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The map label for this gene is 37523256

Identifier: 37523256

GI number: 37523256

Start: 3894243

End: 3895709

Strand: Direct

Name: 37523256

Synonym: glr3687

Alternate gene names: NA

Gene position: 3894243-3895709 (Clockwise)

Preceding gene: 37523255

Following gene: 37523260

Centisome position: 83.59

GC content: 68.78

Gene sequence:

>1467_bases
ATGAAAACGTTGTGTTGGGCGCTGACGGCGATGCTCCTGGCCCCGGGAACGGCGGCTACCGCCCAGACGCAGACCCCGCC
TCCTCCGGGGCCGCCCCCTTCGGTCAGCTACCCGACCCCGGTCGAGCGCACCCTCGCAAACGGCCTGCGGGTGATCGCCG
TGCAGCGCCCGAACGTGCCGCTGGTGGCCGCGCAGTTGATTGTCAAAAGCGGCAGCGAGACCGATCCGCCCGCGCGCCCC
GGCATCGCCTCGCTGGCTGCCGACCTGCTCGACAAAGGCACCAAGACCCGCAGCGCCCTGGAGATTGCCCAGGCCATCGA
CGCGCTTGGAGCGGAGCTGGAGGCCGGTGCCGGCTTCGATGCGACCCGCGTGGAGGTGAGCGCCACCACACCCCAGTTCG
GGCGGGCCTTCGCCATCCTCTCCGAGGTGGTGCGCACCCCCGCCTTTGCCCCCGCTGAAATTGCCCGGGCCAAAACCCAG
GCGATCAGCAATCTGCAACTGGCCTACAGCAATCCTTCGGCCCTGGCGCAGCTGGTGGCGCAGCGGCTGATCTACGGCGA
AGCCCCCTACGGTCAACCGGCCGAGGGCACCCCCGCATCGCTCGGCGCCATCGCCCGCGCCGACTTGGAGCGCTTCCACC
GCACTTACTTCCGGCCGGACAACGCCGTGCTCGTGCTCGGAGGAGACATCGCCCCAGAAGCAGCTTTTGCCGAGGCCGAG
CGCGTCTTCGGCAACTGGGCCAAACCCGCCGCCCCACTTCCGGCTTTCCCCGCAGATAAACGCGACACCGCTTCGCGCGT
CGTGGTGATCGATCAGCCCGAGGCGGGCCGCACGGCGGTGGCCGTGGGTAAAGCGGTACTCCGCCGCGCCGATCCGGCCT
ACATCCTGGGGGTGGTCACCAACGCCGTGATCACCGGTTACTCGGGCCGGCTCAATGCCGAGGTGCGCATCAAGCGGGGA
CTGTCCTACGGCGCCGGCGCCAGCCTGGTGGGCCGCCGCGAGCCGGGGCCGTTTGTCGCCGCCACCCTGGTGGATCACGC
CAAAGCCGCCGAGGCCACCCAGGTGGTGATCGACACCCTCGCAAGCCTGGTGGGTCAACCTGCAGGGGCTGAAGAACTGA
AGCCGCGCAAGGCGGTCATCACCGGCGGCTTCGCCCGTTCGCTCGAAACGATCGACGGCCTGGTGAACCAGGTGGGCACC
CTCGCCCTCTACGGCTTGCCCCTGGGGCAGATCAACACCTTCATCGGCGAGGCGGAGGCGGTCACCCCCCTCAAAGTCCA
GGAATTTGCCGCGGGCTATCTGCAGTCCAACCAATCGGTGGTGCTGGTGGGCAACGCCAAGGCGTTTCTGCCCGACCTGC
GCAAGCGCTTTGCTGAACGCGCCTCCCGCATCGAGGTGATCCCCTTCCAGCGCCTCGATCTTGGCCGGGCGAGCCTGGTG
CGTCCCACGGGAGTTGCCGGAAAGTAA

Upstream 100 bases:

>100_bases
TCGCCCGCCAGTATCTGGTGCCCACCAACCGCACCGTCATCGACTACCTGCCCCGGGCGATGCAACCGGCCGGACCCACC
AAAAAGGAGCGCAAGTCGCC

Downstream 100 bases:

>100_bases
CCGCGCCGCGCCAAAGCACGGCGGGCGCGCTCACTCAGCCTGACGCCGCCGGCATCGAGCCGGAAGTCGCTTTCAGGGTG
TTTCCGGGCGATTGATCACG

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKTLCWALTAMLLAPGTAATAQTQTPPPPGPPPSVSYPTPVERTLANGLRVIAVQRPNVPLVAAQLIVKSGSETDPPARP
GIASLAADLLDKGTKTRSALEIAQAIDALGAELEAGAGFDATRVEVSATTPQFGRAFAILSEVVRTPAFAPAEIARAKTQ
AISNLQLAYSNPSALAQLVAQRLIYGEAPYGQPAEGTPASLGAIARADLERFHRTYFRPDNAVLVLGGDIAPEAAFAEAE
RVFGNWAKPAAPLPAFPADKRDTASRVVVIDQPEAGRTAVAVGKAVLRRADPAYILGVVTNAVITGYSGRLNAEVRIKRG
LSYGAGASLVGRREPGPFVAATLVDHAKAAEATQVVIDTLASLVGQPAGAEELKPRKAVITGGFARSLETIDGLVNQVGT
LALYGLPLGQINTFIGEAEAVTPLKVQEFAAGYLQSNQSVVLVGNAKAFLPDLRKRFAERASRIEVIPFQRLDLGRASLV
RPTGVAGK

Sequences:

>Translated_488_residues
MKTLCWALTAMLLAPGTAATAQTQTPPPPGPPPSVSYPTPVERTLANGLRVIAVQRPNVPLVAAQLIVKSGSETDPPARP
GIASLAADLLDKGTKTRSALEIAQAIDALGAELEAGAGFDATRVEVSATTPQFGRAFAILSEVVRTPAFAPAEIARAKTQ
AISNLQLAYSNPSALAQLVAQRLIYGEAPYGQPAEGTPASLGAIARADLERFHRTYFRPDNAVLVLGGDIAPEAAFAEAE
RVFGNWAKPAAPLPAFPADKRDTASRVVVIDQPEAGRTAVAVGKAVLRRADPAYILGVVTNAVITGYSGRLNAEVRIKRG
LSYGAGASLVGRREPGPFVAATLVDHAKAAEATQVVIDTLASLVGQPAGAEELKPRKAVITGGFARSLETIDGLVNQVGT
LALYGLPLGQINTFIGEAEAVTPLKVQEFAAGYLQSNQSVVLVGNAKAFLPDLRKRFAERASRIEVIPFQRLDLGRASLV
RPTGVAGK
>Mature_488_residues
MKTLCWALTAMLLAPGTAATAQTQTPPPPGPPPSVSYPTPVERTLANGLRVIAVQRPNVPLVAAQLIVKSGSETDPPARP
GIASLAADLLDKGTKTRSALEIAQAIDALGAELEAGAGFDATRVEVSATTPQFGRAFAILSEVVRTPAFAPAEIARAKTQ
AISNLQLAYSNPSALAQLVAQRLIYGEAPYGQPAEGTPASLGAIARADLERFHRTYFRPDNAVLVLGGDIAPEAAFAEAE
RVFGNWAKPAAPLPAFPADKRDTASRVVVIDQPEAGRTAVAVGKAVLRRADPAYILGVVTNAVITGYSGRLNAEVRIKRG
LSYGAGASLVGRREPGPFVAATLVDHAKAAEATQVVIDTLASLVGQPAGAEELKPRKAVITGGFARSLETIDGLVNQVGT
LALYGLPLGQINTFIGEAEAVTPLKVQEFAAGYLQSNQSVVLVGNAKAFLPDLRKRFAERASRIEVIPFQRLDLGRASLV
RPTGVAGK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=265, Percent_Identity=24.1509433962264, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI46593007, Length=416, Percent_Identity=22.5961538461538, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323192, Length=285, Percent_Identity=22.4561403508772, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646943, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR007863 [H]

Pfam domain/function: PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 50927; Mature: 50927

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLCWALTAMLLAPGTAATAQTQTPPPPGPPPSVSYPTPVERTLANGLRVIAVQRPNVP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEECCCCC
LVAAQLIVKSGSETDPPARPGIASLAADLLDKGTKTRSALEIAQAIDALGAELEAGAGFD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ATRVEVSATTPQFGRAFAILSEVVRTPAFAPAEIARAKTQAISNLQLAYSNPSALAQLVA
CEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHH
QRLIYGEAPYGQPAEGTPASLGAIARADLERFHRTYFRPDNAVLVLGGDIAPEAAFAEAE
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
RVFGNWAKPAAPLPAFPADKRDTASRVVVIDQPEAGRTAVAVGKAVLRRADPAYILGVVT
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
NAVITGYSGRLNAEVRIKRGLSYGAGASLVGRREPGPFVAATLVDHAKAAEATQVVIDTL
HHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLVGQPAGAEELKPRKAVITGGFARSLETIDGLVNQVGTLALYGLPLGQINTFIGEAEA
HHHHCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
VTPLKVQEFAAGYLQSNQSVVLVGNAKAFLPDLRKRFAERASRIEVIPFQRLDLGRASLV
CCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCEEECCCHHCCCCCHHCC
RPTGVAGK
CCCCCCCC
>Mature Secondary Structure
MKTLCWALTAMLLAPGTAATAQTQTPPPPGPPPSVSYPTPVERTLANGLRVIAVQRPNVP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEECCCCC
LVAAQLIVKSGSETDPPARPGIASLAADLLDKGTKTRSALEIAQAIDALGAELEAGAGFD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ATRVEVSATTPQFGRAFAILSEVVRTPAFAPAEIARAKTQAISNLQLAYSNPSALAQLVA
CEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHH
QRLIYGEAPYGQPAEGTPASLGAIARADLERFHRTYFRPDNAVLVLGGDIAPEAAFAEAE
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
RVFGNWAKPAAPLPAFPADKRDTASRVVVIDQPEAGRTAVAVGKAVLRRADPAYILGVVT
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
NAVITGYSGRLNAEVRIKRGLSYGAGASLVGRREPGPFVAATLVDHAKAAEATQVVIDTL
HHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLVGQPAGAEELKPRKAVITGGFARSLETIDGLVNQVGTLALYGLPLGQINTFIGEAEA
HHHHCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
VTPLKVQEFAAGYLQSNQSVVLVGNAKAFLPDLRKRFAERASRIEVIPFQRLDLGRASLV
CCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCEEECCCHHCCCCCHHCC
RPTGVAGK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]