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The map label for this gene is btuR [C]

Identifier: 37523889

GI number: 37523889

Start: 4551763

End: 4552944

Strand: Direct

Name: btuR [C]

Synonym: glr4320

Alternate gene names: 37523889

Gene position: 4551763-4552944 (Clockwise)

Preceding gene: 37523887

Following gene: 37523891

Centisome position: 97.7

GC content: 61.76

Gene sequence:

>1182_bases
GTGGTAGAGTGGGGCCGTTCAGCCAGGCGCAACACTTCTAGAGAGACACCCATGGCGGAGATTGGCATTCTCACAGCCCA
GGTCATTCCCGATCGCACCATTGGCCAGATCCACGTCTACGACGGGCTGGGCAAGGGTAAGTCCCAGGCGGCTTTGGGGG
TGGTGCTGCGTTCGATCGGTCTTGGGATCGCCGAAAAGCGCGACAACCGCGTGCTGCTTCTGCGTTTTCTCAAGGGTCCG
GGGCGCGAGTATTCCGAGGACGCCGCCATCGAGGCGCTCCGTCGTGCTTTCCCTCATCTGATTGATCAAGTCCGCACCGG
CCGGGCCGAATTTTTCGGCCCGGACCAGGTGATTCCGTTTGACAAAAAAGAAGCGCGCCGGGGTTGGGACATCGCGAAGG
GAGCGATTGCCTCGGGCTTCTACTCGGTGCTGGTGCTCGATGAACTCAACCCGGTGCTCGATCTGGGTCTGTTGCCGGTA
GCGGAGGTGGTGAGCGCCCTCTCCAACAAGCCCCAGGATCTGGAGGTAATCATTACCGGCCGCGGCGCCCCCAAAGAGAT
TCTCGAAGTGGCCAATTTGCACTCGGAGATGCGCGCCCACCGCCGTCCCGAGCACAACGGCAACGGCCGCGACTCGGGGA
TTGAAATTTATACCGGCGCCGGCAAGGGCAAATCGACCTCAGCTTTGGGCCGGGCCTTGCAGGCGATTGGCCAGGGCATT
TCCCGCGACCTGTCGCACCGGGTGCTCATCATGCAGTGGCTCAAGGGCGGCACAGGCTACACCGAAGACGCGGCCATCCG
CGCTTTGCACCAGAGCTATCCGCATCTTATCGACCACCACCGCTCCGGCCGCGACGCGATTGTCTGGCGCGGCAAACAGC
AGGAAATTGATTACGTCGAGGCCGAGCGCGGCTGGGAGATTGCCCAGGCGGCCATCGCCTCGGGGCTTTACAAGACGATC
ATTTTGGACGAACTGAATCCGACGGTGGATCTCGAACTATTGCCGGTCGAACCGATCGTCAAGGCGCTGCTGCGCAAGCC
CCGCGACACCGAGATCATCATCACCGGCCGCTGCTACAAGCCGCCCGCCTACTTCGAGCTTGCCACCATCCACTCCGAGA
TGGTCTGCCACAAGCACTACGCCGAGCAGGGCGTCGACCTCAAGCGAGGTGTCGATTTTTAA

Upstream 100 bases:

>100_bases
GCTGCCCCTGGGCTACATTGGGGAAGGCTGCGGCACGGTTTTTCCTTGAGACGCTAGATGTGGAGAAATTCAAAGCTGGG
ATACTAAATGTGCCCCAGGC

Downstream 100 bases:

>100_bases
AGTGTCCAGTGCATCGAGTACCGCCTTCCCCCGGTTCTTCACCCTTGCCAGGTGGTAGACCGGGGGATTTTTTTGGTTTG
GGTACTCGACATTATCAAGG

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MVEWGRSARRNTSRETPMAEIGILTAQVIPDRTIGQIHVYDGLGKGKSQAALGVVLRSIGLGIAEKRDNRVLLLRFLKGP
GREYSEDAAIEALRRAFPHLIDQVRTGRAEFFGPDQVIPFDKKEARRGWDIAKGAIASGFYSVLVLDELNPVLDLGLLPV
AEVVSALSNKPQDLEVIITGRGAPKEILEVANLHSEMRAHRRPEHNGNGRDSGIEIYTGAGKGKSTSALGRALQAIGQGI
SRDLSHRVLIMQWLKGGTGYTEDAAIRALHQSYPHLIDHHRSGRDAIVWRGKQQEIDYVEAERGWEIAQAAIASGLYKTI
ILDELNPTVDLELLPVEPIVKALLRKPRDTEIIITGRCYKPPAYFELATIHSEMVCHKHYAEQGVDLKRGVDF

