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The map label for this gene is yfcG [H]

Identifier: 37523941

GI number: 37523941

Start: 4604666

End: 4605277

Strand: Direct

Name: yfcG [H]

Synonym: glr4372

Alternate gene names: 37523941

Gene position: 4604666-4605277 (Clockwise)

Preceding gene: 37523940

Following gene: 37523944

Centisome position: 98.83

GC content: 60.13

Gene sequence:

>612_bases
ATGATCGACCTTTACACGTTCACCACTCCCAATGGCCGCAAAGTCTCGGTGATGCTGGAGGAAGTGGGCCTGCCCTACAC
CGTCCATGTCGTGGACATCTCCAGCGGCGACCAGCACCGGGAAGAGTACCTGGCCATCAACCCGAACGGCAAAATTCCGG
CTATTATCGACCACGACACGGGGCTCACGATCTTCGAATCCGGGGCCATCTTGATCTATCTGGCTGAAAAGACCGGCAAA
TTGCTGCCGAGCGAACCCGCTGCCCGCTACGCCGCTTTGCAGTGGCTGATGTGGCAGATGGGCGGGGTGGGACCGATGTT
CGGACAGCTCAACCACTTCAAGCGCTTCGCCGACGAGCACGTTCCCTACGCCATCGATCGCTACTTTCGCGAGAGCATCC
GCCTCTACCGGGTGCTCAACCGGCAGTTGAGCCGCAATCTTTACGTAGCGGGCCGCGAGTATACGATCGCCGATGTAGCC
ATTTTCCCCTGGGTGCAGATCCACGCATTCCAGGGCATCATCCTCGAAGATTTTCCCGCCGTCGAAGTGTGGTTCGAGCG
GCTCAAAGCCCGACCCGCCGTGCAACGGGGTATGCAGGTGCCCGCGCCGTAG

Upstream 100 bases:

>100_bases
AGGAGCACTGGCTTATCCACCAGGTGAGCCGGGGGGTGAAACCCATCTGGCGACCCGGGCTCGCCTATGCTGAAACTCGT
CCGCAACCTTCCGAAGCGCC

Downstream 100 bases:

>100_bases
ACAGTTGGGCCGCTGGCACAAAGTCGCTTTTTTCTACAGCTGTCCGCACCTAGAATCTCGACACCTATCGGATCATCCCG
ATGAACAGACAGATGGAGTG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIDLYTFTTPNGRKVSVMLEEVGLPYTVHVVDISSGDQHREEYLAINPNGKIPAIIDHDTGLTIFESGAILIYLAEKTGK
LLPSEPAARYAALQWLMWQMGGVGPMFGQLNHFKRFADEHVPYAIDRYFRESIRLYRVLNRQLSRNLYVAGREYTIADVA
IFPWVQIHAFQGIILEDFPAVEVWFERLKARPAVQRGMQVPAP

Sequences:

>Translated_203_residues
MIDLYTFTTPNGRKVSVMLEEVGLPYTVHVVDISSGDQHREEYLAINPNGKIPAIIDHDTGLTIFESGAILIYLAEKTGK
LLPSEPAARYAALQWLMWQMGGVGPMFGQLNHFKRFADEHVPYAIDRYFRESIRLYRVLNRQLSRNLYVAGREYTIADVA
IFPWVQIHAFQGIILEDFPAVEVWFERLKARPAVQRGMQVPAP
>Mature_203_residues
MIDLYTFTTPNGRKVSVMLEEVGLPYTVHVVDISSGDQHREEYLAINPNGKIPAIIDHDTGLTIFESGAILIYLAEKTGK
LLPSEPAARYAALQWLMWQMGGVGPMFGQLNHFKRFADEHVPYAIDRYFRESIRLYRVLNRQLSRNLYVAGREYTIADVA
IFPWVQIHAFQGIILEDFPAVEVWFERLKARPAVQRGMQVPAP

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=203, Percent_Identity=51.2315270935961, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI87082195, Length=211, Percent_Identity=39.8104265402844, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87081789, Length=206, Percent_Identity=31.0679611650485, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=31.4655172413793, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17933730, Length=205, Percent_Identity=31.219512195122, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571670, Length=171, Percent_Identity=29.8245614035088, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI85725204, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737923, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864592, Length=198, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45549270, Length=195, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864598, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130115, Length=190, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864594, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24646251, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24654965, Length=195, Percent_Identity=31.2820512820513, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646249, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864596, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19922160, Length=204, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23177; Mature: 23177

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYTFTTPNGRKVSVMLEEVGLPYTVHVVDISSGDQHREEYLAINPNGKIPAIIDHDT
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCC
GLTIFESGAILIYLAEKTGKLLPSEPAARYAALQWLMWQMGGVGPMFGQLNHFKRFADEH
CEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
VPYAIDRYFRESIRLYRVLNRQLSRNLYVAGREYTIADVAIFPWVQIHAFQGIILEDFPA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCEEEEEECCEEECCCCH
VEVWFERLKARPAVQRGMQVPAP
HHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure
MIDLYTFTTPNGRKVSVMLEEVGLPYTVHVVDISSGDQHREEYLAINPNGKIPAIIDHDT
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCC
GLTIFESGAILIYLAEKTGKLLPSEPAARYAALQWLMWQMGGVGPMFGQLNHFKRFADEH
CEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
VPYAIDRYFRESIRLYRVLNRQLSRNLYVAGREYTIADVAIFPWVQIHAFQGIILEDFPA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCEEEEEECCEEECCCCH
VEVWFERLKARPAVQRGMQVPAP
HHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]