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The map label for this gene is argJ

Identifier: 37523603

GI number: 37523603

Start: 4233010

End: 4234230

Strand: Direct

Name: argJ

Synonym: gvip544

Alternate gene names: 37523603

Gene position: 4233010-4234230 (Clockwise)

Preceding gene: 37523602

Following gene: 37523604

Centisome position: 90.86

GC content: 65.03

Gene sequence:

>1221_bases
ATGGCGGATTTCGAGTGGATCGATGGCGGGGTGACCGCAGCAAAGGGCTTTCGCGCGGGCGGCATCGCCAGCGGCATCAA
ACCGAGCGGCAAAACGGATCTGGCGCTCATCTATTCGGAGAACCCCTCGGCGGCGGCCGGGGTATACACCACCAACCTGG
TTCAAGCCGCCCCAGTGGCCTATAACCGCAATTTGCTGCAGCAGCGGGGCAAAGCCTGCGCCATCGTGGTCAATTCCGGC
AACGCCAACGCCGCCACCGGCAAAGCCGGCGAGGAGGCCGCCATCGAGACCGCCCAGGTCTTTGCCCGTGCGCTCGGCTT
CAGCGCCGATCAGGTGCTGGTGGCTTCTACGGGGGTGATCGGGGTGCCGCTGCCCATCGAAAAAATCCGCACCGCCGCCC
AGGCTCTGGTCGATGCAGCCACCGAGACCGGCTCCGATGCGGCGGCCGAAGCCATCCTCACCACCGACCTGGTGGCCAAA
TCCTGCGCGGTGCGCGCGCTCATCGGCGGCAAGACCGTGCACGTGGGCGGCATCGCCAAGGGTTCAGGGATGATCCACCC
GCAGATGGCGACGTTGCTGGCCTTCATCACCAGCGACTGCTCGGTGGATATCGACCTGTGGCGGCAGATCGTGGCCAGAG
CCACCGACCGCTCCTTCAACCAGATCACCGTCGACGGCGATACCAGCACCAACGACATGCTGCTGGCGCTGGCGAGCGGC
GAAGCGAAAAATCCCCGCATACTCGATGCGGCAAGTCCGGAAGCAGGCCTACTCGAACAGATGGTGAGCGCGGTGTGCGT
GGATCTGGCCAAAAAAGTCGTGCGCGACGGCGAGGGGGCGACCAAGCTCATCGAGGTGCAGGTGGCAGGCACCGGCGACG
ACGCCCAGGCGCGCAAGATCGCCCTCACCGTCGCCAGTTCTTCGCTGGTCAAATCGGCGATGTTCGGCAATGATCCCAAC
TGGGGCCGACTCGCGGCGGCAGCCGGACGGGCGGGGGTTGAATTTGACCCGGCGGCGCTTGCGGTGCGCCTTGGAGCCTT
TGCCTTGATGGAGGTGGGCCAGCCGCTTGCTTTTGATCGGGCTGCCGCGTCGGACTACTTGAAAGGCTCAGACACCGTCG
AAGTGCATCTGCAGGTCGGCCCCGGAACCGGAAACGGCATCGCCTGGGGCTGCGATCTCAGCTACGACTATGTGAAGATC
AACGCCGAGTACACCACCTGA

Upstream 100 bases:

>100_bases
CTTCGGCACGGTGGTCGCCACGATCTCGGTGGCGCGATAAATCCTTGCGGGTCTATCGGCGCTTTATAATCGCTGCGGAG
TGCTTGCGCGAGGGGCGGCG

Downstream 100 bases:

>100_bases
GAAGAGATACTTGTTGGAGGCAGACCTTTAGGGGCTAGAAGCCTTTAAATGCAAGGATGCGGTCGCTTGACAGCCTAGAT
TATAGTATGTATGCCTCAGA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MADFEWIDGGVTAAKGFRAGGIASGIKPSGKTDLALIYSENPSAAAGVYTTNLVQAAPVAYNRNLLQQRGKACAIVVNSG
NANAATGKAGEEAAIETAQVFARALGFSADQVLVASTGVIGVPLPIEKIRTAAQALVDAATETGSDAAAEAILTTDLVAK
SCAVRALIGGKTVHVGGIAKGSGMIHPQMATLLAFITSDCSVDIDLWRQIVARATDRSFNQITVDGDTSTNDMLLALASG
EAKNPRILDAASPEAGLLEQMVSAVCVDLAKKVVRDGEGATKLIEVQVAGTGDDAQARKIALTVASSSLVKSAMFGNDPN
WGRLAAAAGRAGVEFDPAALAVRLGAFALMEVGQPLAFDRAAASDYLKGSDTVEVHLQVGPGTGNGIAWGCDLSYDYVKI
NAEYTT

Sequences:

>Translated_406_residues
MADFEWIDGGVTAAKGFRAGGIASGIKPSGKTDLALIYSENPSAAAGVYTTNLVQAAPVAYNRNLLQQRGKACAIVVNSG
NANAATGKAGEEAAIETAQVFARALGFSADQVLVASTGVIGVPLPIEKIRTAAQALVDAATETGSDAAAEAILTTDLVAK
SCAVRALIGGKTVHVGGIAKGSGMIHPQMATLLAFITSDCSVDIDLWRQIVARATDRSFNQITVDGDTSTNDMLLALASG
EAKNPRILDAASPEAGLLEQMVSAVCVDLAKKVVRDGEGATKLIEVQVAGTGDDAQARKIALTVASSSLVKSAMFGNDPN
WGRLAAAAGRAGVEFDPAALAVRLGAFALMEVGQPLAFDRAAASDYLKGSDTVEVHLQVGPGTGNGIAWGCDLSYDYVKI
NAEYTT
>Mature_405_residues
ADFEWIDGGVTAAKGFRAGGIASGIKPSGKTDLALIYSENPSAAAGVYTTNLVQAAPVAYNRNLLQQRGKACAIVVNSGN
ANAATGKAGEEAAIETAQVFARALGFSADQVLVASTGVIGVPLPIEKIRTAAQALVDAATETGSDAAAEAILTTDLVAKS
CAVRALIGGKTVHVGGIAKGSGMIHPQMATLLAFITSDCSVDIDLWRQIVARATDRSFNQITVDGDTSTNDMLLALASGE
AKNPRILDAASPEAGLLEQMVSAVCVDLAKKVVRDGEGATKLIEVQVAGTGDDAQARKIALTVASSSLVKSAMFGNDPNW
GRLAAAAGRAGVEFDPAALAVRLGAFALMEVGQPLAFDRAAASDYLKGSDTVEVHLQVGPGTGNGIAWGCDLSYDYVKIN
AEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=38.6473429951691, Blast_Score=222, Evalue=7e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_GLOVI (Q7NE46)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926980.1
- ProteinModelPortal:   Q7NE46
- SMR:   Q7NE46
- MEROPS:   T05.001
- GeneID:   2602437
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.4034
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   GVIO251221:GLR4034-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 41584; Mature: 41453

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFEWIDGGVTAAKGFRAGGIASGIKPSGKTDLALIYSENPSAAAGVYTTNLVQAAPVA
CCCCEEECCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHCCCH
YNRNLLQQRGKACAIVVNSGNANAATGKAGEEAAIETAQVFARALGFSADQVLVASTGVI
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEE
GVPLPIEKIRTAAQALVDAATETGSDAAAEAILTTDLVAKSCAVRALIGGKTVHVGGIAK
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCEEC
GSGMIHPQMATLLAFITSDCSVDIDLWRQIVARATDRSFNQITVDGDTSTNDMLLALASG
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECC
EAKNPRILDAASPEAGLLEQMVSAVCVDLAKKVVRDGEGATKLIEVQVAGTGDDAQARKI
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEE
ALTVASSSLVKSAMFGNDPNWGRLAAAAGRAGVEFDPAALAVRLGAFALMEVGQPLAFDR
EEEECHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
AAASDYLKGSDTVEVHLQVGPGTGNGIAWGCDLSYDYVKINAEYTT
HHHHHHCCCCCEEEEEEEECCCCCCCEEEEECCCEEEEEEEEEECC
>Mature Secondary Structure 
ADFEWIDGGVTAAKGFRAGGIASGIKPSGKTDLALIYSENPSAAAGVYTTNLVQAAPVA
CCCEEECCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHCCCH
YNRNLLQQRGKACAIVVNSGNANAATGKAGEEAAIETAQVFARALGFSADQVLVASTGVI
HHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEE
GVPLPIEKIRTAAQALVDAATETGSDAAAEAILTTDLVAKSCAVRALIGGKTVHVGGIAK
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCEEC
GSGMIHPQMATLLAFITSDCSVDIDLWRQIVARATDRSFNQITVDGDTSTNDMLLALASG
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECC
EAKNPRILDAASPEAGLLEQMVSAVCVDLAKKVVRDGEGATKLIEVQVAGTGDDAQARKI
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEE
ALTVASSSLVKSAMFGNDPNWGRLAAAAGRAGVEFDPAALAVRLGAFALMEVGQPLAFDR
EEEECHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
AAASDYLKGSDTVEVHLQVGPGTGNGIAWGCDLSYDYVKINAEYTT
HHHHHHCCCCCEEEEEEEECCCCCCCEEEEECCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292