Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 37523397

GI number: 37523397

Start: 4033280

End: 4034344

Strand: Direct

Name: namA [H]

Synonym: glr3828

Alternate gene names: 37523397

Gene position: 4033280-4034344 (Clockwise)

Preceding gene: 37523396

Following gene: 37523398

Centisome position: 86.57

GC content: 66.76

Gene sequence:

>1065_bases
ATGCACCTGTTTGCACCTTTGACCCTGCGCGACATCACCCTGCGCAACCGCATCGCCGTCTCGCCGATGTGCCAGTACTC
GAGCATCGACGGTCTGGCGAACGATTGGCACTTCGTTCACCTGGGCAGCCGCGCGGTGGGCGGGGCGGGTCTGGTCATTT
TTGAAGCGGCGGCGGTCGAAGCGCGCGGGCGCATCAGCCCCCAGGACCTGGGCATCTGGAGCGACGCGCACATCGAGCCC
TTGCGGCGGATCAACGATTTTATCCATCGCCAGGAGTCAGTGGCCGGGATTCAGATTGCCCACGCCGGGCGCAAGGCGAG
TACAGCCCGTCCCTGGGAAGGCGGCGGGCCACTTACCGAGGGTGAGGGCGGTTGGGCGGACAGCGTCGCCCCGAGTGCCC
TCCCCTTCGACGCAGGGTATCCGGTGCCCGAAGCGCTCGATGAAGCGGGCATCGCCGCGACTGTGCAGGCGTTTGCTGCG
GCGGCAAGGCGGTCGCTGGCAGCCGGATTTCGGGTGCTCGAAATCCATGCCGCCCACGGCTATCTGCTCCATTCCTTTCT
TTCACCCCTGAGCAACCGGCGCACGGACCGGTGGGGGGGACTATTTGAAAACCGCATCCGGCTGTTGCTTGCGGTGGTGG
AGGCGGTGCGCGGTGTCTGGCCCGAGCGCCTGCCGCTTTTTGTGCGCATCTCGGCTACCGATTGGACGGAGGGAGGCTGG
GATCTCGAGCAGTCGGTGCTGCTGGCCCAGGTACTCGCCCGCAGCGGCGTGGATCTGATCGATTGCTCCTCGGGGGGAGT
TATCCCTGGCGTGCGCATCCCGGCGGGGCCGGGCTACCAGACCAGGTTTGCCGAGCGCATCCGGGCTGAGGCGGACATGC
TCACCGGCGCTGTCGGGCAGATCACCTCGGCGGAGCAGGCCGACCACATCGTGCGCACCGGTCAGGCGGATCTGGTGCTC
ATCGGCAGACAATTGTTGCGCGATCCCTACTGGCCCCTCAAAGCGGCGGTCGAATTGCGCGCTCCCGGTCCCTGGCCCGA
ACAGTACCAGCGGGCCAAACCGTGA

Upstream 100 bases:

>100_bases
GCGGTTGTCTGGGCGACTGGAACTGTTCTGGTCCATTGCCGCAGCCAGGATATGCTTCCTGATTGCGGGTATTTTCAAAA
CCTCTCACTCAGGATTCGCT

Downstream 100 bases:

>100_bases
GCCAGTAGGCAGACACAGGGTGATTGACGGGTAGCATCGCCTGCGCTATACCGGTCTCAACGTCGACGCCATCAGCCGCC
AGGGCGTGCGCCGGACCCTA

Product: oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MHLFAPLTLRDITLRNRIAVSPMCQYSSIDGLANDWHFVHLGSRAVGGAGLVIFEAAAVEARGRISPQDLGIWSDAHIEP
LRRINDFIHRQESVAGIQIAHAGRKASTARPWEGGGPLTEGEGGWADSVAPSALPFDAGYPVPEALDEAGIAATVQAFAA
AARRSLAAGFRVLEIHAAHGYLLHSFLSPLSNRRTDRWGGLFENRIRLLLAVVEAVRGVWPERLPLFVRISATDWTEGGW
DLEQSVLLAQVLARSGVDLIDCSSGGVIPGVRIPAGPGYQTRFAERIRAEADMLTGAVGQITSAEQADHIVRTGQADLVL
IGRQLLRDPYWPLKAAVELRAPGPWPEQYQRAKP

