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The map label for this gene is cysQ [H]

Identifier: 37523214

GI number: 37523214

Start: 3842896

End: 3843720

Strand: Reverse

Name: cysQ [H]

Synonym: gll3645

Alternate gene names: 37523214

Gene position: 3843720-3842896 (Counterclockwise)

Preceding gene: 37523216

Following gene: 37523213

Centisome position: 82.5

GC content: 63.39

Gene sequence:

>825_bases
ATGCAAAGCTTGACACTATCTACCCAACTGATTCAGCAGGTCGTCGATCTCGCCAGGCGGGCGGGAGCAGCGATTATGGA
AATTTATAACCAGGCGGATGTCGGTACAGTCTACAAGGAGGACAACTCGCCCCTGACCCAGGCGGACCTGGTGTCCCACC
GGCTGATTGTCGGCGAGCTGACCAAACTGACCCCGGATCTGCCCGTGCTCTCCGAGGAATCCCGCTCGAAGCCCTATGAG
GAGCGCCGGACCTGGTCGCGCTTCTGGCTGGTCGATCCGATCGACGGCACCAAAGAATTTATCAAGCGCAACGGCGAATT
CACCGTCAACATCGCCTTGATCGAGGACGGCGAGCCGGTGGCGGGGGTGGTGCACGCGCCGGCCGTCCAGACGACCTACT
GGTCGGCCCGCGGCCTGGGCGCCTTCAAGCAAACCGCCGCGGCCGCGGCCCAGCCCATCCGGGCGGCCGTACCCGCGAGC
GCCCCGATGCTGGTGGTCGCCAGCCGTTCCCACAGTGGTGCTGAGACCGAGGCATTTCTTGCCAAACTGCGCGAACTGGG
CGATATCGATGTCATCTCCATCGGCAGTTCCCTGAAACTGTGCCTGGTGGCCGAAGGGGCCGCGCACCTCTATCCGCGCT
ACGGCCCGACTATGGAATGGGACACCGCCGCCGCCCACAGCGTCGTGGTCGAGGCCGGCGGCACCGTCACCAACCTCAAA
GGTGAAACGCTCCAGTACAACAAAGCCGACCTGCTCAATCCGTATTTTGCCGTGCTGGGCGATCTGCCCCCTGAACTGAG
AGCCCAGATCGTCGAACGGCTCTGA

Upstream 100 bases:

>100_bases
GCCGGCCAACAGTGGTAGGCTGCGATCGGTGCACGCCTTCGGCGATCCGGGCCGCCTTGCCGTCCTTTGTCCGGACCACT
TCTATGGAGCTTGAGGCTCG

Downstream 100 bases:

>100_bases
GTGTATCTGCAGTCGCTTCAAGCGCGGGGTGCCAGAAGTGCCCCGCGCTACTTTTGGTCCAAATGGACCCAGTCCATGCC
GGGGGCACTCATCGGCACCC

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MQSLTLSTQLIQQVVDLARRAGAAIMEIYNQADVGTVYKEDNSPLTQADLVSHRLIVGELTKLTPDLPVLSEESRSKPYE
ERRTWSRFWLVDPIDGTKEFIKRNGEFTVNIALIEDGEPVAGVVHAPAVQTTYWSARGLGAFKQTAAAAAQPIRAAVPAS
APMLVVASRSHSGAETEAFLAKLRELGDIDVISIGSSLKLCLVAEGAAHLYPRYGPTMEWDTAAAHSVVVEAGGTVTNLK
GETLQYNKADLLNPYFAVLGDLPPELRAQIVERL

Sequences:

>Translated_274_residues
MQSLTLSTQLIQQVVDLARRAGAAIMEIYNQADVGTVYKEDNSPLTQADLVSHRLIVGELTKLTPDLPVLSEESRSKPYE
ERRTWSRFWLVDPIDGTKEFIKRNGEFTVNIALIEDGEPVAGVVHAPAVQTTYWSARGLGAFKQTAAAAAQPIRAAVPAS
APMLVVASRSHSGAETEAFLAKLRELGDIDVISIGSSLKLCLVAEGAAHLYPRYGPTMEWDTAAAHSVVVEAGGTVTNLK
GETLQYNKADLLNPYFAVLGDLPPELRAQIVERL
>Mature_274_residues
MQSLTLSTQLIQQVVDLARRAGAAIMEIYNQADVGTVYKEDNSPLTQADLVSHRLIVGELTKLTPDLPVLSEESRSKPYE
ERRTWSRFWLVDPIDGTKEFIKRNGEFTVNIALIEDGEPVAGVVHAPAVQTTYWSARGLGAFKQTAAAAAQPIRAAVPAS
APMLVVASRSHSGAETEAFLAKLRELGDIDVISIGSSLKLCLVAEGAAHLYPRYGPTMEWDTAAAHSVVVEAGGTVTNLK
GETLQYNKADLLNPYFAVLGDLPPELRAQIVERL

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=240, Percent_Identity=30, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI116812595, Length=285, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031789, Length=242, Percent_Identity=27.6859504132231, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI221625487, Length=242, Percent_Identity=27.6859504132231, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1790659, Length=251, Percent_Identity=50.996015936255, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1788882, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71995905, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537869, Length=295, Percent_Identity=28.4745762711864, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=260, Percent_Identity=25.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651149, Length=301, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24664918, Length=262, Percent_Identity=29.0076335877863, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357957, Length=251, Percent_Identity=27.4900398406374, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24664922, Length=258, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357303, Length=238, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29693; Mature: 29693

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLTLSTQLIQQVVDLARRAGAAIMEIYNQADVGTVYKEDNSPLTQADLVSHRLIVGEL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TKLTPDLPVLSEESRSKPYEERRTWSRFWLVDPIDGTKEFIKRNGEFTVNIALIEDGEPV
HHCCCCCCCCCCHHCCCCHHHHHCHHHEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCC
AGVVHAPAVQTTYWSARGLGAFKQTAAAAAQPIRAAVPASAPMLVVASRSHSGAETEAFL
EEEEECCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCCHHHHHH
AKLRELGDIDVISIGSSLKLCLVAEGAAHLYPRYGPTMEWDTAAAHSVVVEAGGTVTNLK
HHHHHCCCEEEEEECCCEEEEEEECCHHHHCCCCCCCCCCCCHHHHEEEEECCCEEEECC
GETLQYNKADLLNPYFAVLGDLPPELRAQIVERL
CCCEECCCHHHCCHHHHHHCCCCHHHHHHHHHHC
>Mature Secondary Structure
MQSLTLSTQLIQQVVDLARRAGAAIMEIYNQADVGTVYKEDNSPLTQADLVSHRLIVGEL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TKLTPDLPVLSEESRSKPYEERRTWSRFWLVDPIDGTKEFIKRNGEFTVNIALIEDGEPV
HHCCCCCCCCCCHHCCCCHHHHHCHHHEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCC
AGVVHAPAVQTTYWSARGLGAFKQTAAAAAQPIRAAVPASAPMLVVASRSHSGAETEAFL
EEEEECCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCCHHHHHH
AKLRELGDIDVISIGSSLKLCLVAEGAAHLYPRYGPTMEWDTAAAHSVVVEAGGTVTNLK
HHHHHCCCEEEEEECCCEEEEEEECCHHHHCCCCCCCCCCCCHHHHEEEEECCCEEEECC
GETLQYNKADLLNPYFAVLGDLPPELRAQIVERL
CCCEECCCHHHCCHHHHHHCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]