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The map label for this gene is fhuA [H]

Identifier: 37523545

GI number: 37523545

Start: 4177289

End: 4179526

Strand: Reverse

Name: fhuA [H]

Synonym: gll3976

Alternate gene names: 37523545

Gene position: 4179526-4177289 (Counterclockwise)

Preceding gene: 37523546

Following gene: 37523543

Centisome position: 89.71

GC content: 62.29

Gene sequence:

>2238_bases
GTGGTTGGCGTGGGCAACAAGGCGCACTCCGGGCGTGCCGGACGATTTGTCCTGGCCACATTGTCGGGCGTTATTGCTCA
AGCTTCGCAAGTGGCTGCAATCCCTACTGCCACTCAAAGCGAGCAGACCATTCCACGCCTGGCAGATCTAGAACCGATGC
AAACCGGGGCGCAGGGGTTGTTCGAAAGCCCCGTCGCTCAGGCGGAACCGGGCACCCAAAAGCCCCCGACCAGCCCGGAA
GATCTCGACGAAGTGACGGTGACCGGCACGCGCAGCTACCGGCGCTCGCGCTCTTCGACGGCCACCAAGACCGATACGGC
CATCCTGGATGTTCCCCAATCGATCCAGGTGATCCCCCGGCAGGTGCTCGAAGACCAGCGCATCGTCCGCGCCGGCGACG
CGCTGCAAAACGTCAGCGGCATCGTCAATCTAGGCAGCTACTCCGGCTATTCCGACTCCTTGCTTATTCGCGGCTTTGAG
GCGGCCGGCTTCGACGGATCTTTCTTCCGCGACGGTGTGCCCTACTTTCAGTTCGATTACGTCGAGACCGCCGACCTGGA
GCGCATCGAGGTGCTCAAAGGGCCGGCCTCGGTGCTGTTCGGCCAGGGCCAGCCGGGCGGGATCGTCAATCTGGTGAGCA
AACAGCCGCAGGCCAAACCCTACTATTCCGCTGCGCTCACCGCCGGCTCCTACAGCGACTACCGGGGACAGCTCGACCTG
TCCGGACCGCTCAACGCCGGGGGCACACTGCAGTATCGGCTCAACGCTTTTTACCAGAATGCCCGCAGCTTCCGCGACTT
TGTGCGCAACGACCGCAGCGTCCTCACCCCGGCCCTCACCTGGCAAATCAGCCCCCAGACGGCCCTGCGCTTCGACAGCT
ACTTCATCAACGAAGCGCGCACGATGGACGACGGCATCCCGGTGATTGGCCGCTCGGTGGCGAATGTGCCCATCGGTCGG
TTTCTGCACGAACCTTTCAGCAACTACCGCAAAGACGAGTACGGTCTGGGCTACAGCCTGGATCACCGCTTCAGCGAGAA
CTGGTCGCTCAGGCACACGGCGCGCTACCAGAACGTGAGCCCGGAGCGGTACTATCCGTTTTCGCTGGAATTGAACGAGC
AGACCGGAGAACTGTCGCGCCTCGCTTACTGGGCGGCGGGCAACTACAACCGCATCTTTGCCAATGCCGATGTCGTGGGC
CGCTTCAACACCGGTTCGATCGCCCACAGGCTGCTTTTTGGCGTCGAGTACCGCCGGGGCCGAGAGTCTCCAATCTTCAA
GACCTCGGAGTTGTACCCCTCTATCAATATCTTCAACCCGGTCTACATCGACCAGGCTTACGCCAAAACCCCGGATTTCT
TTCGCGACGACGACGCCACGACCCTGGCCGCCTACATTCAAGATCAAATCGATCTGCTGCCCAACCTGAAGTTGCTCGCC
GGGGTTCGCTTCGACACCTACCGGCAATCGCGCTCCGAAAACGACCTCAACCAGCCGCGCAGCGTCTTCGTGCAGACCGA
CGGAGCCTGGAGCCCGCGCGTCGGTCTGGTCTGGCAGCCGGCACCGGAAGTGTCGCTCTATGGGTCGTACACGCGCTCTT
TCGTGCCGCAATTCGGCACCTTCCGCAACTTCAACGGCGCCGCCTTCCGGCCGGAGACCGGTACCCAGTGGGAGGTGGGC
GTCAAAACGGAACTATTCGACAAAAAACTGAGCCTAACTCTGGCCGCCTACGATCTGCGCAAACAGAATGTCGTGACCGC
CGATCCCACCAACCCCCTGGTCTCGATCCAGACCGGGGAGCAGACGAGCCGGGGCATCGAATTCGACGCGAGCGGCGAAA
TCCTGCCGGGCTGGAACGTGATTGCCTCCTACTCGCTCATCGACGCGGTGGTCAGCGCCGACAACAGTTTGCCCGTGGGC
AACACCCTGGCCAACGTGCCCGCCAACACCGCCAGTTTTTGGAGCCGCTACAACCTGCAAGGCGGCGATCTCAAGGGTCT
GGGCTTTGGTCTGGGGCTATTTTATGTAGACAGCCGGCCGGGGGATCTGCTGGGCAGCTTCACGCTCGACAGCTACGTGC
GCACCGACGCTGCTTTGTACTACCGTCCCGGCAACTGGCAGGCGGCACTCAACTTCCGCAATCTGTTCGACGTGCGCTAC
TACACCGGCGGTTTTCGCACCGGCGTGCAGCCGGGAGCGCCGTTCACGGTGCTCGGCACGCTGTCGATGGAACTATGA