Sequences:

>Translated_354_residues
MHLFAPLTLRDITLRNRIAVSPMCQYSSIDGLANDWHFVHLGSRAVGGAGLVIFEAAAVEARGRISPQDLGIWSDAHIEP
LRRINDFIHRQESVAGIQIAHAGRKASTARPWEGGGPLTEGEGGWADSVAPSALPFDAGYPVPEALDEAGIAATVQAFAA
AARRSLAAGFRVLEIHAAHGYLLHSFLSPLSNRRTDRWGGLFENRIRLLLAVVEAVRGVWPERLPLFVRISATDWTEGGW
DLEQSVLLAQVLARSGVDLIDCSSGGVIPGVRIPAGPGYQTRFAERIRAEADMLTGAVGQITSAEQADHIVRTGQADLVL
IGRQLLRDPYWPLKAAVELRAPGPWPEQYQRAKP
>Mature_354_residues
MHLFAPLTLRDITLRNRIAVSPMCQYSSIDGLANDWHFVHLGSRAVGGAGLVIFEAAAVEARGRISPQDLGIWSDAHIEP
LRRINDFIHRQESVAGIQIAHAGRKASTARPWEGGGPLTEGEGGWADSVAPSALPFDAGYPVPEALDEAGIAATVQAFAA
AARRSLAAGFRVLEIHAAHGYLLHSFLSPLSNRRTDRWGGLFENRIRLLLAVVEAVRGVWPERLPLFVRISATDWTEGGW
DLEQSVLLAQVLARSGVDLIDCSSGGVIPGVRIPAGPGYQTRFAERIRAEADMLTGAVGQITSAEQADHIVRTGQADLVL
IGRQLLRDPYWPLKAAVELRAPGPWPEQYQRAKP

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=344, Percent_Identity=30.2325581395349, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789463, Length=341, Percent_Identity=28.1524926686217, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=29.7752808988764, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=179, Percent_Identity=31.2849162011173, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=178, Percent_Identity=29.7752808988764, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=179, Percent_Identity=29.608938547486, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=184, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=284, Percent_Identity=29.2253521126761, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=209, Percent_Identity=25.8373205741627, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=246, Percent_Identity=28.0487804878049, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=246, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38364; Mature: 38364

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLFAPLTLRDITLRNRIAVSPMCQYSSIDGLANDWHFVHLGSRAVGGAGLVIFEAAAVE
CCEECCCEEEHHHHHCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHH
ARGRISPQDLGIWSDAHIEPLRRINDFIHRQESVAGIQIAHAGRKASTARPWEGGGPLTE
HCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCC
GEGGWADSVAPSALPFDAGYPVPEALDEAGIAATVQAFAAAARRSLAAGFRVLEIHAAHG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHH
YLLHSFLSPLSNRRTDRWGGLFENRIRLLLAVVEAVRGVWPERLPLFVRISATDWTEGGW
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DLEQSVLLAQVLARSGVDLIDCSSGGVIPGVRIPAGPGYQTRFAERIRAEADMLTGAVGQ
CHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ITSAEQADHIVRTGQADLVLIGRQLLRDPYWPLKAAVELRAPGPWPEQYQRAKP
CCCHHHHHHHHHCCCCCHHHCCHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure
MHLFAPLTLRDITLRNRIAVSPMCQYSSIDGLANDWHFVHLGSRAVGGAGLVIFEAAAVE
CCEECCCEEEHHHHHCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHH
ARGRISPQDLGIWSDAHIEPLRRINDFIHRQESVAGIQIAHAGRKASTARPWEGGGPLTE
HCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCC
GEGGWADSVAPSALPFDAGYPVPEALDEAGIAATVQAFAAAARRSLAAGFRVLEIHAAHG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHH
YLLHSFLSPLSNRRTDRWGGLFENRIRLLLAVVEAVRGVWPERLPLFVRISATDWTEGGW
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DLEQSVLLAQVLARSGVDLIDCSSGGVIPGVRIPAGPGYQTRFAERIRAEADMLTGAVGQ
CHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ITSAEQADHIVRTGQADLVLIGRQLLRDPYWPLKAAVELRAPGPWPEQYQRAKP
CCCHHHHHHHHHCCCCCHHHCCHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA