTCTGTCGCAACGTGTGGTGGATGCGGTGTGG
GGATTCTTCTCCGCTTATGCATTGGTGTTCGTCGTTTGTATGCTCGCACTTATTGCGACAGGAATGGACGAACTTACCGC
TTTTTCGGCCGTCGCAGCGACGCTAAACAACCTAGGCCCAGGCTTGGGGGAAGTTGCAGTGCATTTTGCGGATGTGAACG
ATAAAGCCAAATGGGTTTTGGTGGTGTCTATGCTCTTTGGTCGTTTAGAAATCTTTACCTTACTTATATTGCTAACCCCT
ACGTTTTGGCGCAGTTAA

Upstream 100 bases:

>100_bases
CATGATCAACAAAAGCAGTGCAAAAGCGCTCGTGACGCCTTATATCGGGAAATAACAATAACAACTAGGAAGTCTATCGA
CTTTATTGATTCAATCATCC

Downstream 100 bases:

>100_bases
GGAGAAATGATAGTGAAAGCCCTATTTCTTTATTCTTCCCGTGAGGGGCAGACCAAGAAAATCCTTCAATATATAGAAGA
ACAGTTACCGAGCTATCAAT

Product: Trk-type K+ transport system, membrane component

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQFRSIIRIVGLLLALFSVTMLAPALVALIYRDGAGVPFVTTFFVLLFCGTVCWFPNRRHKHELKARDGFLIVVLFWTVL
GSAGALPFLIADNPSISITDAFFESFSALTTTGATVIVGLDELPKAILFYRQILQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAGAFWLAGMTPFDAISHSFSTIAIGGFSTHDASMGYFDSYAINL
ITVIFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQALLFVICFLLLLAHHSYDSIYDAFDQALFQTVSISTT
AGFTTTGFSDWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGARELKRLVHPRAVYTIKVGGNALSQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELTAFSAVAATLNNLGPGLGEVAVHFADVNDKAKWVLVVSMLFGRLEIFTLLILLTP
TFWRS

Sequences:

>Translated_485_residues
MQFRSIIRIVGLLLALFSVTMLAPALVALIYRDGAGVPFVTTFFVLLFCGTVCWFPNRRHKHELKARDGFLIVVLFWTVL
GSAGALPFLIADNPSISITDAFFESFSALTTTGATVIVGLDELPKAILFYRQILQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAGAFWLAGMTPFDAISHSFSTIAIGGFSTHDASMGYFDSYAINL
ITVIFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQALLFVICFLLLLAHHSYDSIYDAFDQALFQTVSISTT
AGFTTTGFSDWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGARELKRLVHPRAVYTIKVGGNALSQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELTAFSAVAATLNNLGPGLGEVAVHFADVNDKAKWVLVVSMLFGRLEIFTLLILLTP
TFWRS
>Mature_485_residues
MQFRSIIRIVGLLLALFSVTMLAPALVALIYRDGAGVPFVTTFFVLLFCGTVCWFPNRRHKHELKARDGFLIVVLFWTVL
GSAGALPFLIADNPSISITDAFFESFSALTTTGATVIVGLDELPKAILFYRQILQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAGAFWLAGMTPFDAISHSFSTIAIGGFSTHDASMGYFDSYAINL
ITVIFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQALLFVICFLLLLAHHSYDSIYDAFDQALFQTVSISTT
AGFTTTGFSDWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGARELKRLVHPRAVYTIKVGGNALSQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELTAFSAVAATLNNLGPGLGEVAVHFADVNDKAKWVLVVSMLFGRLEIFTLLILLTP
TFWRS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=69.6907216494845, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=42.1161825726141, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52935; Mature: 52935

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFRSIIRIVGLLLALFSVTMLAPALVALIYRDGAGVPFVTTFFVLLFCGTVCWFPNRRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
KHELKARDGFLIVVLFWTVLGSAGALPFLIADNPSISITDAFFESFSALTTTGATVIVGL
HHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEEH
DELPKAILFYRQILQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLSLTIACAGAFWLAGMTPFDAISHSFSTIAIGGFSTHDASMGYFDSYAINL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
ITVIFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQALLFVICFLLLLAHHSY
HHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCH
DSIYDAFDQALFQTVSISTTAGFTTTGFSDWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLTLQGARELKRLVHPRAVYTIKVGGNALSQRVVDAVWGFFSAYALVFVVCMLALIAT
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDELTAFSAVAATLNNLGPGLGEVAVHFADVNDKAKWVLVVSMLFGRLEIFTLLILLTP
CHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRS
HHHCC
>Mature Secondary Structure
MQFRSIIRIVGLLLALFSVTMLAPALVALIYRDGAGVPFVTTFFVLLFCGTVCWFPNRRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
KHELKARDGFLIVVLFWTVLGSAGALPFLIADNPSISITDAFFESFSALTTTGATVIVGL
HHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEEH
DELPKAILFYRQILQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLSLTIACAGAFWLAGMTPFDAISHSFSTIAIGGFSTHDASMGYFDSYAINL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
ITVIFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQALLFVICFLLLLAHHSY
HHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCH
DSIYDAFDQALFQTVSISTTAGFTTTGFSDWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLTLQGARELKRLVHPRAVYTIKVGGNALSQRVVDAVWGFFSAYALVFVVCMLALIAT
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDELTAFSAVAATLNNLGPGLGEVAVHFADVNDKAKWVLVVSMLFGRLEIFTLLILLTP
CHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]