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The map label for this gene is ribC [H]

Identifier: 37523173

GI number: 37523173

Start: 3799711

End: 3800352

Strand: Direct

Name: ribC [H]

Synonym: gvip489

Alternate gene names: 37523173

Gene position: 3799711-3800352 (Clockwise)

Preceding gene: 37523172

Following gene: 37523174

Centisome position: 81.56

GC content: 62.77

Gene sequence:

>642_bases
ATGTTCACCGGCATCGTCGAGGAGACGGGCACTCTGCTGGCTCTGGGCAGTGAAGAAATCGCCGTTCGGGCTGCGAAAGT
GCTCAAAGACGTGGCCCTGGGCGACAGCATTTCCGTGGACGGTATTTGTCTTACCGTCGTGCGCTTCGACCGCGACAGTT
TCACCGCCGGTCTGTCGCAGGAGACGCTCGATCGCACGACGCTGATTGGCCGCATCCCGGGCGACGCGGTCAACCTCGAA
AGTGCGCTGCGCGCCGGGGGCAAGCTGGGCGGCCACATCGTCACCGGCCACATCGACGGCGTCGGCCGCTGTGTGGCGGT
TCATCCCGCCGGCCTTTCCTGGGAGATCGACTTCGAGGCGCCGCCGGCGGTGGCCCGCTACATCGTCGAAAAAGGCAGCA
TCGCCATCGACGGCATCAGCCTGACGGTGGCCGCCTGCAACACTGCTGGCGATTGGTTCCGGGTAGCGATTATCCCCCAC
AGCTTTGCCGAAACAACCTTGGGTGCAATCAAACCCGGTGACCCAGTCAACCTGGAGGCGGATCTCATCGGCAAGTACGT
CGAGAAGCTTCTGGGCGGCAGTAAACGTGACAGCCAGGAAAACCTGACCCCTGCCTTCCTGGCCGAGCACGGTTTTCTAT
AA

Upstream 100 bases:

>100_bases
AGCGCTACTGGGCCTACCGCGACCGCGCCCTGGCTGCAATTGACACCTTCGGCCGCACCCACGGGCTTGGCGCCGCCCCT
GCGCTTGCGAGGGCCAACTG

Downstream 100 bases:

>100_bases
GTGCAAGCCGTTCTTGAATTGATCCGATCGGTGGTCTTGCAGAGGTTTAGACTGAAGGCATCCAGAAAGAACAAGCCTGT
GACTCAGAATATTGAAGCGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MFTGIVEETGTLLALGSEEIAVRAAKVLKDVALGDSISVDGICLTVVRFDRDSFTAGLSQETLDRTTLIGRIPGDAVNLE
SALRAGGKLGGHIVTGHIDGVGRCVAVHPAGLSWEIDFEAPPAVARYIVEKGSIAIDGISLTVAACNTAGDWFRVAIIPH
SFAETTLGAIKPGDPVNLEADLIGKYVEKLLGGSKRDSQENLTPAFLAEHGFL

Sequences:

>Translated_213_residues
MFTGIVEETGTLLALGSEEIAVRAAKVLKDVALGDSISVDGICLTVVRFDRDSFTAGLSQETLDRTTLIGRIPGDAVNLE
SALRAGGKLGGHIVTGHIDGVGRCVAVHPAGLSWEIDFEAPPAVARYIVEKGSIAIDGISLTVAACNTAGDWFRVAIIPH
SFAETTLGAIKPGDPVNLEADLIGKYVEKLLGGSKRDSQENLTPAFLAEHGFL
>Mature_213_residues
MFTGIVEETGTLLALGSEEIAVRAAKVLKDVALGDSISVDGICLTVVRFDRDSFTAGLSQETLDRTTLIGRIPGDAVNLE
SALRAGGKLGGHIVTGHIDGVGRCVAVHPAGLSWEIDFEAPPAVARYIVEKGSIAIDGISLTVAACNTAGDWFRVAIIPH
SFAETTLGAIKPGDPVNLEADLIGKYVEKLLGGSKRDSQENLTPAFLAEHGFL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=187, Percent_Identity=33.6898395721925, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=230, Percent_Identity=38.2608695652174, Blast_Score=138, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22307; Mature: 22307

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEETGTLLALGSEEIAVRAAKVLKDVALGDSISVDGICLTVVRFDRDSFTAGLSQ
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCH
ETLDRTTLIGRIPGDAVNLESALRAGGKLGGHIVTGHIDGVGRCVAVHPAGLSWEIDFEA
HHHHHHEEEEECCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEECCC
PPAVARYIVEKGSIAIDGISLTVAACNTAGDWFRVAIIPHSFAETTLGAIKPGDPVNLEA
CHHHHHHHHHCCCEEEECEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCHH
DLIGKYVEKLLGGSKRDSQENLTPAFLAEHGFL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MFTGIVEETGTLLALGSEEIAVRAAKVLKDVALGDSISVDGICLTVVRFDRDSFTAGLSQ
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCH
ETLDRTTLIGRIPGDAVNLESALRAGGKLGGHIVTGHIDGVGRCVAVHPAGLSWEIDFEA
HHHHHHEEEEECCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEECCC
PPAVARYIVEKGSIAIDGISLTVAACNTAGDWFRVAIIPHSFAETTLGAIKPGDPVNLEA
CHHHHHHHHHCCCEEEECEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCHH
DLIGKYVEKLLGGSKRDSQENLTPAFLAEHGFL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]