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The map label for this gene is argB

Identifier: 37523500

GI number: 37523500

Start: 4124506

End: 4125417

Strand: Reverse

Name: argB

Synonym: gvip537

Alternate gene names: 37523500

Gene position: 4125417-4124506 (Counterclockwise)

Preceding gene: 37523501

Following gene: 37523493

Centisome position: 88.55

GC content: 61.18

Gene sequence:

>912_bases
GTGTCCCAGGACGCCCCGAGCTGTTTTACCGCCATCATCTCCCCGGCCGACCGCGTGCAGGTGCTGGCCGAGGCGCTGCC
CTACATTCAGCGCTTTGCCGGTAAGACGATCGTCGTCAAGTACGGCGGTGCGGCAATGGTCAAAGAAAACCTGCGCGACC
TGGTCATTCGCGACATCGTGTTTCTGGCCACCGTCGGTATCAAGCCGGTGGTCGTCCATGGCGGCGGGCCCGAGATTAAC
AGCTGGCTGGAGCGGCTCAACATTCCGGTGCAGTTTGTGGGCGGCTTGCGAGTGACCGACAAGATCACCATGGAAGTGGT
GGAGATGGTCCTCGCGGGCAAAGTGAATAAATCGATCGTCCAGATGATCAACCAGGCGGGCGGCTCGGCGGTGGGTCTTT
GCGGTCGCGACGGCTCGATTATCGAGGCGCGTCCCCACCAGAGCGCCCAACTGCAGCCGGACATCGGCTTTGTGGGCGAT
ATCCAGAGCGTCAACCCCAAATTGATTCAGTCGCTGCTCAAAGAAGGTCACATCCCGGTGCTTTCCAGTGTGGCGAGCGA
CGAGAACGGCCAAGCCTACAACATCAACGCCGACACCGCCGCCGGGGAACTCGCAGCGGCCCTCGATGCCGAGAAATTGA
TTCTGCTCACCGATACCCCGGGGATTTTGCTGGACAAAGACCATCCCAGGTCGCTGATTCGAAAACTGGACATCTACCAG
GCCCGCAAACTGATCGCCGAAGGCGTCGTGGACGGGGGCATGATCCCCAAAGTCCAGTGCTGCGTGCGCGCCCTCGCCCA
AGGGGTTCGCGCCGCCCACATCGTCGATGGTCGGCAGATGCATGCGCTCTTGCTGGAGGTGCTTACCGATCAGGGCATCG
GCAGCATGCTGGTTGCCTCGGAACTTGTTTGA

Upstream 100 bases:

>100_bases
ACCGGGTGCTTTCTGCCATCGACCGCCAGATGGCGTATGGTGGTGGGGATTTCGAGGTGTTCGAGCCGTGATCGAAAAGA
CCGGAGATCCTCTAAAGGCG

Downstream 100 bases:

>100_bases
TTGGACGATCAAATTTTGTCAGGATCGACACCTTGATTGCGAAGATACGCCGCCAGGCGTTCCGCTCTTTCTTCGGGGGA
AGGGAACCTTTGCCCGTCTT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSQDAPSCFTAIISPADRVQVLAEALPYIQRFAGKTIVVKYGGAAMVKENLRDLVIRDIVFLATVGIKPVVVHGGGPEIN
SWLERLNIPVQFVGGLRVTDKITMEVVEMVLAGKVNKSIVQMINQAGGSAVGLCGRDGSIIEARPHQSAQLQPDIGFVGD
IQSVNPKLIQSLLKEGHIPVLSSVASDENGQAYNINADTAAGELAAALDAEKLILLTDTPGILLDKDHPRSLIRKLDIYQ
ARKLIAEGVVDGGMIPKVQCCVRALAQGVRAAHIVDGRQMHALLLEVLTDQGIGSMLVASELV

Sequences:

>Translated_303_residues
MSQDAPSCFTAIISPADRVQVLAEALPYIQRFAGKTIVVKYGGAAMVKENLRDLVIRDIVFLATVGIKPVVVHGGGPEIN
SWLERLNIPVQFVGGLRVTDKITMEVVEMVLAGKVNKSIVQMINQAGGSAVGLCGRDGSIIEARPHQSAQLQPDIGFVGD
IQSVNPKLIQSLLKEGHIPVLSSVASDENGQAYNINADTAAGELAAALDAEKLILLTDTPGILLDKDHPRSLIRKLDIYQ
ARKLIAEGVVDGGMIPKVQCCVRALAQGVRAAHIVDGRQMHALLLEVLTDQGIGSMLVASELV
>Mature_302_residues
SQDAPSCFTAIISPADRVQVLAEALPYIQRFAGKTIVVKYGGAAMVKENLRDLVIRDIVFLATVGIKPVVVHGGGPEINS
WLERLNIPVQFVGGLRVTDKITMEVVEMVLAGKVNKSIVQMINQAGGSAVGLCGRDGSIIEARPHQSAQLQPDIGFVGDI
QSVNPKLIQSLLKEGHIPVLSSVASDENGQAYNINADTAAGELAAALDAEKLILLTDTPGILLDKDHPRSLIRKLDIYQA
RKLIAEGVVDGGMIPKVQCCVRALAQGVRAAHIVDGRQMHALLLEVLTDQGIGSMLVASELV

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=252, Percent_Identity=35.3174603174603, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789181, Length=290, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=298, Percent_Identity=28.8590604026846, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_GLOVI (Q7NEE9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926877.1
- ProteinModelPortal:   Q7NEE9
- SMR:   Q7NEE9
- GeneID:   2602334
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3931
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   GVIO251221:GLL3931-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32258; Mature: 32127

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: BINDING 97-97 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDAPSCFTAIISPADRVQVLAEALPYIQRFAGKTIVVKYGGAAMVKENLRDLVIRDIV
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
FLATVGIKPVVVHGGGPEINSWLERLNIPVQFVGGLRVTDKITMEVVEMVLAGKVNKSIV
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHCCCCHHHH
QMINQAGGSAVGLCGRDGSIIEARPHQSAQLQPDIGFVGDIQSVNPKLIQSLLKEGHIPV
HHHHHCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
LSSVASDENGQAYNINADTAAGELAAALDAEKLILLTDTPGILLDKDHPRSLIRKLDIYQ
HHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHH
ARKLIAEGVVDGGMIPKVQCCVRALAQGVRAAHIVDGRQMHALLLEVLTDQGIGSMLVAS
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
ELV
HCC
>Mature Secondary Structure 
SQDAPSCFTAIISPADRVQVLAEALPYIQRFAGKTIVVKYGGAAMVKENLRDLVIRDIV
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
FLATVGIKPVVVHGGGPEINSWLERLNIPVQFVGGLRVTDKITMEVVEMVLAGKVNKSIV
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHCCCCHHHH
QMINQAGGSAVGLCGRDGSIIEARPHQSAQLQPDIGFVGDIQSVNPKLIQSLLKEGHIPV
HHHHHCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
LSSVASDENGQAYNINADTAAGELAAALDAEKLILLTDTPGILLDKDHPRSLIRKLDIYQ
HHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHH
ARKLIAEGVVDGGMIPKVQCCVRALAQGVRAAHIVDGRQMHALLLEVLTDQGIGSMLVAS
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
ELV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292