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The map label for this gene is phoB [H]

Identifier: 37523782

GI number: 37523782

Start: 4411591

End: 4411977

Strand: Direct

Name: phoB [H]

Synonym: glr4213

Alternate gene names: 37523782

Gene position: 4411591-4411977 (Clockwise)

Preceding gene: 37523781

Following gene: 37523783

Centisome position: 94.69

GC content: 60.72

Gene sequence:

>387_bases
ATGAAGCGCATCCTGGTCATCGACGACGAGGCGGATATCCGCGAAGTGATTCAGCTGACTCTGGAATTGACCCGCGGTTG
GGAAATTGTTGCTGCCGAGTCGGGATCAGAAGGGATCGCCTTGGCGACAAGCCGCAATCCGGATGCCATCTTGCTCGATG
TGATGATGCCGGAGATGGACGGGGTGTCGACTTTTGCCGGGCTGCAGGCCGAAGCTGCCACCCGTTCGATCCCGGTGGTG
CTGCTCACCGCCAAAGTGCAGAGCGCCGACAGGCGTCGCTTCGCCGAACTGGGGGTGGCTGGGGTGATTGCCAAACCCTT
TGATCCGATGGGCCTCACCGATCAGCTCGAAGCGCTTTTGGGTTGGAATGCCCGACGCGAAGGCTAG

Upstream 100 bases:

>100_bases
CCCTGTTTTTTACCAAAAGCCGCATCCCGCCTGTCGAGTTCGAGCATCAGGTTTTAAGGTTGCTGGCGCGTATCGCCCGC
GAGCAGGCCGGGGAGGCCGG

Downstream 100 bases:

>100_bases
AGCAAGCTTCAGGTTTGCGGAGCCGATATGACTCATTGCGCCGCACGGCTTGCCCCAGGCGGGTTGCAGGCAGCCTTCTC
CGGTTTTTCACCATTGCTGC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKRILVIDDEADIREVIQLTLELTRGWEIVAAESGSEGIALATSRNPDAILLDVMMPEMDGVSTFAGLQAEAATRSIPVV
LLTAKVQSADRRRFAELGVAGVIAKPFDPMGLTDQLEALLGWNARREG

Sequences:

>Translated_128_residues
MKRILVIDDEADIREVIQLTLELTRGWEIVAAESGSEGIALATSRNPDAILLDVMMPEMDGVSTFAGLQAEAATRSIPVV
LLTAKVQSADRRRFAELGVAGVIAKPFDPMGLTDQLEALLGWNARREG
>Mature_128_residues
MKRILVIDDEADIREVIQLTLELTRGWEIVAAESGSEGIALATSRNPDAILLDVMMPEMDGVSTFAGLQAEAATRSIPVV
LLTAKVQSADRRRFAELGVAGVIAKPFDPMGLTDQLEALLGWNARREG

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=40.3361344537815, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=66, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13833; Mature: 13833

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILVIDDEADIREVIQLTLELTRGWEIVAAESGSEGIALATSRNPDAILLDVMMPEMD
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCC
GVSTFAGLQAEAATRSIPVVLLTAKVQSADRRRFAELGVAGVIAKPFDPMGLTDQLEALL
CCCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHH
GWNARREG
CCCCCCCC
>Mature Secondary Structure
MKRILVIDDEADIREVIQLTLELTRGWEIVAAESGSEGIALATSRNPDAILLDVMMPEMD
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCC
GVSTFAGLQAEAATRSIPVVLLTAKVQSADRRRFAELGVAGVIAKPFDPMGLTDQLEALL
CCCHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHH
GWNARREG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]