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The map label for this gene is bcsA [H]

Identifier: 37523798

GI number: 37523798

Start: 4442144

End: 4443622

Strand: Direct

Name: bcsA [H]

Synonym: glr4229

Alternate gene names: 37523798

Gene position: 4442144-4443622 (Clockwise)

Preceding gene: 37523797

Following gene: 37523799

Centisome position: 95.35

GC content: 66.13

Gene sequence:

>1479_bases
GTGCTCAACAGCCTGGCAGCCCTGTGGCTTTTTACCTACGGGATCAATGCCTACTGGCTGACTGCCCGGCGCGGGGCGCC
GCCGCCTGTGCCGCCTTCTCCTGGGCGGTGGCCGCTGGTGACGGTGCAGCTGCCGGTTTTCAATGAACTGTACGTCTGTC
GCCGCCTGCTCGCTGCGACCTGCGCCCTCGACTACCCGCGCGAGGCCCTGCACATCCAGGTGCTCGACGATTCCACCGAC
GAGACGGTCCAACTGCTGGCCGCCGCCATCGAGGAGCAACGGCGGCTCGGCTTCAGTATCGAACATTTGCATCGCAAAGA
GCGCCACGGCTTTAAAGCCGGCGCCCTGGCCGCCGCCACACCCCTAGCGAACGGTGAATACATCGCCATCTTCGATGCGG
ACTTTTTGCCGCCCCCGGACTGGTTGAAGCGCGCCCTGGTGCACTTTGCCGATGGGCGCGTCGGGCTGGTGCAGACGCGC
TGGGGACACACCAATCCGGGCTATTCGCTGTTGACCAGGTTGCAGGCGCTCGGTATCGACGGCCACTTCGCCGTCGAACA
GCAGGCGCGCTGCGCCAACGGCTACTACTTCAATTTCAACGGCACCGCCGGTGTGTGGCGCAAGCGGGCGATCGAGGCCG
GTGGCGGCTGGCAGGCCGACACCCTCGCAGAAGACCTCGACCTCAGCTACCGCAGCCAGTTGGCCGGTTGGAAAGCGGTA
TACGACGGGCGGATCGTCGCCCCGGCCGAGTTGCCGGTCTCGATGGCCGCCTACAAAATGCAGCAGTACCGTTGGGCCAA
AGGCAGCATCCAATGCGCCCGCAAATTGCTCGGCCGGGTGATGGACTGCGGGGGCAGCCCGATGCAGAAGTTGCAGGCGG
CGTTGCACCTGACCGGCTACGCGGTCCATCCGCTGATGGTCTGGATTGTGCTGTGTTCAGTGCCGCTGTTGACGGTCAGT
TGGGTGGGGCAGCACCCGCTCAGCCTGGTCTGGGGAACGCTGATGGTGCCTGCCACCTTCGGGCCGCCGACGCTCTACCT
GGCGGCCCGGCGCGATCTCGATCCGCGCGGTTGGCGCCGCTCACTCGCGGCGGTAGCGCTGCTTGCGGTTCTTGGGACCG
GGTTGTCGCTTTCGAATAGCCGCGCTGTACTCGCGGGCCTTTTTGACCGGGGAGGCGCTTTTCGGCGCACCCCCAAATTT
GCCGTGGTGGCCAGGGGCGATCGCTGGGAGCACAAGCGCTACCGGCTCCCCCTCGATTGGGGAAGTTTCGCGGAACTCGC
CCTGAGCCTCTACGCCGGTTGGGGAATACTCCTGGCTTTCCACGGGCGCGCCTGGGGTATGCTGCCGTTTTTGTTGCTCT
ACGTGCTCGGATACGCTTACGTGGGGGGCCTCGGACTGTGGCAGCATCTTCGCCCCACCCGGCAGAGCGACGGGACGCAG
GCCCTGGCCGCAAGCGCGCCCCAGACACGTCGGCTCTGA

Upstream 100 bases:

>100_bases
CACCAACCCCAGGTGGTGTACGTCGATGCTCAGAACCGCATCGTCTCGGTCCACAGGAGCGTCGAACACGCTGGTTGAGA
TCTGGGCCTTTGCGCTGTTG

Downstream 100 bases:

>100_bases
ACCGCGATTCCCATCGCAGCGTCCGCACCTGTAGATTCAATCGGAGAGATAACATGCGCTTTTTTGTCCTTCTGGCACTG
TCGGGCTTGCTGGCCGGTTC

Product: glucosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLNSLAALWLFTYGINAYWLTARRGAPPPVPPSPGRWPLVTVQLPVFNELYVCRRLLAATCALDYPREALHIQVLDDSTD
ETVQLLAAAIEEQRRLGFSIEHLHRKERHGFKAGALAAATPLANGEYIAIFDADFLPPPDWLKRALVHFADGRVGLVQTR
WGHTNPGYSLLTRLQALGIDGHFAVEQQARCANGYYFNFNGTAGVWRKRAIEAGGGWQADTLAEDLDLSYRSQLAGWKAV
YDGRIVAPAELPVSMAAYKMQQYRWAKGSIQCARKLLGRVMDCGGSPMQKLQAALHLTGYAVHPLMVWIVLCSVPLLTVS
WVGQHPLSLVWGTLMVPATFGPPTLYLAARRDLDPRGWRRSLAAVALLAVLGTGLSLSNSRAVLAGLFDRGGAFRRTPKF
AVVARGDRWEHKRYRLPLDWGSFAELALSLYAGWGILLAFHGRAWGMLPFLLLYVLGYAYVGGLGLWQHLRPTRQSDGTQ
ALAASAPQTRRL

Sequences:

>Translated_492_residues
MLNSLAALWLFTYGINAYWLTARRGAPPPVPPSPGRWPLVTVQLPVFNELYVCRRLLAATCALDYPREALHIQVLDDSTD
ETVQLLAAAIEEQRRLGFSIEHLHRKERHGFKAGALAAATPLANGEYIAIFDADFLPPPDWLKRALVHFADGRVGLVQTR
WGHTNPGYSLLTRLQALGIDGHFAVEQQARCANGYYFNFNGTAGVWRKRAIEAGGGWQADTLAEDLDLSYRSQLAGWKAV
YDGRIVAPAELPVSMAAYKMQQYRWAKGSIQCARKLLGRVMDCGGSPMQKLQAALHLTGYAVHPLMVWIVLCSVPLLTVS
WVGQHPLSLVWGTLMVPATFGPPTLYLAARRDLDPRGWRRSLAAVALLAVLGTGLSLSNSRAVLAGLFDRGGAFRRTPKF
AVVARGDRWEHKRYRLPLDWGSFAELALSLYAGWGILLAFHGRAWGMLPFLLLYVLGYAYVGGLGLWQHLRPTRQSDGTQ
ALAASAPQTRRL
>Mature_492_residues
MLNSLAALWLFTYGINAYWLTARRGAPPPVPPSPGRWPLVTVQLPVFNELYVCRRLLAATCALDYPREALHIQVLDDSTD
ETVQLLAAAIEEQRRLGFSIEHLHRKERHGFKAGALAAATPLANGEYIAIFDADFLPPPDWLKRALVHFADGRVGLVQTR
WGHTNPGYSLLTRLQALGIDGHFAVEQQARCANGYYFNFNGTAGVWRKRAIEAGGGWQADTLAEDLDLSYRSQLAGWKAV
YDGRIVAPAELPVSMAAYKMQQYRWAKGSIQCARKLLGRVMDCGGSPMQKLQAALHLTGYAVHPLMVWIVLCSVPLLTVS
WVGQHPLSLVWGTLMVPATFGPPTLYLAARRDLDPRGWRRSLAAVALLAVLGTGLSLSNSRAVLAGLFDRGGAFRRTPKF
AVVARGDRWEHKRYRLPLDWGSFAELALSLYAGWGILLAFHGRAWGMLPFLLLYVLGYAYVGGLGLWQHLRPTRQSDGTQ
ALAASAPQTRRL

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=255, Percent_Identity=27.4509803921569, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787259, Length=273, Percent_Identity=25.2747252747253, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR005150
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03552 Cellulose_synt; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 54402; Mature: 54402

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSLAALWLFTYGINAYWLTARRGAPPPVPPSPGRWPLVTVQLPVFNELYVCRRLLAAT
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
CALDYPREALHIQVLDDSTDETVQLLAAAIEEQRRLGFSIEHLHRKERHGFKAGALAAAT
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHC
PLANGEYIAIFDADFLPPPDWLKRALVHFADGRVGLVQTRWGHTNPGYSLLTRLQALGID
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
GHFAVEQQARCANGYYFNFNGTAGVWRKRAIEAGGGWQADTLAEDLDLSYRSQLAGWKAV
CCEEHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHCCCCCEE
YDGRIVAPAELPVSMAAYKMQQYRWAKGSIQCARKLLGRVMDCGGSPMQKLQAALHLTGY
ECCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
AVHPLMVWIVLCSVPLLTVSWVGQHPLSLVWGTLMVPATFGPPTLYLAARRDLDPRGWRR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHH
SLAAVALLAVLGTGLSLSNSRAVLAGLFDRGGAFRRTPKFAVVARGDRWEHKRYRLPLDW
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEECCCCC
GSFAELALSLYAGWGILLAFHGRAWGMLPFLLLYVLGYAYVGGLGLWQHLRPTRQSDGTQ
CHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALAASAPQTRRL
HHHCCCCHHCCC
>Mature Secondary Structure
MLNSLAALWLFTYGINAYWLTARRGAPPPVPPSPGRWPLVTVQLPVFNELYVCRRLLAAT
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
CALDYPREALHIQVLDDSTDETVQLLAAAIEEQRRLGFSIEHLHRKERHGFKAGALAAAT
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHC
PLANGEYIAIFDADFLPPPDWLKRALVHFADGRVGLVQTRWGHTNPGYSLLTRLQALGID
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
GHFAVEQQARCANGYYFNFNGTAGVWRKRAIEAGGGWQADTLAEDLDLSYRSQLAGWKAV
CCEEHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHCCCCCEE
YDGRIVAPAELPVSMAAYKMQQYRWAKGSIQCARKLLGRVMDCGGSPMQKLQAALHLTGY
ECCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
AVHPLMVWIVLCSVPLLTVSWVGQHPLSLVWGTLMVPATFGPPTLYLAARRDLDPRGWRR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHH
SLAAVALLAVLGTGLSLSNSRAVLAGLFDRGGAFRRTPKFAVVARGDRWEHKRYRLPLDW
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEECCCCC
GSFAELALSLYAGWGILLAFHGRAWGMLPFLLLYVLGYAYVGGLGLWQHLRPTRQSDGTQ
CHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALAASAPQTRRL
HHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]