Upstream 100 bases:

>100_bases
CAACAGCTTTACAGTGGCCACGATGTCAATAACGTTGCTGGGTCTACCGTTTCCCAGCCTTAGGGCCTCAGGAAATCATT
GTTAAACGTTGCGTAGGAGG

Downstream 100 bases:

>100_bases
CGGCGCTCGAGGCGGACTGCTCAAGCTTGCTGGAGAGTTTCGCGCAACCTTTGCACGGCGCGCGGGTGGGTCGTGCGCGT
TCCCAGGAGCACCAGCTCGG

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MVGVGNKAHSGRAGRFVLATLSGVIAQASQVAAIPTATQSEQTIPRLADLEPMQTGAQGLFESPVAQAEPGTQKPPTSPE
DLDEVTVTGTRSYRRSRSSTATKTDTAILDVPQSIQVIPRQVLEDQRIVRAGDALQNVSGIVNLGSYSGYSDSLLIRGFE
AAGFDGSFFRDGVPYFQFDYVETADLERIEVLKGPASVLFGQGQPGGIVNLVSKQPQAKPYYSAALTAGSYSDYRGQLDL
SGPLNAGGTLQYRLNAFYQNARSFRDFVRNDRSVLTPALTWQISPQTALRFDSYFINEARTMDDGIPVIGRSVANVPIGR
FLHEPFSNYRKDEYGLGYSLDHRFSENWSLRHTARYQNVSPERYYPFSLELNEQTGELSRLAYWAAGNYNRIFANADVVG
RFNTGSIAHRLLFGVEYRRGRESPIFKTSELYPSINIFNPVYIDQAYAKTPDFFRDDDATTLAAYIQDQIDLLPNLKLLA
GVRFDTYRQSRSENDLNQPRSVFVQTDGAWSPRVGLVWQPAPEVSLYGSYTRSFVPQFGTFRNFNGAAFRPETGTQWEVG
VKTELFDKKLSLTLAAYDLRKQNVVTADPTNPLVSIQTGEQTSRGIEFDASGEILPGWNVIASYSLIDAVVSADNSLPVG
NTLANVPANTASFWSRYNLQGGDLKGLGFGLGLFYVDSRPGDLLGSFTLDSYVRTDAALYYRPGNWQAALNFRNLFDVRY
YTGGFRTGVQPGAPFTVLGTLSMEL

Sequences:

>Translated_745_residues
MVGVGNKAHSGRAGRFVLATLSGVIAQASQVAAIPTATQSEQTIPRLADLEPMQTGAQGLFESPVAQAEPGTQKPPTSPE
DLDEVTVTGTRSYRRSRSSTATKTDTAILDVPQSIQVIPRQVLEDQRIVRAGDALQNVSGIVNLGSYSGYSDSLLIRGFE
AAGFDGSFFRDGVPYFQFDYVETADLERIEVLKGPASVLFGQGQPGGIVNLVSKQPQAKPYYSAALTAGSYSDYRGQLDL
SGPLNAGGTLQYRLNAFYQNARSFRDFVRNDRSVLTPALTWQISPQTALRFDSYFINEARTMDDGIPVIGRSVANVPIGR
FLHEPFSNYRKDEYGLGYSLDHRFSENWSLRHTARYQNVSPERYYPFSLELNEQTGELSRLAYWAAGNYNRIFANADVVG
RFNTGSIAHRLLFGVEYRRGRESPIFKTSELYPSINIFNPVYIDQAYAKTPDFFRDDDATTLAAYIQDQIDLLPNLKLLA
GVRFDTYRQSRSENDLNQPRSVFVQTDGAWSPRVGLVWQPAPEVSLYGSYTRSFVPQFGTFRNFNGAAFRPETGTQWEVG
VKTELFDKKLSLTLAAYDLRKQNVVTADPTNPLVSIQTGEQTSRGIEFDASGEILPGWNVIASYSLIDAVVSADNSLPVG
NTLANVPANTASFWSRYNLQGGDLKGLGFGLGLFYVDSRPGDLLGSFTLDSYVRTDAALYYRPGNWQAALNFRNLFDVRY
YTGGFRTGVQPGAPFTVLGTLSMEL
>Mature_745_residues
MVGVGNKAHSGRAGRFVLATLSGVIAQASQVAAIPTATQSEQTIPRLADLEPMQTGAQGLFESPVAQAEPGTQKPPTSPE
DLDEVTVTGTRSYRRSRSSTATKTDTAILDVPQSIQVIPRQVLEDQRIVRAGDALQNVSGIVNLGSYSGYSDSLLIRGFE
AAGFDGSFFRDGVPYFQFDYVETADLERIEVLKGPASVLFGQGQPGGIVNLVSKQPQAKPYYSAALTAGSYSDYRGQLDL
SGPLNAGGTLQYRLNAFYQNARSFRDFVRNDRSVLTPALTWQISPQTALRFDSYFINEARTMDDGIPVIGRSVANVPIGR
FLHEPFSNYRKDEYGLGYSLDHRFSENWSLRHTARYQNVSPERYYPFSLELNEQTGELSRLAYWAAGNYNRIFANADVVG
RFNTGSIAHRLLFGVEYRRGRESPIFKTSELYPSINIFNPVYIDQAYAKTPDFFRDDDATTLAAYIQDQIDLLPNLKLLA
GVRFDTYRQSRSENDLNQPRSVFVQTDGAWSPRVGLVWQPAPEVSLYGSYTRSFVPQFGTFRNFNGAAFRPETGTQWEVG
VKTELFDKKLSLTLAAYDLRKQNVVTADPTNPLVSIQTGEQTSRGIEFDASGEILPGWNVIASYSLIDAVVSADNSLPVG
NTLANVPANTASFWSRYNLQGGDLKGLGFGLGLFYVDSRPGDLLGSFTLDSYVRTDAALYYRPGNWQAALNFRNLFDVRY
YTGGFRTGVQPGAPFTVLGTLSMEL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=703, Percent_Identity=31.8634423897582, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1787024, Length=705, Percent_Identity=24.822695035461, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1787344, Length=730, Percent_Identity=23.2876712328767, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82309; Mature: 82309

