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The map label for this gene is argC

Identifier: 37523579

GI number: 37523579

Start: 4212680

End: 4213732

Strand: Direct

Name: argC

Synonym: gvip541

Alternate gene names: 37523579

Gene position: 4212680-4213732 (Clockwise)

Preceding gene: 37523577

Following gene: 37523581

Centisome position: 90.42

GC content: 64.67

Gene sequence:

>1053_bases
ATGGCCGAAAAATTGCGTGTCGGGATCGTGGGCGCCTCCGGGTACGGTGGGGTACAGCTGGTGCGCCTGCTACTGGATCA
CCCGCGCGTTGAGATCGCTTATTTGGGGGCGAACCAGAACGCCGGCACGCCCTTTGGTGAACTGTATCCGCAGTTGGCGC
ACCGCATCGATCGCGTGTGCGAGGCGGTCGAACTGGATCGAATCGTCGAGGCGTGCTCGGTGGTGTTTCTGGCCACCCCC
AACGGCATCGCCCACACCCTGGCGCCGGGGCTGCTCGCCGGTGGCTTGCGGGTGTTCGATCTCTCGGCGGATTACCGGTT
TGTCAATCTCGAAACCTATCAGTCCTGGTACGGCGGCGATCGCCACGACGCGGCGGTGGCCCGCGAGGCGGTCTACGGTC
TGCCGGAACTGTACCGCGAGCGCATCCGCACCGCCCGGCTGGTGGGCTGCCCGGGATGTTACCCGACCGCTTCGTTGCTG
GCTGCCGCCCCCCTGCTCAAGCAAGGGCTGATCGATCCGCGCAGCTTGATTATCGACGCCAAATCCGGTGTCTCCGGGGC
CGGGCGCGCCCTCAAGACCGGTTCGCTCTTTGCCGAGGCCGACAGCAGCGTGGCGGCCTACAGCGTCGCGCGCCACCGCC
ATATCCCGGAGATCGAGCAAGTTTGCTCGGATCTGGCCGGTATGCGCGTGCAGGTGCAGTTCACCCCCCATTTGATCCCG
ATGGCGCGAGGAATGCTCGTGACGCTCTATGCCCAATTGCGCGATCCGGGGCTGGTGAGCGAAGACATGCTCACTATCTA
CGAAGCGTTCTACCGCCAGGCGCCGGCCGTGCGTGTACTGGGTAGCGGCATCTATCCACAGACCAAGTGGGCAAGCGGCA
CGAACACCTGCTTTATCGGCCTGGAAGTCGACCAGCGCACCGAGCGGGTAGTGGTGCTCTCTGCCCTCGACAATCTGGTG
AAGGGCCAGTCCGGGCAGGCGATCCAGGCGATGAATCTTACCCAGGGTTGGGAGGAGATGCTGGGGCTGCCCGCCATCGG
GTTTTACCCCTGA

Upstream 100 bases:

>100_bases
TTTCGGGTGGGCCGGTGTAGTGGGCTTGACCGGCAGCGGTCGCGAAATCGAGCGCAGGCATTACACTGATGGCCGGACAA
CAGCTTCCGGGCGGGTATCT

Downstream 100 bases:

>100_bases
TGCCCAATGCCCGGCGCGCAAGCGCCGGGCATTGGGCATCACAGAGCTTGCAGATCAGGCGCTGACCAGCCGATCGAGGG
CGCGCTGCACCCACTGCATA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MAEKLRVGIVGASGYGGVQLVRLLLDHPRVEIAYLGANQNAGTPFGELYPQLAHRIDRVCEAVELDRIVEACSVVFLATP
NGIAHTLAPGLLAGGLRVFDLSADYRFVNLETYQSWYGGDRHDAAVAREAVYGLPELYRERIRTARLVGCPGCYPTASLL
AAAPLLKQGLIDPRSLIIDAKSGVSGAGRALKTGSLFAEADSSVAAYSVARHRHIPEIEQVCSDLAGMRVQVQFTPHLIP
MARGMLVTLYAQLRDPGLVSEDMLTIYEAFYRQAPAVRVLGSGIYPQTKWASGTNTCFIGLEVDQRTERVVVLSALDNLV
KGQSGQAIQAMNLTQGWEEMLGLPAIGFYP

Sequences:

>Translated_350_residues
MAEKLRVGIVGASGYGGVQLVRLLLDHPRVEIAYLGANQNAGTPFGELYPQLAHRIDRVCEAVELDRIVEACSVVFLATP
NGIAHTLAPGLLAGGLRVFDLSADYRFVNLETYQSWYGGDRHDAAVAREAVYGLPELYRERIRTARLVGCPGCYPTASLL
AAAPLLKQGLIDPRSLIIDAKSGVSGAGRALKTGSLFAEADSSVAAYSVARHRHIPEIEQVCSDLAGMRVQVQFTPHLIP
MARGMLVTLYAQLRDPGLVSEDMLTIYEAFYRQAPAVRVLGSGIYPQTKWASGTNTCFIGLEVDQRTERVVVLSALDNLV
KGQSGQAIQAMNLTQGWEEMLGLPAIGFYP
>Mature_349_residues
AEKLRVGIVGASGYGGVQLVRLLLDHPRVEIAYLGANQNAGTPFGELYPQLAHRIDRVCEAVELDRIVEACSVVFLATPN
GIAHTLAPGLLAGGLRVFDLSADYRFVNLETYQSWYGGDRHDAAVAREAVYGLPELYRERIRTARLVGCPGCYPTASLLA
AAPLLKQGLIDPRSLIIDAKSGVSGAGRALKTGSLFAEADSSVAAYSVARHRHIPEIEQVCSDLAGMRVQVQFTPHLIPM
ARGMLVTLYAQLRDPGLVSEDMLTIYEAFYRQAPAVRVLGSGIYPQTKWASGTNTCFIGLEVDQRTERVVVLSALDNLVK
GQSGQAIQAMNLTQGWEEMLGLPAIGFYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=35.1744186046512, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=347, Percent_Identity=29.3948126801153, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_GLOVI (Q7NE70)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926956.1
- ProteinModelPortal:   Q7NE70
- SMR:   Q7NE70
- GeneID:   2602413
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.4010
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   GVIO251221:GLR4010-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37885; Mature: 37754

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKLRVGIVGASGYGGVQLVRLLLDHPRVEIAYLGANQNAGTPFGELYPQLAHRIDRVC
CCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
EAVELDRIVEACSVVFLATPNGIAHTLAPGLLAGGLRVFDLSADYRFVNLETYQSWYGGD
HHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCEEEEEECCCEEEEEEEHHHHHCCCC
RHDAAVAREAVYGLPELYRERIRTARLVGCPGCYPTASLLAAAPLLKQGLIDPRSLIIDA
CHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEC
KSGVSGAGRALKTGSLFAEADSSVAAYSVARHRHIPEIEQVCSDLAGMRVQVQFTPHLIP
CCCCCCCCCCEECCCHHECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCHHH
MARGMLVTLYAQLRDPGLVSEDMLTIYEAFYRQAPAVRVLGSGIYPQTKWASGTNTCFIG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEE
LEVDQRTERVVVLSALDNLVKGQSGQAIQAMNLTQGWEEMLGLPAIGFYP
EEECCCCCCEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AEKLRVGIVGASGYGGVQLVRLLLDHPRVEIAYLGANQNAGTPFGELYPQLAHRIDRVC
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
EAVELDRIVEACSVVFLATPNGIAHTLAPGLLAGGLRVFDLSADYRFVNLETYQSWYGGD
HHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCEEEEEECCCEEEEEEEHHHHHCCCC
RHDAAVAREAVYGLPELYRERIRTARLVGCPGCYPTASLLAAAPLLKQGLIDPRSLIIDA
CHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEC
KSGVSGAGRALKTGSLFAEADSSVAAYSVARHRHIPEIEQVCSDLAGMRVQVQFTPHLIP
CCCCCCCCCCEECCCHHECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCHHH
MARGMLVTLYAQLRDPGLVSEDMLTIYEAFYRQAPAVRVLGSGIYPQTKWASGTNTCFIG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEE
LEVDQRTERVVVLSALDNLVKGQSGQAIQAMNLTQGWEEMLGLPAIGFYP
EEECCCCCCEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292