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The map label for this gene is recQ [H]

Identifier: 37523549

GI number: 37523549

Start: 4182087

End: 4183529

Strand: Direct

Name: recQ [H]

Synonym: gvip539

Alternate gene names: 37523549

Gene position: 4182087-4183529 (Clockwise)

Preceding gene: 37523544

Following gene: 37523554

Centisome position: 89.76

GC content: 69.58

Gene sequence:

>1443_bases
GTGCCAGACTGTGCGGCGGCGACTTGCCCGGGGGGACCGCCCCGGGGGCAACCGGCGCTATCCCCTGGGGCGAAACTCAT
CGCCATGCACGACGCCCGCCAAGTCCTGCAAAAACTCTGGGGCTACGCCGACTTTCGCCCCCAACAGCGGCCCATCGTCG
AGGCGGTGGCTGGCGGCCGGGATGTGCTTGCGGTGCTGCCCACCGGCGGCGGCAAGAGTGTCGCCTTTCAAGTGCCGGCG
CTGCTGAGGTCGGGTACGACGCTGGTGGTGACGCCGCTGGTGGCGCTTATGGAAGATCAAGTGGCGCGGTTGCGCTCGCT
CAAGGTGGCCGCCGCCTGCCTGCACGGCGAGCAATCGGCGGCGGTGCGCTCCGAGAGCCTGGCGGGCATCGAGACCGGCC
GCTGGGCCTTGTTGTACCTCTCGCCCGAGACGCTCCTCAGTCCGCCGACCTGGGCCAGGCTGCAAGGGTGCCCGATTGCC
CGGATGGTGCTCGATGAAGCCCACTGCCTGACCGGTTGGGGCAGCAGCTTTCGCCCCGACTACCACCGCCTCGGGGCGGC
GCGGCGCGCCCTCGGCCATCCGCCTCTGTGCGCCTTTACCGCCACCGCCGCCCCCGCCGACCGCGCCCGCATCGAACGCT
GGCTGGGCCTGGTGGACCCGGTGCGGCTGGTGATCGCACCCTACCGGCCAAACCTGGCCATCCGGGTGCGCTGGATGTAC
ACCACCCGCCAGCGCTGCGGTGCGGTCGGCGCTTTTTTGGCTTCCAGACCCGATACCTCGGGTCTGGTTTACCTGCGCAC
CCGCGCGGGCACCGAGAAGCTGGCCTTCGAACTGGCAAAAGCAGGTTACCGGACAACCCATTACCACGCCGGCCTGGGAG
CCGCCGCACGCCGCAGTGCCGAGCGCGACTGGCTTGCGGGCCGTCTGCAGTTTCTGGTGGCCACCAACGCCTTCGGCATG
GGGGTGGACGCCCCGCACGTGCGCTGGGTGATCCATGCCCACACCCCGCCCAGCCTCGAAGAGTACCTGCAGGAAATCGG
CCGCGCCGGGCGCGACGGTGAAGCGGCGACGGCCCTGCTGCTTGCGAGCGAACCAACCGGCTGGCTCGATCCGACCGACC
GGCTGCTGCATCGTCACTTTGCTGCGAATCGCCGCGAGCAGTGGCAGGCCGCCGAAAAAGCCCTCGCCCGCCTGCCCGCA
GAAGGCGAGTACCGCCCCGAATTGGCCCTCAGCCTTGCTTTGCTGCACGAGCGGGGCCGGTTGGTGTGGAAGACACCCTT
TGATTACCGCCTGGTCGAGACCCCTCCCACCCGGCCGCCTGAAATGGGTGCGGGCGTGCAGGATTTTGTGCGCACCTGCC
GCTGCCGCTGGCAATTTTTGATGGCGGCCTTCGGCGAAGCCGCGAGTCCGCCCTGCGGTCGCTGCGACCGCTGCACAGGT
TAG

Upstream 100 bases:

>100_bases
ATCCAGCGCAAATACCTGTTTGCGTTCAAAAAGCACGGGGGCGGAGGCGACCATGGCACAGCGGCAGGTTTGCACCTTAT
TCTAGAGCCTCGATTTGCAG

Downstream 100 bases:

