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The map label for this gene is bsaA [H]

Identifier: 37523612

GI number: 37523612

Start: 4240809

End: 4241291

Strand: Direct

Name: bsaA [H]

Synonym: glr4043

Alternate gene names: 37523612

Gene position: 4240809-4241291 (Clockwise)

Preceding gene: 37523611

Following gene: 37523616

Centisome position: 91.02

GC content: 58.18

Gene sequence:

>483_bases
GTGGCTACCGTCAGCGATATCACCGTCCAGACAGTAGATGGGCAGGCCCGTTCCCTTGGCAGATACAAAGGTCAGGTGCT
GCTTATCGTCAACGTCGCTTCCTACTGTGGCTACACGCCCCAGTACGCGGGCCTCGAAAAGCTCTACCGCCGCTATAAAG
ATGCCGGGTTGCGGGTACTGGCCTTTCCCTGCAACGACTTTGGAGGGCAGGAGCCGGGTTCCAACGCCGAGATTGCCGAG
TTTTGCAGCCGCTACGATGTCAGCTTCGAGCTGTTCGACAAGGTGGGTGCGCGCGGCTACTACAAGCATCCCCTTTACGT
CCGCCTGAGTGAAGCGGCTGAGCCTGCGGGGGAAGTGTCCTGGAATTTTGAAAAGTTTTTAATCGCTAAATCGGGGGAGA
TCGTGGGCCGCTACCGCAGCGGTATCGGCCCGGAAGATCCGCAACTGGTCGCCGATATCGAACGCGAACTGGCGAAAAGT
TAG

Upstream 100 bases:

>100_bases
ATCGTATGTAGTGCCAAAATGTGTGGCTTACTTGTAAATTCGGCCGAAGCGTTTGTTCGGTGGTAGCATCTGGAGGCTGT
AAGCGAAAGCGGAGATTTCA

Downstream 100 bases:

>100_bases
CCTATTTCTTGTTGCCTTTGCTGCCCTTAACTTTGCTGTCCTTGACCGCATCGCCGAACTTGCTGTTCAGGAAGCTGCGG
AACTTGTTGATCAAGTTGGG

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MATVSDITVQTVDGQARSLGRYKGQVLLIVNVASYCGYTPQYAGLEKLYRRYKDAGLRVLAFPCNDFGGQEPGSNAEIAE
FCSRYDVSFELFDKVGARGYYKHPLYVRLSEAAEPAGEVSWNFEKFLIAKSGEIVGRYRSGIGPEDPQLVADIERELAKS

Sequences:

>Translated_160_residues
MATVSDITVQTVDGQARSLGRYKGQVLLIVNVASYCGYTPQYAGLEKLYRRYKDAGLRVLAFPCNDFGGQEPGSNAEIAE
FCSRYDVSFELFDKVGARGYYKHPLYVRLSEAAEPAGEVSWNFEKFLIAKSGEIVGRYRSGIGPEDPQLVADIERELAKS
>Mature_159_residues
ATVSDITVQTVDGQARSLGRYKGQVLLIVNVASYCGYTPQYAGLEKLYRRYKDAGLRVLAFPCNDFGGQEPGSNAEIAEF
CSRYDVSFELFDKVGARGYYKHPLYVRLSEAAEPAGEVSWNFEKFLIAKSGEIVGRYRSGIGPEDPQLVADIERELAKS

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=162, Percent_Identity=41.9753086419753, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI90903240, Length=162, Percent_Identity=41.9753086419753, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI15618997, Length=154, Percent_Identity=40.9090909090909, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=41.2213740458015, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI192455698, Length=141, Percent_Identity=36.8794326241135, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI6006001, Length=162, Percent_Identity=32.7160493827161, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI4557629, Length=144, Percent_Identity=36.1111111111111, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI41406084, Length=153, Percent_Identity=37.2549019607843, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI33186887, Length=160, Percent_Identity=32.5, Blast_Score=81, Evalue=4e-16,
Organism=Homo sapiens, GI32967607, Length=161, Percent_Identity=31.6770186335404, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1788003, Length=180, Percent_Identity=38.3333333333333, Blast_Score=138, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=163, Percent_Identity=41.1042944785276, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71993584, Length=161, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=39.8773006134969, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=30.2197802197802, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193210707, Length=151, Percent_Identity=37.7483443708609, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=42.1052631578947, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=38.9473684210526, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=74, Percent_Identity=50, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=135, Percent_Identity=48.8888888888889, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=42.4050632911392, Blast_Score=126, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322826, Length=136, Percent_Identity=38.2352941176471, Blast_Score=108, Evalue=3e-25,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=40, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24656772, Length=163, Percent_Identity=38.0368098159509, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656767, Length=163, Percent_Identity=38.0368098159509, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=38.0368098159509, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17748; Mature: 17617

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVSDITVQTVDGQARSLGRYKGQVLLIVNVASYCGYTPQYAGLEKLYRRYKDAGLRVL
CCCCCCEEEEEECCHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHCCCCEEE
AFPCNDFGGQEPGSNAEIAEFCSRYDVSFELFDKVGARGYYKHPLYVRLSEAAEPAGEVS
EEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEECCCEEEEECCCCCCCCCCC
WNFEKFLIAKSGEIVGRYRSGIGPEDPQLVADIERELAKS
CCHHEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATVSDITVQTVDGQARSLGRYKGQVLLIVNVASYCGYTPQYAGLEKLYRRYKDAGLRVL
CCCCCEEEEEECCHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHCCCCEEE
AFPCNDFGGQEPGSNAEIAEFCSRYDVSFELFDKVGARGYYKHPLYVRLSEAAEPAGEVS
EEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEECCCEEEEECCCCCCCCCCC
WNFEKFLIAKSGEIVGRYRSGIGPEDPQLVADIERELAKS
CCHHEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]