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The map label for this gene is mreB [H]

Identifier: 37523968

GI number: 37523968

Start: 4626394

End: 4627440

Strand: Direct

Name: mreB [H]

Synonym: glr4399

Alternate gene names: 37523968

Gene position: 4626394-4627440 (Clockwise)

Preceding gene: 37523967

Following gene: 37523969

Centisome position: 99.3

GC content: 65.43

Gene sequence:

>1047_bases
GTGGGCCTTTTCAGTCGGTTTTCCCGAGACATGGGAATCGACCTGGGTACAGCCAATACGCTGATCTACGTCGCCGGTCG
GGGCACGGTGCTCTTCGAGCCGAGTGTGGTCGCCCTCGACGAGCGCACCGGCAAAGCCCTGGCCTTCGGCGAAGCCGCCC
GGCAGATGCTCGGGCGCACCCCCGGCAGCGTTGTCACGATCCGGCCTTTGCGCGATGGGGTGATAGCCAACTTCGACGTC
ACCGAGATGATGCTTAAGCACTTTATCCAGCGCGTGCACAATGGGCAGTACCTTGTCTCCCCGCTGATTGTGATCGGGAT
TCCAAGCGGGGTGACCAGCATCGAGCGGCGGGCGGTGATGGAGGCGGCCATCCGGGCGGGGGCGCGGGAGGTGCGCCTTG
TGGACGAGCCGGTGGCGGCGGCTATCGGTGCCGGTTTGCCGGTGAGCGAACCGACCGGCACGATGATTGTCGATATCGGT
GGCGGTACGAGCGAAGTGGCGGTCCTCGCCCTCAAAGGCACGGTGCTCTCCGAGTCGGTGCGCGTCGCGGGCGACGAACT
CACCGAATCCATCGGCACCTATCTCAAGAAAGTGCACAACCTGGTAATTGGCGAGCGCACCGCCGAGGGGATCAAGATGC
AGTTGGGCACAGCCTATCCCCAGCGCGATGAGGCGGCCGGCAAAATGGAGGTGCGCGGCCTGCATCTGCTGTCGGGGTTG
CCGCGGACCGTGGTGGTCCGGGCGGCGGAGATCCGCGAAAGTATGCACGAACCGCTCTGCGCGATTGTGGAGGCGGTCAA
GCGCACCCTGGAGCGCACACCGCCGGAATTGGCCGCCGACATCGCCGATCGCGGCATCGTGCTGGCGGGGGGCGGAGCCC
TGCTGCGCGGTCTGGACGATTTGATTTCCGATGAAACGGGGGTAGCGGTGCACGTCGCCGAGAATCCGCTCGGTTGTGTG
GCCCTTGGCATCGGCCGCGTACTCGAAGACTTCCAGCGTTTGGAGCGGGTGCTGGGCGGCAGCATCAAGCGGCTGAGCGA
TCGATAG

Upstream 100 bases:

>100_bases
GGGGAAGTCGTCGAGCGCGTCTTTCGTCCGGAACCCTGAACAGACCGCGAATCTTCTCTGTGTTAGGATCCCCATCGAGT
CATCCGTGTGAGGGTGTTGC

Downstream 100 bases:

>100_bases
AGGGGTGCAGCGGTGGTTGAGCGGCTCAGGCGGTGGTGGATACGGTTTGGACTGGTCGCGGTGGCGGGGCTGCTGGCCTT
GGGTTTGGGCTGGTGGATGC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MGLFSRFSRDMGIDLGTANTLIYVAGRGTVLFEPSVVALDERTGKALAFGEAARQMLGRTPGSVVTIRPLRDGVIANFDV
TEMMLKHFIQRVHNGQYLVSPLIVIGIPSGVTSIERRAVMEAAIRAGAREVRLVDEPVAAAIGAGLPVSEPTGTMIVDIG
GGTSEVAVLALKGTVLSESVRVAGDELTESIGTYLKKVHNLVIGERTAEGIKMQLGTAYPQRDEAAGKMEVRGLHLLSGL
PRTVVVRAAEIRESMHEPLCAIVEAVKRTLERTPPELAADIADRGIVLAGGGALLRGLDDLISDETGVAVHVAENPLGCV
ALGIGRVLEDFQRLERVLGGSIKRLSDR

Sequences:

>Translated_348_residues
MGLFSRFSRDMGIDLGTANTLIYVAGRGTVLFEPSVVALDERTGKALAFGEAARQMLGRTPGSVVTIRPLRDGVIANFDV
TEMMLKHFIQRVHNGQYLVSPLIVIGIPSGVTSIERRAVMEAAIRAGAREVRLVDEPVAAAIGAGLPVSEPTGTMIVDIG
GGTSEVAVLALKGTVLSESVRVAGDELTESIGTYLKKVHNLVIGERTAEGIKMQLGTAYPQRDEAAGKMEVRGLHLLSGL
PRTVVVRAAEIRESMHEPLCAIVEAVKRTLERTPPELAADIADRGIVLAGGGALLRGLDDLISDETGVAVHVAENPLGCV
ALGIGRVLEDFQRLERVLGGSIKRLSDR
>Mature_347_residues
GLFSRFSRDMGIDLGTANTLIYVAGRGTVLFEPSVVALDERTGKALAFGEAARQMLGRTPGSVVTIRPLRDGVIANFDVT
EMMLKHFIQRVHNGQYLVSPLIVIGIPSGVTSIERRAVMEAAIRAGAREVRLVDEPVAAAIGAGLPVSEPTGTMIVDIGG
GTSEVAVLALKGTVLSESVRVAGDELTESIGTYLKKVHNLVIGERTAEGIKMQLGTAYPQRDEAAGKMEVRGLHLLSGLP
RTVVVRAAEIRESMHEPLCAIVEAVKRTLERTPPELAADIADRGIVLAGGGALLRGLDDLISDETGVAVHVAENPLGCVA
LGIGRVLEDFQRLERVLGGSIKRLSDR

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=328, Percent_Identity=56.7073170731707, Blast_Score=348, Evalue=3e-97,
Organism=Escherichia coli, GI1786870, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36921; Mature: 36790

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFSRFSRDMGIDLGTANTLIYVAGRGTVLFEPSVVALDERTGKALAFGEAARQMLGRT
CCCHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCC
PGSVVTIRPLRDGVIANFDVTEMMLKHFIQRVHNGQYLVSPLIVIGIPSGVTSIERRAVM
CCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCEEECCEEEEECCCCHHHHHHHHHH
EAAIRAGAREVRLVDEPVAAAIGAGLPVSEPTGTMIVDIGGGTSEVAVLALKGTVLSESV
HHHHHCCCHHEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECHHHHHHH
RVAGDELTESIGTYLKKVHNLVIGERTAEGIKMQLGTAYPQRDEAAGKMEVRGLHLLSGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEECHHHHHHCC
PRTVVVRAAEIRESMHEPLCAIVEAVKRTLERTPPELAADIADRGIVLAGGGALLRGLDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHHH
LISDETGVAVHVAENPLGCVALGIGRVLEDFQRLERVLGGSIKRLSDR
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
GLFSRFSRDMGIDLGTANTLIYVAGRGTVLFEPSVVALDERTGKALAFGEAARQMLGRT
CCHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCC
PGSVVTIRPLRDGVIANFDVTEMMLKHFIQRVHNGQYLVSPLIVIGIPSGVTSIERRAVM
CCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCEEECCEEEEECCCCHHHHHHHHHH
EAAIRAGAREVRLVDEPVAAAIGAGLPVSEPTGTMIVDIGGGTSEVAVLALKGTVLSESV
HHHHHCCCHHEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECHHHHHHH
RVAGDELTESIGTYLKKVHNLVIGERTAEGIKMQLGTAYPQRDEAAGKMEVRGLHLLSGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEECHHHHHHCC
PRTVVVRAAEIRESMHEPLCAIVEAVKRTLERTPPELAADIADRGIVLAGGGALLRGLDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHHH
LISDETGVAVHVAENPLGCVALGIGRVLEDFQRLERVLGGSIKRLSDR
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]