>100_bases
ATGTCGGGGGTGCTTAGACCTGGCACCTGACACCATGTCCACATGTCAGGCTTCCAGTTTTGGTCCTGAATACTGCTGTT
GCAGCGGACGGATGCGGGTG

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MPDCAAATCPGGPPRGQPALSPGAKLIAMHDARQVLQKLWGYADFRPQQRPIVEAVAGGRDVLAVLPTGGGKSVAFQVPA
LLRSGTTLVVTPLVALMEDQVARLRSLKVAAACLHGEQSAAVRSESLAGIETGRWALLYLSPETLLSPPTWARLQGCPIA
RMVLDEAHCLTGWGSSFRPDYHRLGAARRALGHPPLCAFTATAAPADRARIERWLGLVDPVRLVIAPYRPNLAIRVRWMY
TTRQRCGAVGAFLASRPDTSGLVYLRTRAGTEKLAFELAKAGYRTTHYHAGLGAAARRSAERDWLAGRLQFLVATNAFGM
GVDAPHVRWVIHAHTPPSLEEYLQEIGRAGRDGEAATALLLASEPTGWLDPTDRLLHRHFAANRREQWQAAEKALARLPA
EGEYRPELALSLALLHERGRLVWKTPFDYRLVETPPTRPPEMGAGVQDFVRTCRCRWQFLMAAFGEAASPPCGRCDRCTG

Sequences:

>Translated_480_residues
MPDCAAATCPGGPPRGQPALSPGAKLIAMHDARQVLQKLWGYADFRPQQRPIVEAVAGGRDVLAVLPTGGGKSVAFQVPA
LLRSGTTLVVTPLVALMEDQVARLRSLKVAAACLHGEQSAAVRSESLAGIETGRWALLYLSPETLLSPPTWARLQGCPIA
RMVLDEAHCLTGWGSSFRPDYHRLGAARRALGHPPLCAFTATAAPADRARIERWLGLVDPVRLVIAPYRPNLAIRVRWMY
TTRQRCGAVGAFLASRPDTSGLVYLRTRAGTEKLAFELAKAGYRTTHYHAGLGAAARRSAERDWLAGRLQFLVATNAFGM
GVDAPHVRWVIHAHTPPSLEEYLQEIGRAGRDGEAATALLLASEPTGWLDPTDRLLHRHFAANRREQWQAAEKALARLPA
EGEYRPELALSLALLHERGRLVWKTPFDYRLVETPPTRPPEMGAGVQDFVRTCRCRWQFLMAAFGEAASPPCGRCDRCTG
>Mature_479_residues
PDCAAATCPGGPPRGQPALSPGAKLIAMHDARQVLQKLWGYADFRPQQRPIVEAVAGGRDVLAVLPTGGGKSVAFQVPAL
LRSGTTLVVTPLVALMEDQVARLRSLKVAAACLHGEQSAAVRSESLAGIETGRWALLYLSPETLLSPPTWARLQGCPIAR
MVLDEAHCLTGWGSSFRPDYHRLGAARRALGHPPLCAFTATAAPADRARIERWLGLVDPVRLVIAPYRPNLAIRVRWMYT
TRQRCGAVGAFLASRPDTSGLVYLRTRAGTEKLAFELAKAGYRTTHYHAGLGAAARRSAERDWLAGRLQFLVATNAFGMG
VDAPHVRWVIHAHTPPSLEEYLQEIGRAGRDGEAATALLLASEPTGWLDPTDRLLHRHFAANRREQWQAAEKALARLPAE
GEYRPELALSLALLHERGRLVWKTPFDYRLVETPPTRPPEMGAGVQDFVRTCRCRWQFLMAAFGEAASPPCGRCDRCTG