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGVGNKAHSGRAGRFVLATLSGVIAQASQVAAIPTATQSEQTIPRLADLEPMQTGAQGL
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHCCCHHHHHHHHH
FESPVAQAEPGTQKPPTSPEDLDEVTVTGTRSYRRSRSSTATKTDTAILDVPQSIQVIPR
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCEEEEECCHHHHHHHH
QVLEDQRIVRAGDALQNVSGIVNLGSYSGYSDSLLIRGFEAAGFDGSFFRDGVPYFQFDY
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCHHHCCCCCEEEEC
VETADLERIEVLKGPASVLFGQGQPGGIVNLVSKQPQAKPYYSAALTAGSYSDYRGQLDL
CCCCCCHHHHHHCCCHHEEECCCCCCCEEEECCCCCCCCCCHHEEEECCCCCCCCCEEEE
SGPLNAGGTLQYRLNAFYQNARSFRDFVRNDRSVLTPALTWQISPQTALRFDSYFINEAR
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECEEEEEEECCHHHHHHHHHHHCCHH
TMDDGIPVIGRSVANVPIGRFLHEPFSNYRKDEYGLGYSLDHRFSENWSLRHTARYQNVS
CCCCCCCHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEHHHCCCC
PERYYPFSLELNEQTGELSRLAYWAAGNYNRIFANADVVGRFNTGSIAHRLLFGVEYRRG
CCCCCCEEEEECCCCCCHHHEEEEECCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCC
RESPIFKTSELYPSINIFNPVYIDQAYAKTPDFFRDDDATTLAAYIQDQIDLLPNLKLLA
CCCCCEECHHHCCCCCCCCEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHC
GVRFDTYRQSRSENDLNQPRSVFVQTDGAWSPRVGLVWQPAPEVSLYGSYTRSFVPQFGT
CCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCEEECCCHHHHHCCCCCC
FRNFNGAAFRPETGTQWEVGVKTELFDKKLSLTLAAYDLRKQNVVTADPTNPLVSIQTGE
CCCCCCCEECCCCCCEEEECCCHHHHCCHHEEEEEEEECCCCCEEEECCCCCEEEEECCC
QTSRGIEFDASGEILPGWNVIASYSLIDAVVSADNSLPVGNTLANVPANTASFWSRYNLQ
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHCCCC
GGDLKGLGFGLGLFYVDSRPGDLLGSFTLDSYVRTDAALYYRPGNWQAALNFRNLFDVRY
CCCCCCEEEEEEEEEEECCCCCCEECHHHHHHHCCCEEEEEECCCCEEEEEHHHEEEEEE
YTGGFRTGVQPGAPFTVLGTLSMEL
ECCCEECCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MVGVGNKAHSGRAGRFVLATLSGVIAQASQVAAIPTATQSEQTIPRLADLEPMQTGAQGL
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHCCCHHHHHHHHH
FESPVAQAEPGTQKPPTSPEDLDEVTVTGTRSYRRSRSSTATKTDTAILDVPQSIQVIPR
HHCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCEEEEECCHHHHHHHH
QVLEDQRIVRAGDALQNVSGIVNLGSYSGYSDSLLIRGFEAAGFDGSFFRDGVPYFQFDY
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCHHHCCCCCEEEEC
VETADLERIEVLKGPASVLFGQGQPGGIVNLVSKQPQAKPYYSAALTAGSYSDYRGQLDL
CCCCCCHHHHHHCCCHHEEECCCCCCCEEEECCCCCCCCCCHHEEEECCCCCCCCCEEEE
SGPLNAGGTLQYRLNAFYQNARSFRDFVRNDRSVLTPALTWQISPQTALRFDSYFINEAR
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECEEEEEEECCHHHHHHHHHHHCCHH
TMDDGIPVIGRSVANVPIGRFLHEPFSNYRKDEYGLGYSLDHRFSENWSLRHTARYQNVS
CCCCCCCHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEHHHCCCC
PERYYPFSLELNEQTGELSRLAYWAAGNYNRIFANADVVGRFNTGSIAHRLLFGVEYRRG
CCCCCCEEEEECCCCCCHHHEEEEECCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHCC
RESPIFKTSELYPSINIFNPVYIDQAYAKTPDFFRDDDATTLAAYIQDQIDLLPNLKLLA
CCCCCEECHHHCCCCCCCCEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHC
GVRFDTYRQSRSENDLNQPRSVFVQTDGAWSPRVGLVWQPAPEVSLYGSYTRSFVPQFGT
CCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCEEECCCHHHHHCCCCCC
FRNFNGAAFRPETGTQWEVGVKTELFDKKLSLTLAAYDLRKQNVVTADPTNPLVSIQTGE
CCCCCCCEECCCCCCEEEECCCHHHHCCHHEEEEEEEECCCCCEEEECCCCCEEEEECCC
QTSRGIEFDASGEILPGWNVIASYSLIDAVVSADNSLPVGNTLANVPANTASFWSRYNLQ
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHCCCC
GGDLKGLGFGLGLFYVDSRPGDLLGSFTLDSYVRTDAALYYRPGNWQAALNFRNLFDVRY
CCCCCCEEEEEEEEEEECCCCCCEECHHHHHHHCCCEEEEEECCCCEEEEEHHHEEEEEE
YTGGFRTGVQPGAPFTVLGTLSMEL
ECCCEECCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]