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The map label for this gene is yqhD [H]

Identifier: 37523396

GI number: 37523396

Start: 4031957

End: 4033111

Strand: Direct

Name: yqhD [H]

Synonym: glr3827

Alternate gene names: 37523396

Gene position: 4031957-4033111 (Clockwise)

Preceding gene: 37523394

Following gene: 37523397

Centisome position: 86.54

GC content: 63.55

Gene sequence:

>1155_bases
ATGAAAAATTTCACGTTCTACAATCCGGTCAAGATTCTTTTCGGCAAAGGTCAGATTGCCCGTCTGGCTGCGGAGATTCC
AGTTACAGCCCGCATCCTGCTCACCTACGGCGGCGGCAGCATCAAGGCCAACGGCGTCTACGACCAGGTCAAAGCTGCCC
TTGCCGGCCACACGGTTTTCGAGTTCGGCGGCATCGAGCCCAATCCGCACCTGGAGACGCTCCTCAAAGCAGTCGAGGTG
GTCCGCGCCGAGAACATCGACTTTTTGCTCGCAGTGGGAGGCGGCTCGGTGGCTGACGGCACCAAGTTTATCGCCGCCGC
CGCCCGCTTCGAAGCTGATCCCTGGGACATCCTGGCCAAGCAGGCACCGATCACCGCTGCCGTGCCCCTGGGAACGGTGC
TCACCCTGCCTGCCACCGGTTCCGAGATGAACGGCACGGCGGTGGTCACCCGGGCCGCCACCCGGGAGAAACTCTACTTC
GGCAGTCCCCTGGTCATGCCGGTCTTCTCGGTGCTCGACCCCGAGACCACCTTCTCGCTGCCGCCCAAGCAAATCGGCAA
CGGCATCGTCGATGCTTTTACCCACGTTGCCGAGCAGTACCTCACCTATCCGGTCGGGGCGCCTTTGCAGGACCGCATGG
CGGAGGCGATTCTCAAGACGCTCATCGAGGAAGGACCGAAGACCCTGGCCAATCCCACCGACTACGCGGCGCGGGCCAAT
TTTATGTGGTGCGCCACCATGGCCCTCAACGGCATGATTGGTGCCGGTGTTCCCCACGATTGGGCGACCCACACCATCGG
CCACGAACTGACCGCTTTGCACGGTATCGACCACGGCCGCACCCTCGCCATCGTGCTGCCGAGTGTCCTCACCCTCAAGC
GCGACAGCAAGCGCGCCAAGTTGTTGCAGTACGCCGAGTGGGTCTGGGGGATCACCACCGGTACCGAAGAAGAGCGCATC
GACGCGGCCATCGGGCGCACCCGCGCCTTTTTCGAATCGGTGGGAGTGCCCACACGCCTGGGCGACTACGGTGTGCCCAC
CGAGACGATCCCGCTCATCGTCGAGCGTCTCGAAAATCGTGGTGCGGTTGCCCTCGGCGAGCACGGCGACATCGACCCGG
CGGCGGTCGACAAAGTCCTGGCCCTCAGCGTTTAG

Upstream 100 bases:

>100_bases
CTTGGCCGCCGGGATTGACTTTTCAGAGACGACTGGTCTAATCTGAGGGCAGTTGAGACGACTGGTCTATTCGAGACCTT
CTGGAGCAAGCCACAGCCCT

Downstream 100 bases:

>100_bases
GCAGGTGTCAGGTTGCCGGTGTCAGGCGTCAGGGTTGGGAACCGTCGTATTGGGTTTTCGGTCGGCCTGCGGTTGTCTGG
GCGACTGGAACTGTTCTGGT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKNFTFYNPVKILFGKGQIARLAAEIPVTARILLTYGGGSIKANGVYDQVKAALAGHTVFEFGGIEPNPHLETLLKAVEV
VRAENIDFLLAVGGGSVADGTKFIAAAARFEADPWDILAKQAPITAAVPLGTVLTLPATGSEMNGTAVVTRAATREKLYF
GSPLVMPVFSVLDPETTFSLPPKQIGNGIVDAFTHVAEQYLTYPVGAPLQDRMAEAILKTLIEEGPKTLANPTDYAARAN
FMWCATMALNGMIGAGVPHDWATHTIGHELTALHGIDHGRTLAIVLPSVLTLKRDSKRAKLLQYAEWVWGITTGTEEERI
DAAIGRTRAFFESVGVPTRLGDYGVPTETIPLIVERLENRGAVALGEHGDIDPAAVDKVLALSV

Sequences:

