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The map label for this gene is dnaK [H]

Identifier: 37523371

GI number: 37523371

Start: 4009883

End: 4011418

Strand: Reverse

Name: dnaK [H]

Synonym: gll3802

Alternate gene names: 37523371

Gene position: 4011418-4009883 (Counterclockwise)

Preceding gene: 37523372

Following gene: 37523368

Centisome position: 86.1

GC content: 66.99

Gene sequence:

>1536_bases
GTGAGCATCGTCGCCGTCGATTTCGGCACCTCCAACACGGTGGTATGCCTCGAAAACCGGGCCAGGGGCACCCCCGAAAC
CCTCGTCTTTCCGTTTAGCGCCCACTACCCGGGCGGACCGCCCCTGGTGCCCTCGGCGGTCTATATCGACAGCCGGGGCG
AAGCGCTCATCGGCCGGCCGGCCGCCGCCGCCACCGACAAAAGCCGGCTCTTTCGAGGGTTCAAGCGCGACCTGTCCCAG
GAATTCGAACCCTCGCCCCGGCTGGTGGACGGAGCGAGCTACACCTCGGCGCGGGTGGGCGAAATCTTTTTGGATCGTCT
GTACGCCGCCCTCAACGCCCAGGGCGTCCTGCCTTCACAACTGATTTTGAGCGCACCGGTCGGGGCCTACGAACACTATC
TCAACTGGTTGCGCGAAGCCTGCTTCCGGCTTGCCCTTCCCGAGCCGCTGGTGGTGGACGAATCGACGGCGGCGGCGCTG
GGGTACGCCATCGAGGCGCCGGGAGCGCTGGTGCTGGTGGTCGATCTAGGCGGCGGCACCCTCGATCTCTCGCTGGTGCG
CACAAGCCCCCTGCCCACAGGAGCGCGCGAGCAACGGGCGGAGGTGATCGCCAAATCCGACCGGCCCTGGGGTTGCGGGG
GCGCCGATATCGATCAGTGGATCGCCGAGGATTATCTGGATAGAGCCGGTCTTACCCGCCGCAGTATCGGCGAAACCGCC
TGGCAGAATTTGCTCCTGGTAGCCGAAGCGGTGAAGATCCGGCTTTCCGCTCAGCGCTTCGCCGCCGAGAGCTGGTTTGA
CGAGCAGAGCTTCGAGACCCACGAGTTGCGCCTCGATCGCGACGGCCTGGAGGCGATCCTGGAGCGGCAACAGCTCCTGG
ATCGCCTGCGCGAGGCGGTCGACGAAGTGCTCGATCAGGCCTACGGCCGGGGGGTGGCCAAAAAGGAGATCGCCCACGTC
GTGCTGGTGGGGGGCACCGGCTTGATCCCGGCGGTCCGCAAGCAGCTAATCGGCCTGTTCGGCCGCGAGAAAGTCCGGTT
CGGCAAACCCTTTGAGGCGGTGGCCCACGGCGCGCTCACCCTGGCGCGCTACGGCGCGGTGGAGGACCACCTGCGCCACA
CCTACGCCCTGCGCCACTGGAATCCCTATGCCAAGGCCTACGAATACCTGCCCCTGTTCACAGGCGGCACCCCCTACCCG
GTGGCGGGCGAACCGATTTTGCTGCAGGCCAACGCCGCCGGCCAGAAGGAGGTGAGCCTGGTCCTGGGCGAATTGAGCGC
CGGGACGACCACCGAAGTCTACGAAGATGCCGCCGGCATGCTGCGCACCCGCCCAGGCAGTGCCGACGGCAGCTTCCGGC
CTTTGGGCAAACGCAATCAGGTGAATTTCACCCTCGATCCGCCCGGGGTGGCTGGGGTGGACCGCTTGGAAGTGCGCTTC
GCCGTCGATGGCACCCGCACGCTGCGGGTGACGGTGCGGGATCTGTCCACCGGCCGGTTGCTCGTCGACGAGCAACCGGC
CGGCCGGCTGAAATAA

Upstream 100 bases:

>100_bases
CGGGCGAGACCGTCTACGTGCGCTTTTTGGGCTACCGGGACCAAGCGGAGGTGCTCTGCCGGGCGAAGGTGAGCCGGACG
TTGCCCGCGGGGAGCGGATC

Downstream 100 bases:

>100_bases
GCGCTCCTGCCCCTAGTCCAGGCCGTAATCCTCCTTGAGCGAGCGCATAAAGGCCGCGAGCGCCGCCACATCGTCCTGCA
CCAGGGCGATGCGCCCGATT

Product: hypothetical protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSIVAVDFGTSNTVVCLENRARGTPETLVFPFSAHYPGGPPLVPSAVYIDSRGEALIGRPAAAATDKSRLFRGFKRDLSQ
EFEPSPRLVDGASYTSARVGEIFLDRLYAALNAQGVLPSQLILSAPVGAYEHYLNWLREACFRLALPEPLVVDESTAAAL
GYAIEAPGALVLVVDLGGGTLDLSLVRTSPLPTGAREQRAEVIAKSDRPWGCGGADIDQWIAEDYLDRAGLTRRSIGETA
WQNLLLVAEAVKIRLSAQRFAAESWFDEQSFETHELRLDRDGLEAILERQQLLDRLREAVDEVLDQAYGRGVAKKEIAHV
VLVGGTGLIPAVRKQLIGLFGREKVRFGKPFEAVAHGALTLARYGAVEDHLRHTYALRHWNPYAKAYEYLPLFTGGTPYP
VAGEPILLQANAAGQKEVSLVLGELSAGTTTEVYEDAAGMLRTRPGSADGSFRPLGKRNQVNFTLDPPGVAGVDRLEVRF
AVDGTRTLRVTVRDLSTGRLLVDEQPAGRLK

Sequences:

>Translated_511_residues
MSIVAVDFGTSNTVVCLENRARGTPETLVFPFSAHYPGGPPLVPSAVYIDSRGEALIGRPAAAATDKSRLFRGFKRDLSQ
EFEPSPRLVDGASYTSARVGEIFLDRLYAALNAQGVLPSQLILSAPVGAYEHYLNWLREACFRLALPEPLVVDESTAAAL
GYAIEAPGALVLVVDLGGGTLDLSLVRTSPLPTGAREQRAEVIAKSDRPWGCGGADIDQWIAEDYLDRAGLTRRSIGETA
WQNLLLVAEAVKIRLSAQRFAAESWFDEQSFETHELRLDRDGLEAILERQQLLDRLREAVDEVLDQAYGRGVAKKEIAHV
VLVGGTGLIPAVRKQLIGLFGREKVRFGKPFEAVAHGALTLARYGAVEDHLRHTYALRHWNPYAKAYEYLPLFTGGTPYP
VAGEPILLQANAAGQKEVSLVLGELSAGTTTEVYEDAAGMLRTRPGSADGSFRPLGKRNQVNFTLDPPGVAGVDRLEVRF
AVDGTRTLRVTVRDLSTGRLLVDEQPAGRLK
>Mature_510_residues
SIVAVDFGTSNTVVCLENRARGTPETLVFPFSAHYPGGPPLVPSAVYIDSRGEALIGRPAAAATDKSRLFRGFKRDLSQE
FEPSPRLVDGASYTSARVGEIFLDRLYAALNAQGVLPSQLILSAPVGAYEHYLNWLREACFRLALPEPLVVDESTAAALG
YAIEAPGALVLVVDLGGGTLDLSLVRTSPLPTGAREQRAEVIAKSDRPWGCGGADIDQWIAEDYLDRAGLTRRSIGETAW
QNLLLVAEAVKIRLSAQRFAAESWFDEQSFETHELRLDRDGLEAILERQQLLDRLREAVDEVLDQAYGRGVAKKEIAHVV
LVGGTGLIPAVRKQLIGLFGREKVRFGKPFEAVAHGALTLARYGAVEDHLRHTYALRHWNPYAKAYEYLPLFTGGTPYPV
AGEPILLQANAAGQKEVSLVLGELSAGTTTEVYEDAAGMLRTRPGSADGSFRPLGKRNQVNFTLDPPGVAGVDRLEVRFA
VDGTRTLRVTVRDLSTGRLLVDEQPAGRLK

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI24234688, Length=544, Percent_Identity=24.4485294117647, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI16507237, Length=372, Percent_Identity=28.7634408602151, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI34419635, Length=538, Percent_Identity=26.0223048327138, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1786196, Length=547, Percent_Identity=25.0457038391225, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786870, Length=370, Percent_Identity=25.1351351351351, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17534771, Length=542, Percent_Identity=25.830258302583, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17568549, Length=362, Percent_Identity=29.8342541436464, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17534015, Length=363, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17534013, Length=363, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322505, Length=541, Percent_Identity=25.3234750462107, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320805, Length=549, Percent_Identity=25.5009107468124, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319314, Length=365, Percent_Identity=27.6712328767123, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324120, Length=220, Percent_Identity=32.2727272727273, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319972, Length=220, Percent_Identity=32.2727272727273, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323004, Length=365, Percent_Identity=27.6712328767123, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320950, Length=428, Percent_Identity=25.7009345794392, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319396, Length=277, Percent_Identity=27.0758122743682, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323401, Length=365, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653595, Length=540, Percent_Identity=24.4444444444444, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24641406, Length=361, Percent_Identity=28.5318559556787, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641408, Length=361, Percent_Identity=28.5318559556787, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641402, Length=361, Percent_Identity=28.5318559556787, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641404, Length=361, Percent_Identity=28.5318559556787, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17647515, Length=368, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24663992, Length=368, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24663988, Length=368, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 55565; Mature: 55434

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVAVDFGTSNTVVCLENRARGTPETLVFPFSAHYPGGPPLVPSAVYIDSRGEALIGRP
CEEEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEECCC
AAAATDKSRLFRGFKRDLSQEFEPSPRLVDGASYTSARVGEIFLDRLYAALNAQGVLPSQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LILSAPVGAYEHYLNWLREACFRLALPEPLVVDESTAAALGYAIEAPGALVLVVDLGGGT
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCEEEECCCEEEEEEECCCCE
LDLSLVRTSPLPTGAREQRAEVIAKSDRPWGCGGADIDQWIAEDYLDRAGLTRRSIGETA
EEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
WQNLLLVAEAVKIRLSAQRFAAESWFDEQSFETHELRLDRDGLEAILERQQLLDRLREAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHH
DEVLDQAYGRGVAKKEIAHVVLVGGTGLIPAVRKQLIGLFGREKVRFGKPFEAVAHGALT
HHHHHHHHCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LARYGAVEDHLRHTYALRHWNPYAKAYEYLPLFTGGTPYPVAGEPILLQANAAGQKEVSL
HHHHCCHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCHHHEE
VLGELSAGTTTEVYEDAAGMLRTRPGSADGSFRPLGKRNQVNFTLDPPGVAGVDRLEVRF
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEE
AVDGTRTLRVTVRDLSTGRLLVDEQPAGRLK
EECCCEEEEEEEEECCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SIVAVDFGTSNTVVCLENRARGTPETLVFPFSAHYPGGPPLVPSAVYIDSRGEALIGRP
EEEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEECCC
AAAATDKSRLFRGFKRDLSQEFEPSPRLVDGASYTSARVGEIFLDRLYAALNAQGVLPSQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
LILSAPVGAYEHYLNWLREACFRLALPEPLVVDESTAAALGYAIEAPGALVLVVDLGGGT
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCEEEECCCEEEEEEECCCCE
LDLSLVRTSPLPTGAREQRAEVIAKSDRPWGCGGADIDQWIAEDYLDRAGLTRRSIGETA
EEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
WQNLLLVAEAVKIRLSAQRFAAESWFDEQSFETHELRLDRDGLEAILERQQLLDRLREAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHH
DEVLDQAYGRGVAKKEIAHVVLVGGTGLIPAVRKQLIGLFGREKVRFGKPFEAVAHGALT
HHHHHHHHCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LARYGAVEDHLRHTYALRHWNPYAKAYEYLPLFTGGTPYPVAGEPILLQANAAGQKEVSL
HHHHCCHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCHHHEE
VLGELSAGTTTEVYEDAAGMLRTRPGSADGSFRPLGKRNQVNFTLDPPGVAGVDRLEVRF
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEE
AVDGTRTLRVTVRDLSTGRLLVDEQPAGRLK
EECCCEEEEEEEEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA