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The map label for this gene is pqqL [C]

Identifier: 37523255

GI number: 37523255

Start: 3892777

End: 3894246

Strand: Direct

Name: pqqL [C]

Synonym: glr3686

Alternate gene names: 37523255

Gene position: 3892777-3894246 (Clockwise)

Preceding gene: 37523253

Following gene: 37523256

Centisome position: 83.55

GC content: 64.63

Gene sequence:

>1470_bases
GTGCGAAATTCTAGCAGATGCACCAGGGGAACTCTTGACACCGCCCCCCGTCGGTGGGATAACGTTTTGGACTTGACGGA
GCTTTTCGTGGGCCGTTTTTTGCTGGGCCTAATGCTGGCCGGGACGCTGTCGCTCGGGGCGGCGGTGCGGGCTGAGAGCG
AGGCTGTTCCCCTGCCTCCGGTTCAATTTAGCGAGCGCACCCTGGCCAACGGGCTTCGGGTGCTGTTGGTGGAAGATCAC
ACCTCGCCCACGGTGGCCATCCAGGTCGCTTACCGGGTCGGGGGCAAGGACGACCCGCCCGGCCGTTCGGGCTTTGCGCA
TCTGTTTGAGCACCTGATGTTCAAGGGAACGGCCAACACCAAACCGGAGACCCTGGATCGGCTCACCGAGGATGTGGGCG
GCTTCAACAACGCCTTTACCTCCGAGGACATCACCAACTACTTCGAAGTGGTGCCCTCCAACTATCTGGAGACGCTTCTG
TGGGCGGAGGCCGACCGCCTCGGGTCGCTCGTCGTCGATGAGACCAACTTCAAGACCGAGCGGCAGGTGGTGATTGGCGA
GTACGACCAGCGCGTGCTGGCCAGTCCCTACGGCATGCTCTTCGAACTGCTCGACAGCAAGTCCTACACGGTGCACCCTT
ACCGCCGGGGGGTGATCGGCAATCCGGCCGAACTGAACGCCGCCACCCTCGAAGATGTCCAGAATTTCCACCGCACCTAC
TACCAGCCGGACAACACCACGCTGGTGGTGGTGGGGGACTTTGACCCGGTCCAGGCCAACCGGTGGATCGACCAGTACTT
TGGCGCAGTACCCAACAATTCCCGGCCGATTCCGCGGGTGAGCGCCGTCGAGCCCAAGCAGAGCGCCGAGCGGCGCACGA
CCCACTACGGCGCCAATGTGCCGCTGCCCGCGGTGGCCCTGGTCTACCACGCCCCGGCGCGCTCCAGTCCCGACCGGGCC
GCCCTCGATGTGCTGGAGAATGTGCTTTCGCAAGGGCAGAGCGCCCGGCTCTACCGCACCCTGGTCTACGAAAAGCAGGT
GGCCTCCCAGGTGTCCGCGAGCGCAGATCTGCGCGAGCAGCCGGGGCTGTTTGTGGTCTACGCCATCTTGAACGCGGGCG
AAAAGCCCGAGCAGGCCCGCACCCTGCTCGACGGCGAAATCGGCAAGCTGCAGCAAGTGCCGGTACCGGAAGCGGAACTG
GCCAAGGCCAAGACCCAACTGATTGCTGAACTGGTGCGCGGCCGGGAGCAGGCCAACAGCCGCGCCACCGAACTGGTGCT
TGCGACCCTGGTAGGCGGAGATCCCAGGCAGGTCAACACCGCCCTCGAAGAGATCGAGAAAGTGACCGCCCAGGACGTGC
AGCGCGTCGCCCGCCAGTATCTGGTGCCCACCAACCGCACCGTCATCGACTACCTGCCCCGGGCGATGCAACCGGCCGGA
CCCACCAAAAAGGAGCGCAAGTCGCCATGA

Upstream 100 bases:

>100_bases
CGGCAACGCCTGCTGGAAGTAATAGAGCGCTTCGGTGTACTGCTGCAACTGAAAGGCACTCAGACCCTGTTCAAGAAGCG
ACATCGCCCAAATCCCATGT

Downstream 100 bases:

>100_bases
AAACGTTGTGTTGGGCGCTGACGGCGATGCTCCTGGCCCCGGGAACGGCGGCTACCGCCCAGACGCAGACCCCGCCTCCT
CCGGGGCCGCCCCCTTCGGT

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MRNSSRCTRGTLDTAPRRWDNVLDLTELFVGRFLLGLMLAGTLSLGAAVRAESEAVPLPPVQFSERTLANGLRVLLVEDH
TSPTVAIQVAYRVGGKDDPPGRSGFAHLFEHLMFKGTANTKPETLDRLTEDVGGFNNAFTSEDITNYFEVVPSNYLETLL
WAEADRLGSLVVDETNFKTERQVVIGEYDQRVLASPYGMLFELLDSKSYTVHPYRRGVIGNPAELNAATLEDVQNFHRTY
YQPDNTTLVVVGDFDPVQANRWIDQYFGAVPNNSRPIPRVSAVEPKQSAERRTTHYGANVPLPAVALVYHAPARSSPDRA
ALDVLENVLSQGQSARLYRTLVYEKQVASQVSASADLREQPGLFVVYAILNAGEKPEQARTLLDGEIGKLQQVPVPEAEL
AKAKTQLIAELVRGREQANSRATELVLATLVGGDPRQVNTALEEIEKVTAQDVQRVARQYLVPTNRTVIDYLPRAMQPAG
PTKKERKSP

Sequences:

>Translated_489_residues
MRNSSRCTRGTLDTAPRRWDNVLDLTELFVGRFLLGLMLAGTLSLGAAVRAESEAVPLPPVQFSERTLANGLRVLLVEDH
TSPTVAIQVAYRVGGKDDPPGRSGFAHLFEHLMFKGTANTKPETLDRLTEDVGGFNNAFTSEDITNYFEVVPSNYLETLL
WAEADRLGSLVVDETNFKTERQVVIGEYDQRVLASPYGMLFELLDSKSYTVHPYRRGVIGNPAELNAATLEDVQNFHRTY
YQPDNTTLVVVGDFDPVQANRWIDQYFGAVPNNSRPIPRVSAVEPKQSAERRTTHYGANVPLPAVALVYHAPARSSPDRA
ALDVLENVLSQGQSARLYRTLVYEKQVASQVSASADLREQPGLFVVYAILNAGEKPEQARTLLDGEIGKLQQVPVPEAEL
AKAKTQLIAELVRGREQANSRATELVLATLVGGDPRQVNTALEEIEKVTAQDVQRVARQYLVPTNRTVIDYLPRAMQPAG
PTKKERKSP
>Mature_489_residues
MRNSSRCTRGTLDTAPRRWDNVLDLTELFVGRFLLGLMLAGTLSLGAAVRAESEAVPLPPVQFSERTLANGLRVLLVEDH
TSPTVAIQVAYRVGGKDDPPGRSGFAHLFEHLMFKGTANTKPETLDRLTEDVGGFNNAFTSEDITNYFEVVPSNYLETLL
WAEADRLGSLVVDETNFKTERQVVIGEYDQRVLASPYGMLFELLDSKSYTVHPYRRGVIGNPAELNAATLEDVQNFHRTY
YQPDNTTLVVVGDFDPVQANRWIDQYFGAVPNNSRPIPRVSAVEPKQSAERRTTHYGANVPLPAVALVYHAPARSSPDRA
ALDVLENVLSQGQSARLYRTLVYEKQVASQVSASADLREQPGLFVVYAILNAGEKPEQARTLLDGEIGKLQQVPVPEAEL
AKAKTQLIAELVRGREQANSRATELVLATLVGGDPRQVNTALEEIEKVTAQDVQRVARQYLVPTNRTVIDYLPRAMQPAG
PTKKERKSP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI155969707, Length=219, Percent_Identity=27.3972602739726, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI46593007, Length=274, Percent_Identity=24.4525547445255, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17553678, Length=441, Percent_Identity=23.5827664399093, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533970, Length=245, Percent_Identity=31.4285714285714, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25146563, Length=219, Percent_Identity=30.1369863013699, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994338, Length=219, Percent_Identity=30.1369863013699, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=219, Percent_Identity=30.1369863013699, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=219, Percent_Identity=30.1369863013699, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=206, Percent_Identity=24.7572815533981, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=403, Percent_Identity=23.3250620347395, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323421, Length=223, Percent_Identity=26.457399103139, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357875, Length=195, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646943, Length=195, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 54063; Mature: 54063

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00467 RIBOSOMAL_L2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNSSRCTRGTLDTAPRRWDNVLDLTELFVGRFLLGLMLAGTLSLGAAVRAESEAVPLPP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VQFSERTLANGLRVLLVEDHTSPTVAIQVAYRVGGKDDPPGRSGFAHLFEHLMFKGTANT
CCCCHHHHHCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KPETLDRLTEDVGGFNNAFTSEDITNYFEVVPSNYLETLLWAEADRLGSLVVDETNFKTE
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCC
RQVVIGEYDQRVLASPYGMLFELLDSKSYTVHPYRRGVIGNPAELNAATLEDVQNFHRTY
CEEEECCHHHHHHHCHHHHHHHHHCCCCCEECHHHCCCCCCCHHCCHHHHHHHHHHHHHH
YQPDNTTLVVVGDFDPVQANRWIDQYFGAVPNNSRPIPRVSAVEPKQSAERRTTHYGANV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PLPAVALVYHAPARSSPDRAALDVLENVLSQGQSARLYRTLVYEKQVASQVSASADLREQ
CHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHC
PGLFVVYAILNAGEKPEQARTLLDGEIGKLQQVPVPEAELAKAKTQLIAELVRGREQANS
CCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RATELVLATLVGGDPRQVNTALEEIEKVTAQDVQRVARQYLVPTNRTVIDYLPRAMQPAG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
PTKKERKSP
CCCCCCCCC
>Mature Secondary Structure
MRNSSRCTRGTLDTAPRRWDNVLDLTELFVGRFLLGLMLAGTLSLGAAVRAESEAVPLPP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VQFSERTLANGLRVLLVEDHTSPTVAIQVAYRVGGKDDPPGRSGFAHLFEHLMFKGTANT
CCCCHHHHHCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KPETLDRLTEDVGGFNNAFTSEDITNYFEVVPSNYLETLLWAEADRLGSLVVDETNFKTE
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCC
RQVVIGEYDQRVLASPYGMLFELLDSKSYTVHPYRRGVIGNPAELNAATLEDVQNFHRTY
CEEEECCHHHHHHHCHHHHHHHHHCCCCCEECHHHCCCCCCCHHCCHHHHHHHHHHHHHH
YQPDNTTLVVVGDFDPVQANRWIDQYFGAVPNNSRPIPRVSAVEPKQSAERRTTHYGANV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PLPAVALVYHAPARSSPDRAALDVLENVLSQGQSARLYRTLVYEKQVASQVSASADLREQ
CHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHC
PGLFVVYAILNAGEKPEQARTLLDGEIGKLQQVPVPEAELAKAKTQLIAELVRGREQANS
CCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RATELVLATLVGGDPRQVNTALEEIEKVTAQDVQRVARQYLVPTNRTVIDYLPRAMQPAG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
PTKKERKSP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]