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The map label for this gene is acpS

Identifier: 37523577

GI number: 37523577

Start: 4211704

End: 4212102

Strand: Direct

Name: acpS

Synonym: glr4008

Alternate gene names: 37523577

Gene position: 4211704-4212102 (Clockwise)

Preceding gene: 37523576

Following gene: 37523579

Centisome position: 90.4

GC content: 63.66

Gene sequence:

>399_bases
ATGGCCGGCCAGACGTTTTTGCACCGCATCGGCACCGATCTGGTGCACATTCCCCGCATCGAGGGAATGCTGGAGCGCTA
CGGCAAACAGTTTCTTAATCGTGTCTACACCGAAGGCGAACAGCACTACTGTCTGGCATCGAAGCCGCACCGGGCCAACC
GGCTGGCGGGGCGCTGGGCGGCCAAGGAGGCGGTGACCAAGGCCCTGGGTACGGGCTGGCGGGGAGTGGGCTACCGCGAC
ATCGAAGTGGTGCGGCTCGCCTCGGGAGAGCCGACCATCTGTTTAAACGGGCGAGCGGTTCTCCTGGTGGAGCGCTTCGG
TCGGCTCGATTGGCAGGTCAGTTTCAGCCACGACCGCGAGTACGCCGTCGCCACCGTCTCGGTGATCGGCTTTTTTTAG

Upstream 100 bases:

>100_bases
GTTAAGCTGTTAGAAACTGTGGGATTCGGATGAAGTTCCCGGTGACAGTTCACAGAATAATCGCCGCACAGCACAGAGCA
ATCCATCAAATATGAGTAAC

Downstream 100 bases:

>100_bases
AGGCCGAGGCCGTCGATCATGCTGCGCTCCAGCCACAACAGCAAGAAAAAGGCCCCCGAGAGCATCAGGTGGCGGCCGGT
CCAGGCGTAGGCGTGCTCCT

Product: acyl-carrier protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWAAKEAVTKALGTGWRGVGYRD
IEVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDREYAVATVSVIGFF

Sequences:

>Translated_132_residues
MAGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWAAKEAVTKALGTGWRGVGYRD
IEVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDREYAVATVSVIGFF
>Mature_131_residues
AGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWAAKEAVTKALGTGWRGVGYRDI
EVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDREYAVATVSVIGFF

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=121, Percent_Identity=38.0165289256198, Blast_Score=73, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325025, Length=96, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_GLOVI (Q7NE72)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926954.1
- ProteinModelPortal:   Q7NE72
- SMR:   Q7NE72
- GeneID:   2602411
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr4008
- NMPDR:   fig|251221.1.peg.4008
- HOGENOM:   HBG734479
- OMA:   HIGTDII
- BioCyc:   GVIO251221:GLR4008-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14919; Mature: 14788

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWA
CCCHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AKEAVTKALGTGWRGVGYRDIEVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDRE
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEEECCCCCEEEEECCCCCC
YAVATVSVIGFF
HHHEEEEEEECC
>Mature Secondary Structure 
AGQTFLHRIGTDLVHIPRIEGMLERYGKQFLNRVYTEGEQHYCLASKPHRANRLAGRWA
CCHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AKEAVTKALGTGWRGVGYRDIEVVRLASGEPTICLNGRAVLLVERFGRLDWQVSFSHDRE
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEEECCCCCEEEEECCCCCC
YAVATVSVIGFF
HHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292