Sequences:

>Translated_393_residues
MVEWGRSARRNTSRETPMAEIGILTAQVIPDRTIGQIHVYDGLGKGKSQAALGVVLRSIGLGIAEKRDNRVLLLRFLKGP
GREYSEDAAIEALRRAFPHLIDQVRTGRAEFFGPDQVIPFDKKEARRGWDIAKGAIASGFYSVLVLDELNPVLDLGLLPV
AEVVSALSNKPQDLEVIITGRGAPKEILEVANLHSEMRAHRRPEHNGNGRDSGIEIYTGAGKGKSTSALGRALQAIGQGI
SRDLSHRVLIMQWLKGGTGYTEDAAIRALHQSYPHLIDHHRSGRDAIVWRGKQQEIDYVEAERGWEIAQAAIASGLYKTI
ILDELNPTVDLELLPVEPIVKALLRKPRDTEIIITGRCYKPPAYFELATIHSEMVCHKHYAEQGVDLKRGVDF
>Mature_393_residues
MVEWGRSARRNTSRETPMAEIGILTAQVIPDRTIGQIHVYDGLGKGKSQAALGVVLRSIGLGIAEKRDNRVLLLRFLKGP
GREYSEDAAIEALRRAFPHLIDQVRTGRAEFFGPDQVIPFDKKEARRGWDIAKGAIASGFYSVLVLDELNPVLDLGLLPV
AEVVSALSNKPQDLEVIITGRGAPKEILEVANLHSEMRAHRRPEHNGNGRDSGIEIYTGAGKGKSTSALGRALQAIGQGI
SRDLSHRVLIMQWLKGGTGYTEDAAIRALHQSYPHLIDHHRSGRDAIVWRGKQQEIDYVEAERGWEIAQAAIASGLYKTI
ILDELNPTVDLELLPVEPIVKALLRKPRDTEIIITGRCYKPPAYFELATIHSEMVCHKHYAEQGVDLKRGVDF

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=181, Percent_Identity=30.939226519337, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 43482; Mature: 43482

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEWGRSARRNTSRETPMAEIGILTAQVIPDRTIGQIHVYDGLGKGKSQAALGVVLRSIG
CCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
LGIAEKRDNRVLLLRFLKGPGREYSEDAAIEALRRAFPHLIDQVRTGRAEFFGPDQVIPF
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCC
DKKEARRGWDIAKGAIASGFYSVLVLDELNPVLDLGLLPVAEVVSALSNKPQDLEVIITG
CHHHHHCCCHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
RGAPKEILEVANLHSEMRAHRRPEHNGNGRDSGIEIYTGAGKGKSTSALGRALQAIGQGI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
SRDLSHRVLIMQWLKGGTGYTEDAAIRALHQSYPHLIDHHRSGRDAIVWRGKQQEIDYVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCHHH
AERGWEIAQAAIASGLYKTIILDELNPTVDLELLPVEPIVKALLRKPRDTEIIITGRCYK
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCC
PPAYFELATIHSEMVCHKHYAEQGVDLKRGVDF
CCCCEEHHHHHHHHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MVEWGRSARRNTSRETPMAEIGILTAQVIPDRTIGQIHVYDGLGKGKSQAALGVVLRSIG
CCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
LGIAEKRDNRVLLLRFLKGPGREYSEDAAIEALRRAFPHLIDQVRTGRAEFFGPDQVIPF
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCC
DKKEARRGWDIAKGAIASGFYSVLVLDELNPVLDLGLLPVAEVVSALSNKPQDLEVIITG
CHHHHHCCCHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
RGAPKEILEVANLHSEMRAHRRPEHNGNGRDSGIEIYTGAGKGKSTSALGRALQAIGQGI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
SRDLSHRVLIMQWLKGGTGYTEDAAIRALHQSYPHLIDHHRSGRDAIVWRGKQQEIDYVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCHHH
AERGWEIAQAAIASGLYKTIILDELNPTVDLELLPVEPIVKALLRKPRDTEIIITGRCYK
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCC
PPAYFELATIHSEMVCHKHYAEQGVDLKRGVDF
CCCCEEHHHHHHHHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]