>Translated_384_residues
MKNFTFYNPVKILFGKGQIARLAAEIPVTARILLTYGGGSIKANGVYDQVKAALAGHTVFEFGGIEPNPHLETLLKAVEV
VRAENIDFLLAVGGGSVADGTKFIAAAARFEADPWDILAKQAPITAAVPLGTVLTLPATGSEMNGTAVVTRAATREKLYF
GSPLVMPVFSVLDPETTFSLPPKQIGNGIVDAFTHVAEQYLTYPVGAPLQDRMAEAILKTLIEEGPKTLANPTDYAARAN
FMWCATMALNGMIGAGVPHDWATHTIGHELTALHGIDHGRTLAIVLPSVLTLKRDSKRAKLLQYAEWVWGITTGTEEERI
DAAIGRTRAFFESVGVPTRLGDYGVPTETIPLIVERLENRGAVALGEHGDIDPAAVDKVLALSV
>Mature_384_residues
MKNFTFYNPVKILFGKGQIARLAAEIPVTARILLTYGGGSIKANGVYDQVKAALAGHTVFEFGGIEPNPHLETLLKAVEV
VRAENIDFLLAVGGGSVADGTKFIAAAARFEADPWDILAKQAPITAAVPLGTVLTLPATGSEMNGTAVVTRAATREKLYF
GSPLVMPVFSVLDPETTFSLPPKQIGNGIVDAFTHVAEQYLTYPVGAPLQDRMAEAILKTLIEEGPKTLANPTDYAARAN
FMWCATMALNGMIGAGVPHDWATHTIGHELTALHGIDHGRTLAIVLPSVLTLKRDSKRAKLLQYAEWVWGITTGTEEERI
DAAIGRTRAFFESVGVPTRLGDYGVPTETIPLIVERLENRGAVALGEHGDIDPAAVDKVLALSV

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=374, Percent_Identity=60.9625668449198, Blast_Score=463, Evalue=1e-132,
Organism=Escherichia coli, GI48994951, Length=312, Percent_Identity=24.6794871794872, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082107, Length=279, Percent_Identity=27.2401433691756, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789163, Length=355, Percent_Identity=25.6338028169014, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787493, Length=352, Percent_Identity=25.2840909090909, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321181, Length=358, Percent_Identity=25.6983240223464, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41032; Mature: 41032

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFTFYNPVKILFGKGQIARLAAEIPVTARILLTYGGGSIKANGVYDQVKAALAGHTVF
CCCCCEECCEEEEECCCHHHHHHHCCCCEEEEEEEECCCCEEECCHHHHHHHHHHCCCEE
EFGGIEPNPHLETLLKAVEVVRAENIDFLLAVGGGSVADGTKFIAAAARFEADPWDILAK
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHC
QAPITAAVPLGTVLTLPATGSEMNGTAVVTRAATREKLYFGSPLVMPVFSVLDPETTFSL
CCCCEEECCCCEEEEECCCCCCCCCCEEEEEHHHHHHEECCCCHHHHHHHHCCCCCCCCC
PPKQIGNGIVDAFTHVAEQYLTYPVGAPLQDRMAEAILKTLIEEGPKTLANPTDYAARAN
CHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHCC
FMWCATMALNGMIGAGVPHDWATHTIGHELTALHGIDHGRTLAIVLPSVLTLKRDSKRAK
HHEEHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHH
LLQYAEWVWGITTGTEEERIDAAIGRTRAFFESVGVPTRLGDYGVPTETIPLIVERLENR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
GAVALGEHGDIDPAAVDKVLALSV
CCEEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKNFTFYNPVKILFGKGQIARLAAEIPVTARILLTYGGGSIKANGVYDQVKAALAGHTVF
CCCCCEECCEEEEECCCHHHHHHHCCCCEEEEEEEECCCCEEECCHHHHHHHHHHCCCEE
EFGGIEPNPHLETLLKAVEVVRAENIDFLLAVGGGSVADGTKFIAAAARFEADPWDILAK
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHC
QAPITAAVPLGTVLTLPATGSEMNGTAVVTRAATREKLYFGSPLVMPVFSVLDPETTFSL
CCCCEEECCCCEEEEECCCCCCCCCCEEEEEHHHHHHEECCCCHHHHHHHHCCCCCCCCC
PPKQIGNGIVDAFTHVAEQYLTYPVGAPLQDRMAEAILKTLIEEGPKTLANPTDYAARAN
CHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHCC
FMWCATMALNGMIGAGVPHDWATHTIGHELTALHGIDHGRTLAIVLPSVLTLKRDSKRAK
HHEEHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHH
LLQYAEWVWGITTGTEEERIDAAIGRTRAFFESVGVPTRLGDYGVPTETIPLIVERLENR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
GAVALGEHGDIDPAAVDKVLALSV
CCEEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]