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI51242943, Length=340, Percent_Identity=39.7058823529412, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI51242947, Length=340, Percent_Identity=39.7058823529412, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI148612816, Length=339, Percent_Identity=39.8230088495575, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI14591902, Length=340, Percent_Identity=34.1176470588235, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI14591904, Length=340, Percent_Identity=34.1176470588235, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4557365, Length=336, Percent_Identity=35.1190476190476, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI110735439, Length=463, Percent_Identity=30.2375809935205, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI169218196, Length=463, Percent_Identity=30.2375809935205, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI284005309, Length=393, Percent_Identity=35.6234096692112, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI224593278, Length=341, Percent_Identity=23.1671554252199, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=449, Percent_Identity=36.5256124721604, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI87082221, Length=339, Percent_Identity=27.4336283185841, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787016, Length=369, Percent_Identity=26.0162601626016, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987997, Length=339, Percent_Identity=36.283185840708, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71987993, Length=339, Percent_Identity=36.283185840708, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI25145561, Length=339, Percent_Identity=35.1032448377581, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI32564293, Length=335, Percent_Identity=35.8208955223881, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17552866, Length=364, Percent_Identity=33.7912087912088, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71999646, Length=391, Percent_Identity=25.5754475703325, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71999644, Length=391, Percent_Identity=25.5754475703325, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17510559, Length=405, Percent_Identity=25.679012345679, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323844, Length=329, Percent_Identity=36.4741641337386, Blast_Score=216, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6324778, Length=351, Percent_Identity=24.7863247863248, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646066, Length=335, Percent_Identity=38.2089552238806, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24664226, Length=349, Percent_Identity=35.243553008596, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI62472181, Length=349, Percent_Identity=35.243553008596, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24664230, Length=349, Percent_Identity=35.243553008596, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI21358123, Length=382, Percent_Identity=32.7225130890052, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28575014, Length=366, Percent_Identity=23.7704918032787, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355075, Length=323, Percent_Identity=21.9814241486068, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52407; Mature: 52276

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDCAAATCPGGPPRGQPALSPGAKLIAMHDARQVLQKLWGYADFRPQQRPIVEAVAGGR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
DVLAVLPTGGGKSVAFQVPALLRSGTTLVVTPLVALMEDQVARLRSLKVAAACLHGEQSA
EEEEEEECCCCCEEEEECHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AVRSESLAGIETGRWALLYLSPETLLSPPTWARLQGCPIARMVLDEAHCLTGWGSSFRPD
HHHHHHHCCCCCCCEEEEEECHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCH
YHRLGAARRALGHPPLCAFTATAAPADRARIERWLGLVDPVRLVIAPYRPNLAIRVRWMY
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEE
TTRQRCGAVGAFLASRPDTSGLVYLRTRAGTEKLAFELAKAGYRTTHYHAGLGAAARRSA
ECHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCHHHHHCC
ERDWLAGRLQFLVATNAFGMGVDAPHVRWVIHAHTPPSLEEYLQEIGRAGRDGEAATALL
HHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEE
LASEPTGWLDPTDRLLHRHFAANRREQWQAAEKALARLPAEGEYRPELALSLALLHERGR
EECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
LVWKTPFDYRLVETPPTRPPEMGAGVQDFVRTCRCRWQFLMAAFGEAASPPCGRCDRCTG
EEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDCAAATCPGGPPRGQPALSPGAKLIAMHDARQVLQKLWGYADFRPQQRPIVEAVAGGR
CCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
DVLAVLPTGGGKSVAFQVPALLRSGTTLVVTPLVALMEDQVARLRSLKVAAACLHGEQSA
EEEEEEECCCCCEEEEECHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AVRSESLAGIETGRWALLYLSPETLLSPPTWARLQGCPIARMVLDEAHCLTGWGSSFRPD
HHHHHHHCCCCCCCEEEEEECHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCH
YHRLGAARRALGHPPLCAFTATAAPADRARIERWLGLVDPVRLVIAPYRPNLAIRVRWMY
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEE
TTRQRCGAVGAFLASRPDTSGLVYLRTRAGTEKLAFELAKAGYRTTHYHAGLGAAARRSA
ECHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCHHHHHCC
ERDWLAGRLQFLVATNAFGMGVDAPHVRWVIHAHTPPSLEEYLQEIGRAGRDGEAATALL
HHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEE
LASEPTGWLDPTDRLLHRHFAANRREQWQAAEKALARLPAEGEYRPELALSLALLHERGR
EECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
LVWKTPFDYRLVETPPTRPPEMGAGVQDFVRTCRCRWQFLMAAFGEAASPPCGRCDRCTG
EEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]