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The map label for this gene is moaE [H]

Identifier: 37523936

GI number: 37523936

Start: 4600898

End: 4601347

Strand: Direct

Name: moaE [H]

Synonym: glr4367

Alternate gene names: 37523936

Gene position: 4600898-4601347 (Clockwise)

Preceding gene: 37523935

Following gene: 37523938

Centisome position: 98.75

GC content: 64.67

Gene sequence:

>450_bases
GTGGGCGGCGAACACTTTTGTTTTACGGACAAACCGCTTTCGATCGAGCGCGCCTACACCCTGACGGCCGCTCCCGCCTC
GGGGGCGGTGGTGACGATGGTGGGCACCGTGCGCGCCAGCACCGGGGGGCGGGCGGTCGCTTTTCTTGATTACGAAGCGT
TTGAACCGATGGCCCTGGATGTCTTTGCGCAGATCGCCCGTCAGATCCGCGAGCGCTGGCCCGCCACCGGCAACATCGTC
ATCCACCACCGCCTGGGACGCCTCATGGTGGGCGAAGCGAGCGTGATCATCGCCGTGGGCAACGCCCACCGAGCCGACGC
CTTTGCCGCCTGCCAGTACGCCATCGACACCCTCAAGCTGGATGCTCCTATCTGGAAAAAAGAGCACTGGGCGGATGGGG
ACAGCGACTGGGTGGTGGGTCTGGCGGTTCTCACTGAACCGAGTACCTGA

Upstream 100 bases:

>100_bases
GTCCGCTACGGCCTCAATCGCCAGTTCGTCGCCCCCGACACCCCAGTGGCCGACGGCGACGAACTGGTGCTCATCCCGCC
GGTGAGCGGAGGGTAGGGCC

Downstream 100 bases:

>100_bases
AGCCGGTTTACGGGTTTGCCCGGCCCCGAAATTGGTCTACCAGCGCTTTGAATTCCTGCCATTCTTCAGGGTTCAAAAAG
CGCTCACCTCGCAGTTTGTC

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MGGEHFCFTDKPLSIERAYTLTAAPASGAVVTMVGTVRASTGGRAVAFLDYEAFEPMALDVFAQIARQIRERWPATGNIV
IHHRLGRLMVGEASVIIAVGNAHRADAFAACQYAIDTLKLDAPIWKKEHWADGDSDWVVGLAVLTEPST

Sequences:

>Translated_149_residues
MGGEHFCFTDKPLSIERAYTLTAAPASGAVVTMVGTVRASTGGRAVAFLDYEAFEPMALDVFAQIARQIRERWPATGNIV
IHHRLGRLMVGEASVIIAVGNAHRADAFAACQYAIDTLKLDAPIWKKEHWADGDSDWVVGLAVLTEPST
>Mature_148_residues
GGEHFCFTDKPLSIERAYTLTAAPASGAVVTMVGTVRASTGGRAVAFLDYEAFEPMALDVFAQIARQIRERWPATGNIVI
HHRLGRLMVGEASVIIAVGNAHRADAFAACQYAIDTLKLDAPIWKKEHWADGDSDWVVGLAVLTEPST

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=130, Percent_Identity=45.3846153846154, Blast_Score=114, Evalue=4e-26,
Organism=Escherichia coli, GI1787003, Length=129, Percent_Identity=38.7596899224806, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17509279, Length=135, Percent_Identity=37.037037037037, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356259, Length=135, Percent_Identity=40.7407407407407, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16098; Mature: 15966

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGEHFCFTDKPLSIERAYTLTAAPASGAVVTMVGTVRASTGGRAVAFLDYEAFEPMALD
CCCCEEEEECCCCCEEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEEEECCCCCCHHHH
VFAQIARQIRERWPATGNIVIHHRLGRLMVGEASVIIAVGNAHRADAFAACQYAIDTLKL
HHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHEEEE
DAPIWKKEHWADGDSDWVVGLAVLTEPST
CCCCCCCCCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
GGEHFCFTDKPLSIERAYTLTAAPASGAVVTMVGTVRASTGGRAVAFLDYEAFEPMALD
CCCEEEEECCCCCEEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEEEECCCCCCHHHH
VFAQIARQIRERWPATGNIVIHHRLGRLMVGEASVIIAVGNAHRADAFAACQYAIDTLKL
HHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHEEEE
DAPIWKKEHWADGDSDWVVGLAVLTEPST
CCCCCCCCCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]